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Lysophosphatidylcholine Acyltransferase 1 Proteins (LPCAT1)

Lysophosphatidylcholine (LPC) acyltransferase (LPCAT\; EC 2.3.1.23) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis (Nakanishi et al., 2006 [PubMed 16704971]).[supplied by OMIM, May 2008].. Additionally we are shipping LPCAT1 Antibodies (36) and LPCAT1 Kits (32) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LPCAT1 361467 Q1HAQ0
LPCAT1 79888 Q8NF37
LPCAT1 210992 Q3TFD2
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Top LPCAT1 Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 20 μg Log in to see 7 to 8 Days
$319.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,042.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

LPCAT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , ,
,
Mouse (Murine) ,
,

Top referenced LPCAT1 Proteins

  1. Human LPCAT1 Protein expressed in Escherichia coli (E. coli) - ABIN1098791 : Kazachkov, Chen, Wang, Zou: Substrate preferences of a lysophosphatidylcholine acyltransferase highlight its role in phospholipid remodeling. in Lipids 2008 (PubMed)
    Show all 2 references for ABIN1098791

More Proteins for Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) Interaction Partners

Human Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) interaction partners

  1. Overexpression of Lysophosphatidylcholine Acyltransferase 1 and Concomitant Lipid Alterations are associated with Gastric Cancer

  2. No disease causing mutations in the LPCAT1 gene were identified, indicating that LPCAT1 either does not confer a genetic predisposition to retinitis pigmentosa, or incidence of mutations in LPCAT1 is particularly rare in patients with retinitis pigmentosa.

  3. Down-regulation of LPCAT1 resulted in a decreased intercellular platelet-activating factor concentration and PAFR (show PTAFR Proteins) expression.

  4. LPCAT1 is an independent predictor of early tumor recurrence of breast carcinoma and represents a novel prognostic biomarker that reflects underlying biological alterations

  5. LPCAT1, a gene involved in the remodeling of phospholipids, was nominally associated with incident SCA risk.

  6. The prognostic impact of LPCAT1 expression was independent of histological and clinical parameters. It is concluded, that LPCAT1 measurement, either alone or in combination, may be utilized for better clinical decision-making.

  7. effect of LPCAT1 overexpression or knockdown on cell proliferation, migration, and invasion in hepatocellular carcinoma cell lines

  8. LPCAT1 correlates with the progression of prostate cancer.

  9. LPCAT1 and -2 have, in addition to their known function in specialized cells, a ubiquitous role in LD-associated lipid metabolism

  10. full LPCAT1 activity is required to achieve the levels of SatPC essential for the transition to air breathing

Mouse (Murine) Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) interaction partners

  1. LPCAT1 interacts with StarD10 (show STARD10 Proteins) and that amino acids 79-271 of LPCAT1 and the steroidogenic acute regulatory protein-related (show STARD3 Proteins) lipid transfer (START) domain of START domain-containing protein 10 (StarD10 (show STARD10 Proteins)) are sufficient for this interaction.

  2. Almost wild-type LPCAT1 expression in photoreceptors with strong rod rhodopsin and M/S cone opsin staining, and normal visually-guided water maze behavioral performances were observed in treated rd11 mice.

  3. Residue Cys (show DNAJC5 Proteins)-211 of the conserved motif III is not essential for catalysis and not sufficient for sensitivity to treatment by sulfhydryl-modifier agents.

  4. evidence of a protein substrate for Lpcat1 and reveal that histone lipidation may occur through its O-palmitoylation as a novel post-translational modification.

  5. LPS (show TLR4 Proteins) appears to destabilize the LPCAT1 protein by GSK-3beta-mediated phosphorylation within a canonical phosphodegron for beta-TrCP (show BTRC Proteins) docking and site-specific ubiquitination.

  6. Studies add another dimension to an essential role for LPCAT1 in retinal photoreceptor homeostasis.

  7. full LPCAT1 activity is required to achieve the levels of SatPC essential for the transition to air breathing

  8. acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1) is predominantly expressed in the lung, in particular in alveolar type II cells.

  9. Results suggest that lysophosphatidylcholine acyltransferase (LPCAT (show LPCAT3 Proteins)) plays a critical role in regulating surfactant phospholipid biosynthesis.

  10. Aytl2 gene is the phosphatidylcholine (show SGMS2 Proteins) reacylating enzyme in RBCs (show SSU1 Proteins); this represents the identification of a plasma membrane lysophospholipid acyltransferase (show AGPAT1 Proteins) and establishes the function of a LPCAT (show LPCAT3 Proteins) protein

LPCAT1 Protein Profile

Protein Summary

Lysophosphatidylcholine (LPC) acyltransferase (LPCAT\; EC 2.3.1.23) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis (Nakanishi et al., 2006

Gene names and symbols associated with LPCAT1

  • lysophosphatidylcholine acyltransferase 1 (LPCAT1)
  • lysophosphatidylcholine acyltransferase 1 (Lpcat1)
  • lysophosphatidylcholine acyltransferase 1 (lpcat1)
  • 2900035H07Rik protein
  • Aytl2 protein
  • BB137372 protein
  • BC005662 protein
  • C87117 protein
  • LPCAT protein
  • PFAAP3 protein
  • rd11 protein
  • RGD1311599 protein
  • si:dkey-261i16.4 protein
  • zgc:158232 protein

Protein level used designations for LPCAT1

acyltransferase like 2 , lysophosphatidylcholine acyltransferase 1 , 1-acylglycerophosphocholine O-acyltransferase , 1-alkylglycerophosphocholine O-acetyltransferase , LPC acyltransferase 1 , LPCAT-1 , acetyl-CoA:lyso-PAF acetyltransferase , acetyl-CoA:lyso-platelet-activating factor acetyltransferase , acyltransferase-like 2 , lyso-PAF acetyltransferase , lysoPAFAT , lysoPC acyltransferase 1 , acyl-CoA:lysophosphatidylcholine acyltransferase 1 , phosphonoformate immuno-associated protein 3 , regulated by phosphonoformate , aytl2 , mLPCAT1

GENE ID SPECIES
461698 Pan troglodytes
710144 Macaca mulatta
100393606 Callithrix jacchus
100435855 Pongo abelii
361467 Rattus norvegicus
79888 Homo sapiens
555969 Danio rerio
100217397 Sus scrofa
210992 Mus musculus
788450 Bos taurus
488066 Canis lupus familiaris
420974 Gallus gallus
100731890 Cavia porcellus
101111661 Ovis aries
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