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MHC Class I Polypeptide-Related Sequence B Proteins (MICB)

MICB encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Additionally we are shipping MICB Antibodies (53) and MICB Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MICB 4277 Q29980
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Top MICB Proteins at antibodies-online.com

Showing 9 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 11 Days
$330.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 12 Days
$157.30
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 5 to 7 Days
$187.00
Details
HOST_Human Cells Human His tag,Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MICB Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , ,

Top referenced MICB Proteins

  1. Human MICB Protein expressed in Human Cells - ABIN2003355 : Bauer, Groh, Wu, Steinle, Phillips, Lanier, Spies: Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 3 references for ABIN2003355

More Proteins for MHC Class I Polypeptide-Related Sequence B (MICB) Interaction Partners

Human MHC Class I Polypeptide-Related Sequence B (MICB) interaction partners

  1. Our results suggest that locally sustained expression of MICA (show MICA Proteins) and MICB in the tumor may contribute to the malignant progression of Gastric cancer(GC) and that expression of these ligands predicts an unfavorable prognosis in GC patients presenting large tumors.

  2. Estrogen upregulates MICA (show MICA Proteins)/B expression in human non-small cell lung cancer through the regulation of ADAM17 (show ADAM17 Proteins).

  3. Aligned with MICB*005:02, MICB*030 has a nonsynonymous adenine substitution at nucleotide position 50 in exon 3, leading to amino acid change from serine to arginine at codon 102 of the mature MICB molecule.

  4. This study suggests that NKG2D (show KLRK1 Proteins) ligands shedding of MICA (show MICA Proteins), MICB and ULBP-2 (show ULBP2 Proteins) is a novel pathway in endometriosis complex pathogenesis that impairs Natural Killer Cells cell function.

  5. six RNA-binding proteins that bind and regulate the expression of MICB.

  6. The sMICB serum levels were significantly increased in hepatitis B patients compared to healthy controls. The sMICB serum levels were decreased in a treated hepatocellular carcinoma (HCC (show FAM126A Proteins)) patient group compared to a not-treated HCC (show FAM126A Proteins) patient group.

  7. MICA (show MICA Proteins)/B expression is inhibited by unfolded protein response and associated with poor prognosis in human hepatocellular carcinoma.

  8. Genotoxic stress induces senescence-associated ADAM10 (show ADAM10 Proteins)-dependent release of NKG2D (show KLRK1 Proteins) MIC ligands (MICA (show MICA Proteins), MICB) in multiple myeloma cells.

  9. Data indicate that MHC class I chain-related protein A (MICA (show MICA Proteins))( *)010, MICA (show MICA Proteins)( *)A5 and MHC class I chain-related protein B (MICB)( *)005:02 were the most frequent alleles.

  10. The elevation of soluble MICB during acute primary Dengue virus infections in infants likely represents an immune evasion strategy and contributes to the severity of the acute illness.

MICB Protein Profile

Protein Summary

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules\; however, it does not associate with beta-2-microglobulin or bind peptides.

Gene names and symbols associated with MICB

  • MHC class I polypeptide-related sequence B (MICB)
  • MHC class I-related protein-like (LOC512825)
  • PERB11.2 protein

Protein level used designations for MICB

MHC class I chain-related protein B , MHC class I mic-B antigen , MHC class I-like molecule PERB11.2-IMX , MIC-B , stress inducible class I homolog

GENE ID SPECIES
4277 Homo sapiens
512825 Bos taurus
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