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Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Additionally we are shipping Lysyl-tRNA Synthetase Antibodies (59) and Lysyl-tRNA Synthetase Proteins (36) and many more products for this protein.
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Results indicate that KRS can promote cell-cell and cellextracellular matrix adhesion for migration.
finding show that enzymatically active Shiga toxins trigger the dissociation of lysyl-tRNA synthetase (KRS) from the multi-aminoacyl-tRNA synthetase complex in human macrophage-like differentiated THP-1 (show GLI2 ELISA Kits) cells and its subsequent secretion.
KRS at the plasma membrane plays new roles in metastatic migration as a signaling inducer, and causes intracellular signaling for cancer dissemination
tRK1 (show NTRK1 ELISA Kits) forms a complex with human enolases and interacts with tRK1 (show NTRK1 ELISA Kits) and human pre-lysyl-tRNA synthetase (preKARS2)
structural characteristics of the KRS-LR interaction on the cell surface
Lysyl-tRNA synthetase plays essential role in HIV replication, transcriptional regulation, cytokine-like signaling. [review]
The KARS variant is identified in two families affected by DFNB89-associated autosomal-recessive nonsyndromic hearing impairment.
C-terminal domain of HIV-1 capsid protein as surrogate for human lysyl tRNA synthetase
A single conformational change triggered by phosphorylation leads to multiple effects driving an exclusive switch of LysRS function from translation to transcription.
Dual role for motif 1 residues of human lysyl-tRNA synthetase in dimerization and packaging into HIV-1.
mitoKARS is the first described member of a group of mitochondrial proteins whose interaction with mutant SOD1 contributes to mitochondrial dysfunction in ALS
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, lysine--tRNA ligase
, lysyl-tRNA synthetase
, lysine tRNA ligase