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Lymphocyte Antigen 86 Proteins (LY86)

May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Additionally we are shipping LY86 Antibodies (103) and LY86 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LY86 9450 O95711
LY86 17084 O88188
Rat LY86 LY86 291359  
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Top LY86 Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,299.00
Details
HOST_Human Human Fc Tag   10 μg Log in to see 5 Days
$137.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details

LY86 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,

Top referenced LY86 Proteins

  1. Human LY86 Protein expressed in Human Cells - ABIN2002421 : Miura, Shimazu, Miyake, Akashi, Ogata, Yamashita, Narisawa, Kimoto: RP105 is associated with MD-1 and transmits an activation signal in human B cells. in Blood 1998 (PubMed)
    Show all 4 references for ABIN2002421

  2. Mouse (Murine) LY86 Protein expressed in Human Cells - ABIN2007251 : Nagai, Shimazu, Ogata, Akashi, Sudo, Yamasaki, Hayashi, Iwakura, Kimoto, Miyake: Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide. in Blood 2002 (PubMed)
    Show all 4 references for ABIN2007251

More Proteins for Lymphocyte Antigen 86 (LY86) Interaction Partners

Human Lymphocyte Antigen 86 (LY86) interaction partners

  1. DNA methylation (show HELLS Proteins) of the LY86 gene is associated with obesity, insulin (show INS Proteins) resistance, and inflammation.

  2. MD-1 may be a disease susceptibility gene for adult asthma in a Southern Han population in China.

  3. Both mouse and human RP105 (show CD180 Proteins)/MD-1 exhibit dimerization of the 1:1 RP105 (show CD180 Proteins)/MD-1 complex, demonstrating a novel organization.

  4. In this study, we produced variants of MD-1 and MD-2 (show LY96 Proteins) in Pichia pastoris. Contrary to previous reports, this study suggests that MD-1 can bind to LPS (show IRF6 Proteins).

  5. in the promoter region we identified 3 SNPs, rs1334710, rs4959389 and rs977785 that are associated with mite-sensitive allergy in Taiwanese children; results suggested that MD-1 could be a susceptible gene for mite-sensitive allergy in Taiwanese children

  6. Identified MD-1 SNP (rs7740529) association with asthma in Taiwanese children and adults.

Mouse (Murine) Lymphocyte Antigen 86 (LY86) interaction partners

  1. Data show that both RP105 (show GPR83 Proteins)/MD-1 and TLR4 (show TLR4 Proteins)/MD-2 (show LY96 Proteins) are expressed in marginal zone (MZ) B cells.

  2. The RP105 (show GPR83 Proteins)/MD-1 complex is a major mediator of adipose tissue inflammation independent of TLR4 (show TLR4 Proteins) signaling and may represent a novel therapeutic target for obesity-associated metabolic disorders.

  3. Heat-inactivated murine serum diminished the ability of sMD-1 to bind RP105 (show GPR83 Proteins).

  4. Both mouse and human RP105 (show GPR83 Proteins)/MD-1 exhibit dimerization of the 1:1 RP105 (show GPR83 Proteins)/MD-1 complex, demonstrating a novel organization.

  5. Together with the binding assay with tetra-acylated lipid IVa, MD-1 is shown to be a lipid-binding coreceptor.

  6. Required for cell surface expression of RP105/CD180 (show CD180 Proteins) and B-cell responsiveness to lipopolysaccharide . RP105 (show GPR83 Proteins)/MD-1 has structural similarity to Toll-like receptor 4 (show TLR4 Proteins)(TRL4)

  7. Regulation of MD-1 expression may control both pregnancy and allograft survival

  8. direct LPS (show TLR4 Proteins) interaction with cell surface TLR4 (show TLR4 Proteins)-MD-2 (show LY96 Proteins) that is distinct from that with MD-2 (show LY96 Proteins) or CD14 (show CD14 Proteins).

  9. A signal via the RP105 (show GPR83 Proteins)/MD-1 complex drves B cells to differentiate into antibody-secreting cells.

Pig (Porcine) Lymphocyte Antigen 86 (LY86) interaction partners

  1. The role of TLR2, TLR4 (show TLR4 Proteins) and RP105 (show CD180 Proteins)/MD1 in the immunoregulatory effect of acidic exopolysaccharides from Lactobacillus plantarum N14 (show CLPTM1 Proteins), is reported.

LY86 Protein Profile

Protein Summary

May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.

Gene names and symbols associated with Lymphocyte Antigen 86 Proteins (LY86)

  • lymphocyte antigen 86 (LY86)
  • lymphocyte antigen 86 (Ly86)
  • major affective disorder 1 (MAFD1)
  • BPAD protein
  • dJ80N2.1 protein
  • LY86 protein
  • MD-1 protein
  • MD1 protein
  • MGC157074 protein
  • MMD-1 protein

Protein level used designations for Lymphocyte Antigen 86 Proteins (LY86)

lymphocyte antigen 86 , MD-1, RP105-associated , ly-86 , protein MD-1 , MD-1 protein

GENE ID SPECIES
478712 Canis lupus familiaris
613856 Bos taurus
711507 Macaca mulatta
745667 Pan troglodytes
789333 Bos taurus
9450 Homo sapiens
17084 Mus musculus
291359 Rattus norvegicus
396639 Sus scrofa
420872 Gallus gallus
4095 Homo sapiens
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