LIN28A Protein (Myc-DYKDDDDK Tag)
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- Target See all LIN28A Proteins
- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LIN28A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human LIN28 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product LIN28A Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
- Alternative Name
- Lin28 (LIN28A Products)
- Synonyms
- CSDD1 Protein, LIN-28 Protein, LIN28 Protein, ZCCHC1 Protein, lin-28A Protein, AL024421 Protein, ENSMUSG00000070700 Protein, Gm10299 Protein, Lin-28 Protein, Lin28 Protein, Tex17 Protein, csdd1 Protein, lin-28 Protein, lin28 Protein, zcchc1 Protein, sb:cb650 Protein, zgc:55584 Protein, RGD1566408 Protein, lin-28 homolog A Protein, lin-28 homolog A (C. elegans) Protein, lin-28 homolog A S homeolog Protein, LIN28A Protein, Lin28a Protein, lin28a.S Protein, lin28a Protein
- Background
- This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.
- Molecular Weight
- 22.6 kDa
- NCBI Accession
- NP_078950
- Pathways
- Stem Cell Maintenance
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