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LRP10 Protein (Fc Tag)

LRP10 Origin: Human Host: HEK-293 Cells Recombinant > 88 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317281
  • Target See all LRP10 Proteins
    LRP10 (Low Density Lipoprotein Receptor Related Protein 10 (LRP10))
    Protein Type
    Recombinant
    Origin
    • 5
    • 4
    Human
    Source
    • 6
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This LRP10 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human LRP10 Protein (Fc Tag)
    Sequence
    Met 1-Lys 440
    Characteristics
    A DNA sequence encoding the human LRP10 (Q7Z4F1-1) extracellular domain (Met 1-Lys 440) was fused with the Fc region of human IgG1 at the C-terminus.
    Purity
    > 88 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product LRP10 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    LRP10 (Low Density Lipoprotein Receptor Related Protein 10 (LRP10))
    Alternative Name
    LRP10 (LRP10 Products)
    Synonyms
    LRP9 Protein, MST087 Protein, Lrp9 Protein, LDL receptor related protein 10 Protein, low-density lipoprotein receptor-related protein 10 Protein, LRP10 Protein, Lrp10 Protein
    Background

    Background: Various members of the low-density lipoprotein receptor (LDLR) family have been reported to play a role in APP trafficking and processing and are important risk factors in AD.LDLR-related protein 1 (LRP1) shuttles between the trans-Golgi Network (TGN), plasma membrane (PM), and endosomes.LRP1 is a functional APP receptor involved in APP trafficking and processing. LRP1 interacts directly with the ectodomain of APP and colocalizes with APP at the TGN. LRP1 is a novel APP sorting receptor that protects APP from amyloidogenic processing, suggesting that a decrease in LRP1 function may contribute to the pathogenesis of Alzheimer's disease.

    Synonym: LRP9,MST087,MSTP087

    Molecular Weight
    73 kDa
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