You are viewing an incomplete version of our website. Please click to reload the website as full version.

Ligand of Numb-Protein X 1 Proteins (LNX1)

LNX1 encodes a membrane-bound protein that is involved in signal transduction and protein interactions. Additionally we are shipping LNX1 Antibodies (44) and LNX1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LNX1 16924 O70263
LNX1 84708 Q8TBB1
Rat LNX1 LNX1 360926  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top LNX1 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

LNX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Ligand of Numb-Protein X 1 (LNX1) Interaction Partners

Zebrafish Ligand of Numb-Protein X 1 (LNX1) interaction partners

  1. Bozozok (Boz, also known as Dharma or Nieuwkoid) as a binding partner and substrate of Lnx-l.

Mouse (Murine) Ligand of Numb-Protein X 1 (LNX1) interaction partners

  1. the PDZ domain-containing protein (show USH1C Proteins) ligand-of-numb protein (show NUMBL Proteins)-X (LNX) is found in complex with the coxsackievirus and adenovirus receptor (show CXADR Proteins) (CAR)

  2. LNX1 may play a role in regulating (show ERBB2 Proteins) neuregulin-1/ErbB signaling in perisynaptic Schwann cells.

  3. LNX1 provides an endocytic scaffold for JAM4 (show IGSF5 Proteins) that is implicated in the reorganization of cell junctions.

Human Ligand of Numb-Protein X 1 (LNX1) interaction partners

  1. LNX was closely related to human gliomas and suggested it plays an important role in gliomas by notch (show NOTCH1 Proteins) signaling.

  2. LNX1-mediated ubiquitination and degradation of PBK (show PBK Proteins) inhibited cell proliferation and enhanced sensitivity to doxorubicin-induced apoptosis.

  3. identify and confirm six novel LNX1 binding partners: KCNA4 (show KCNA4 Proteins), PAK6 (show PAK6 Proteins), PLEKHG5 (show PLEKHG5 Proteins), PKC (show PRRT2 Proteins)-alpha1, TYK2 (show TYK2 Proteins) and PBK (show PBK Proteins), and suggest that LNX1 functions as a signalling scaffold.

  4. The authors found a high level of LNX1 and LNX2 mRNAs in endocarditis, the principal manifestation of chronic Q fever, but not in acute Q fever.

  5. LNX1 and LNX2 interact with CD8alpha and promote its ubiquitylation and endocytosis

  6. Down-regulation of LNX could result in cell cycle arrest in G0/G1 phase through inhibition of beta-catenin (show CTNNB1 Proteins), MAPK (show MAPK1 Proteins), NFkappaB (show NFKB1 Proteins), c-Myc (show MYC Proteins)-dependent pathway and activation of p53 (show TP53 Proteins), TGF-beta (show TGFB1 Proteins)-dependent pathway.

  7. LNX and RhoC (show RHOC Proteins) might be part of a larger protein complex that would have important functions in signaling transduction about regulating the transcriptional activities of AP-1 (show FOSB Proteins).

  8. identifed ligand of Numb protein (show NUMBL Proteins) X as an Np9-interacting partner; findings point to the possibility that Np9 affects tumorigenesis through the LNX/Numb (show NUMB Proteins)/Notch (show NOTCH1 Proteins) pathway

  9. The presence of multiple protein binding domains involved in signal transduction and interaction with Numb (show NUMB Proteins) and SKIP suggested an important role for LNX in tumorogenesis.

  10. The interaction of c-Src with LNX1 depends on the C-terminal PDZ ligand of c-Src.

LNX1 Protein Profile

Protein Summary

This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.

Gene names and symbols associated with LNX1

  • ligand of numb-protein X 1 (LNX1)
  • ligand of numb-protein X 1 (lnx1)
  • ligand of numb-protein X 1 (LOC100226096)
  • ligand of numb-protein X 1 (Lnx1)
  • ligand of numb-protein X 1, E3 ubiquitin protein ligase (LNX1)
  • ligand of numb-protein X 1, E3 ubiquitin protein ligase (Lnx1)
  • fj78f06 protein
  • LNX protein
  • LNX1 protein
  • MPDZ protein
  • PDZRN2 protein
  • si:dkey-12h2.1 protein
  • wu:fj78f06 protein
  • zgc:152906 protein

Protein level used designations for LNX1

ligand of numb-protein X 1 , multi-PDZ-domain-containing protein , E3 ubiquitin-protein ligase LNX , E3 ubiquitin-protein ligase LNX-like , e3 ubiquitin-protein ligase LNX-like , ligand of Numb protein X 1 , ligand of Numb-binding protein 1 , numb-binding protein 1 , PDZ domain-containing ring finger protein 2 , multi-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX

GENE ID SPECIES
422752 Gallus gallus
461322 Pan troglodytes
561226 Danio rerio
697862 Macaca mulatta
100226096 Taeniopygia guttata
100385548 Callithrix jacchus
100474545 Ailuropoda melanoleuca
100487348 Xenopus (Silurana) tropicalis
100565507 Anolis carolinensis
100601961 Nomascus leucogenys
540694 Bos taurus
16924 Mus musculus
84708 Homo sapiens
475143 Canis lupus familiaris
360926 Rattus norvegicus
Selected quality suppliers for LNX1 Proteins (LNX1)
Did you look for something else?