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M-Phase Specific PLK1 Interacting Protein Proteins (MPLKIP)

The protein encoded by MPLKIP localizes to the centrosome during mitosis and to the midbody during cytokinesis. Additionally we are shipping M-Phase Specific PLK1 Interacting Protein Antibodies (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MPLKIP 136647 Q8TAP9
MPLKIP 66308 Q9D011
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Top M-Phase Specific PLK1 Interacting Protein Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

MPLKIP Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for M-Phase Specific PLK1 Interacting Protein (MPLKIP) Interaction Partners

Human M-Phase Specific PLK1 Interacting Protein (MPLKIP) interaction partners

  1. A novel mutation in the C7orf11 gene causes nonphotosensitive trichothiodystrophy in a multiplex highly consanguineous kindred

  2. This study extends the allelic and phenotypic spectra of MPLKIP-related trichothiodystrophy, to include a splice variant that causes cardiomyopathy as part of the trichothiodystrophy phenotype.

  3. Given the absence of cutaneous photosensitivity in the patients with C7orf11 mutations, together with the protein's nuclear localization, C7orf11 may be involved in transcription but not DNA repair.

  4. Reported mutations in Trichothiodystrophy do not affect TTDN1 response to ultraviolet (UV) light or the steady state level of the repair/transcription factor IIH (TFIIH (show GTF2H1 Proteins)), which is central to the onset of the photosensitive form of TTD (show ERCC2 Proteins).

  5. TTDN1 is phosphorylated in mitosis, and this is required for its interaction with polo-like kinase 1.

M-Phase Specific PLK1 Interacting Protein (MPLKIP) Protein Profile

Protein Summary

The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.

Gene names and symbols associated with MPLKIP

  • M-phase specific PLK1 interacting protein (MPLKIP)
  • M-phase specific PLK1 intereacting protein (Mplkip)
  • 2810021B07Rik protein
  • ABHS protein
  • C7orf11 protein
  • C330007M08Rik protein
  • ORF20 protein
  • Ttdn1 protein

Protein level used designations for MPLKIP

M-phase-specific PLK1-interacting protein , Russell-Silver syndrome region , TTD non-photosensitive 1 protein , TTD non-photosensitive 1 protein homolog

GENE ID SPECIES
136647 Homo sapiens
66308 Mus musculus
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