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Loricrin Proteins (LOR)

LOR encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Additionally we are shipping Loricrin Antibodies (17) and Loricrin Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse LOR LOR 30956 Q99K67
LOR 4014 P23490
Rat LOR LOR 502541  
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Top Loricrin Proteins at

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Chemical His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Chemical GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days

LOR Proteins by Origin and Source

Origin Expressed in Conjugate

More Proteins for Loricrin (LOR) Interaction Partners

Mouse (Murine) Loricrin (LOR) interaction partners

  1. Oct-6 and Oct-11 contribute to the regulation of loricrin gene transcription via interaction with AP-1 factors and Sp1/Sp3.

  2. In the absence of loricrin, S. aureus nasal colonisation was significantly impaired.

  3. The decreased expression of epidermal growth factor receptor (EGFR (show EGFR Proteins)), E-cadherin (show CDH1 Proteins), occludin (show OCLN Proteins), and SIRT1 (show SIRT1 Proteins) in the skin of Flg(ft (show FLG Proteins)) mice, compared with those in C57BL/6J mice, is reported.

  4. YY1 (show YY1 Proteins) contributes to specific loricrin gene expression in differentiated keratinocytes by suppression of its transcription in undifferentiated keratinocytes.

  5. nectin-1 (show PVRL1 Proteins) plays a key role in the expression of loricrin in the epidermis

  6. Skin biopsies from STAT6 transgenic mice (show IVL Proteins)were deficient in the expression and production of loricrin and involucrin.

  7. These results indicate AASS knockdown decreases the lysine requirement of the cell via a reduction of lysine catabolism through the saccharopine pathway.

  8. Mice receiving the high-protein diet had greater AASS mRNA compared to mice fed the adequate protein diet.

Human Loricrin (LOR) interaction partners

  1. Authors report a multi-generation family with prominent ichthyosis (show LBR Proteins) and palmoplantar involvement due to a novel mutation in loricrin.

  2. Letter: Knockdown of either filaggrin (show FLG Proteins) or loricrin increases the productions of interleukin (IL)-1alpha, IL-8 (show IL8 Proteins), IL-18 (show IL18 Proteins) and granulocyte macrophage colony-stimulating factor (show CSF2 Proteins) in stratified human keratinocytes.

  3. Studies on human keratinocytes recognized that loricrin expression was inversely related to the expression of the cyclin-dependent kinase (show CDK1 Proteins) inhibitor p21 (show CDKN1A Proteins)

  4. two novel heterozygous frameshift mutations in exon 2 - c.646_647insGCAGCAGGTC, p.Gln216Argfs*123 and c.798_799dupT, p.Gly267Trpfs*69 in loricrin keratoderma patients

  5. Results describe a novel frameshift mutation leading to loricrin keratoderma presenting with colloidion membrane

  6. We found no mutations of Loricrin in two Progressive symmetrical erythrokeratoderma families.

  7. We describe a young man who was a collodion baby and had the typical presentation of Loricrin keratoderma. Direct DNA sequencing identified a heterozygous mutation in the loricrin gene with a single G insertion, 730insG, present in (a) the patient

  8. There were no mutations found in the LOR gene and the true pathogenesis of progressive symmetrical erythrokeratodermia remains unknown.

  9. identified mRNA transcripts from three genes CDSN (show CDSN Proteins), LOR and KRT9 (show KRT9 Proteins), showing strong over-expression in skin samples relative to samples from forensic body fluids, making them suitable markers for skin identification

  10. VEGF (show VEGFA Proteins) release and the subsequent activation of VEGF receptor 2 link loricrin gene mutations to rapid cell proliferation in a cellular model of loricrin keratoderma.

Loricrin (LOR) Protein Profile

Protein Summary

This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.

Gene names and symbols associated with Loricrin Proteins (LOR)

  • loricrin (LOR)
  • loricrin (TVAG_146950)
  • loricrin (TVAG_228830)
  • loricrin (TVAG_228920)
  • loricrin (TVAG_238290)
  • loricrin (TVAG_035050)
  • loricrin (TVAG_070680)
  • Loricrin (Bm1_52290)
  • loricrin (LOC100281109)
  • loricrin (LOC100281170)
  • loricrin (LOC100281318)
  • aminoadipate-semialdehyde synthase (Aass)
  • loricrin (Lor)
  • AI036317 protein
  • LKR protein
  • LKR/SDH protein
  • LOR protein
  • LOR/SDH protein
  • Lorsdh protein
  • RGD1559993 protein
  • S77319 protein
  • SDH protein

Protein level used designations for Loricrin Proteins (LOR)

loricrin , Loricrin , alpha-aminoadipic semialdehyde synthase, mitochondrial , lysine oxoglutarate reductase , saccharopine dehydrogenase , RGD1559993

609440 Canis lupus familiaris
714526 Macaca mulatta
5464469 Trichomonas vaginalis G3
5465148 Trichomonas vaginalis G3
5465157 Trichomonas vaginalis G3
5467355 Trichomonas vaginalis G3
5468010 Trichomonas vaginalis G3
5468969 Trichomonas vaginalis G3
6105342 Brugia malayi
100281109 Zea mays
100281170 Zea mays
100281318 Zea mays
30956 Mus musculus
4014 Homo sapiens
505154 Bos taurus
502541 Rattus norvegicus
16939 Mus musculus
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