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LIN28A Proteins

(Lin-28 Homolog A (C. Elegans) (LIN28A))
Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting an uridylyltransferase, leading to the terminal uridylation of pre- let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation (By similarity).
LIN28A Protein (AA 3-182) (His tag) LIN28A Protein (AA 3-182) (His tag) LIN28A Protein (AA 3-182) (His tag) (ABIN7123766)

LIN28A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

LIN28A Protein (AA 1-209) (GST tag) LIN28A Protein (AA 1-209) (GST tag) LIN28A Protein (AA 1-209) (GST tag) (ABIN1309449)

LIN28A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

LIN28A Protein (AA 2-209) (His tag) LIN28A Protein (AA 2-209) (His tag) LIN28A Protein (AA 2-209) (His tag) (ABIN3093550)

Crystallography grade LIN28A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

LIN28A Proteins by Grade

Find LIN28A Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

LIN28A Proteins by Origin

Find LIN28A Proteins for a variety of species such as anti-Human LIN28A, anti-Mouse LIN28A, anti-Chicken LIN28A. The species listed below are among those available. Click on a link to go to the corresponding products.

LIN28A Proteins by Source

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LIN28A Proteins by Protein Type

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LIN28A Proteins by Application

Find LIN28A Proteins validated for a specific application such as ELISA, WB, SDS, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

LIN28A Proteins by Biological Activity

Find LIN28A Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular LIN28A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123766
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309449
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093550
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136590
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7386284
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN667750
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2724751
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2468762
Quantity 0.005 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2750452
Quantity 5 applications
Datasheet Datasheet
Reactivity Xenopus tropicalis
Source Yeast
Validations
Cat. No. ABIN1630444
Quantity 1 mg
Datasheet Datasheet
Reactivity Xenopus laevis
Source Yeast
Validations
Cat. No. ABIN1636558
Quantity 1 mg
Datasheet Datasheet
Reactivity Zebrafish (Danio rerio)
Source Yeast
Validations
Cat. No. ABIN1677265
Quantity 1 mg
Datasheet Datasheet
Reactivity Chicken
Source Yeast
Validations
Cat. No. ABIN1629080
Quantity 1 mg
Datasheet Datasheet

Aliases for LIN28A Proteins

lin-28 homolog A (LIN28A) Proteins
lin-28 homolog A (C. elegans) (Lin28a) Proteins
lin-28 homolog A S homeolog (lin28a.S) Proteins
lin-28 homolog A (C. elegans) (lin28a) Proteins
lin-28 homolog A (Lin28a) Proteins
lin-28 homolog A (lin28a) Proteins
AL024421 Proteins
CSDD1 Proteins
csdd1 Proteins
ENSMUSG00000070700 Proteins
Gm10299 Proteins
LIN-28 Proteins
Lin-28 Proteins
lin-28 Proteins
lin-28A Proteins
LIN28 Proteins
Lin28 Proteins
lin28 Proteins
RGD1566408 Proteins
sb:cb650 Proteins
Tex17 Proteins
ZCCHC1 Proteins
zcchc1 Proteins
zgc:55584 Proteins
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