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MAX Dimerization Protein 3 Proteins (MXD3)

MXD3 encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. Additionally we are shipping MAX Dimerization Protein 3 Antibodies (49) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MXD3 83463 Q9BW11
MXD3 17121 Q80US8
MXD3 252915 Q62912
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Top MAX Dimerization Protein 3 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,486.00
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,486.00
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,486.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,504.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MXD3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced MAX Dimerization Protein 3 Proteins

  1. Human MXD3 Protein expressed in Escherichia coli (E. coli) - ABIN1098770 : Barisone, Yun, Díaz: From cerebellar proliferation to tumorigenesis: new insights into the role of Mad3. in Cell cycle (Georgetown, Tex.) 2008 (PubMed)
    Show all 2 references for ABIN1098770

More Proteins for MAX Dimerization Protein 3 (MXD3) Interaction Partners

Human MAX Dimerization Protein 3 (MXD3) interaction partners

  1. The results suggest that MXD3 is important for survival of Reh (show CES1 Proteins) preB (show PREB Proteins) ALL cells, possibly as an anti-apoptotic factor.

  2. Acute MXD3 activation results in a transient increase in DAOY cell proliferation while persistent activation of MXD3 results in an overall decrease in cell number, suggesting that the time course of MXD3 expression dictates the cellular outcome.

  3. Increased level and/or duration of MXD3 expression ultimately reduces cell numbers via increased cell death and cell cycle arrest in medulloblastoma cells.

Mouse (Murine) MAX Dimerization Protein 3 (MXD3) interaction partners

  1. Mxd3 regulates preadipocyte proliferation and early adipocyte differentiation via Cebpd (show CEBPD Proteins) downregulation in vitro and in vivo.

  2. Results demonstrate that high expression levels of Mad3 in immature B cells induce Id2 expression, which inhibits transcription of genes essential for B cell differentiation.

  3. identification as a novel target for regulation by E2F1 (show E2F1 Proteins)

  4. These studies support a novel role for Mad3 in cerebellar granule neuron precursors proliferation and possibly tumorigenesis.

  5. Adenosine signaling mediates SUMO-1 (show SUMO1 Proteins) modification of IkappaBalpha (show NFKBIA Proteins) during hypoxia and reoxygenation.

MAX Dimerization Protein 3 (MXD3) Protein Profile

Protein Summary

This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.

Gene names and symbols associated with MXD3

  • MAX dimerization protein 3 (mxd3)
  • MAX dimerization protein 3 (LOC100356869)
  • MAX dimerization protein 3 (MXD3)
  • Max dimerization protein 3 (Mxd3)
  • 4631412E13Rik protein
  • bHLHc13 protein
  • Mad protein
  • MAD3 protein
  • Myx protein
  • zgc:66281 protein

Protein level used designations for MXD3

MAX dimerization protein 3 , Max-associated protein 3 , Max-interacting transcriptional repressor MAD3 , class C basic helix-loop-helix protein 13 , max dimerization protein 3 , max dimerizer 3 , max-associated protein 3 , Mad3 , max-interacting transcriptional repressor MAD3

GENE ID SPECIES
550053 Xenopus (Silurana) tropicalis
100356869 Oryctolagus cuniculus
83463 Homo sapiens
489093 Canis lupus familiaris
533359 Bos taurus
17121 Mus musculus
394031 Danio rerio
779069 Xenopus laevis
427629 Gallus gallus
252915 Rattus norvegicus
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