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LINGO1 Protein (AA 37-555) (His tag)

LINGO1 Origin: Mouse Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN5714490
  • Target See all LINGO1 Proteins
    LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 37-555
    Origin
    • 4
    • 3
    Mouse
    Source
    • 4
    • 1
    • 1
    • 1
    Yeast
    Purification tag / Conjugate
    This LINGO1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    PPRCECSAQD RAVLCHRKRF VAVPEGIPTE TRLLDLGKNR IKTLNQDEFA SFPHLEELEL NENIVSAVEP GAFNNLFNLR TLGLRSNRLK LIPLGVFTGL SNLTKLDISE NKIVILLDYM FQDLYNLKSL EVGDNDLVYI SHRAFSGLNS LEQLTLEKCN LTSIPTEALS HLHGLIVLRL RHLNINAIRD YSFKRLYRLK VLEISHWPYL DTMTPNCLYG LNLTSLSITH CNLTAVPYLA VRHLVYLRFL NLSYNPIGTI EGSMLHELLR LQEIQLVGGQ LAVVEPYAFR GLNYLRVLNV SGNQLTTLEE SAFHSVGNLE TLILDSNPLA CDCRLLWVFR RRWRLNFNRQ QPTCATPEFV QGKEFKDFPD VLLPNYFTCR RAHIRDRKAQ QVFVDEGHTV QFVCRADGDP PPAILWLSPR KHLVSAKSNG RLTVFPDGTL EVRYAQVQDN GTYLCIAANA GGNDSMPAHL HVRSYSPDWP HQPNKTFAFI SNQPGEGEAN STRATVPFPF DIKTLIIAT
    Purification
    SDS-PAGE
    Purity
    > 90 %
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))
    Alternative Name
    LIGO1 (LINGO1 Products)
    Synonyms
    lern1 Protein, lrrn6a Protein, unq201 Protein, DKFZp459P0736 Protein, LERN1 Protein, LRRN6A Protein, UNQ201 Protein, 4930471K13Rik Protein, AV148400 Protein, LINGO-1 Protein, Lrrn6a Protein, leucine rich repeat and Ig domain containing 1 Protein, LINGO1 Protein, lingo1 Protein, Lingo1 Protein
    Background
    Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination . Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.1 Publication
    Molecular Weight
    60.8 kDa
    UniProt
    Q9D1T0
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