LRP10 Protein (Fc Tag)
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- Target See all LRP10 Proteins
- LRP10 (Low Density Lipoprotein Receptor Related Protein 10 (LRP10))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LRP10 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human LRP10 Protein (Fc Tag)
- Sequence
- Met 1-Lys 440
- Characteristics
- A DNA sequence encoding the human LRP10 (Q7Z4F1-1) extracellular domain (Met 1-Lys 440) was fused with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 88 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product LRP10 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- LRP10 (Low Density Lipoprotein Receptor Related Protein 10 (LRP10))
- Alternative Name
- LRP10 (LRP10 Products)
- Synonyms
- LRP9 Protein, MST087 Protein, Lrp9 Protein, LDL receptor related protein 10 Protein, low-density lipoprotein receptor-related protein 10 Protein, LRP10 Protein, Lrp10 Protein
- Background
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Background: Various members of the low-density lipoprotein receptor (LDLR) family have been reported to play a role in APP trafficking and processing and are important risk factors in AD.LDLR-related protein 1 (LRP1) shuttles between the trans-Golgi Network (TGN), plasma membrane (PM), and endosomes.LRP1 is a functional APP receptor involved in APP trafficking and processing. LRP1 interacts directly with the ectodomain of APP and colocalizes with APP at the TGN. LRP1 is a novel APP sorting receptor that protects APP from amyloidogenic processing, suggesting that a decrease in LRP1 function may contribute to the pathogenesis of Alzheimer's disease.
Synonym: LRP9,MST087,MSTP087
- Molecular Weight
- 73 kDa
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