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Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. Additionally we are shipping LRP10 Antibodies (26) and many more products for this protein.
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In Mayer-Rokitansky-Kuster-Hauser syndrome in monoztgotic twins, LRP10 (show LRP4 Proteins) was identified as one of the candidate genes.
Increased expression of LRP10 (show LRP4 Proteins) in human neuroblastoma (show ARHGEF16 Proteins) SH-SY5Y cells induces the accumulation of mature APP (show APP Proteins) in the Golgi and reduces its presence at the cell surface and its processing into Abeta (show APP Proteins).
LRP10 (show LRP4 Proteins) may interfere with the formation of the beta-catenin (show CTNNB1 Proteins)/TCF (show HNF4A Proteins) complex and/or its binding to target DNA in the nucleus, and that the extracellular domain of LRP10 (show LRP4 Proteins) is critical for inhibition of the canonical Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway.
These results suggest that LRP9 cycles between the trans-Golgi network, endosomes and the plasma membrane through a GGA dependent-trafficking mechanism.
Data show that Calnuc (show NUCB1 Proteins) is involved in LRP9 endosomal sorting to prevent the delivery of LRP9 to lysosomes.
Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver.
, low-density lipoprotein receptor-related protein 10