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MICB encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Additionally we are shipping MICB Antibodies (34) and MICB Kits (12) and many more products for this protein.
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Human MICB Protein expressed in Human Cells - ABIN2003355
Bauer, Groh, Wu, Steinle, Phillips, Lanier, Spies: Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. in Science (New York, N.Y.) 1999
Show all 3 references for ABIN2003355
Estrogen upregulates MICA (show MICA Proteins)/B expression in human non-small cell lung cancer through the regulation of ADAM17 (show ADAM17 Proteins).
Aligned with MICB*005:02, MICB*030 has a nonsynonymous adenine substitution at nucleotide position 50 in exon 3, leading to amino acid change from serine to arginine at codon 102 of the mature MICB molecule.
This study suggests that NKG2D (show KLRK1 Proteins) ligands shedding of MICA (show MICA Proteins), MICB and ULBP-2 (show ULBP2 Proteins) is a novel pathway in endometriosis complex pathogenesis that impairs Natural Killer Cells cell function.
six RNA-binding proteins that bind and regulate the expression of MICB.
The sMICB serum levels were significantly increased in hepatitis B patients compared to healthy controls. The sMICB serum levels were decreased in a treated hepatocellular carcinoma (HCC (show FAM126A Proteins)) patient group compared to a not-treated HCC (show FAM126A Proteins) patient group.
MICA (show MICA Proteins)/B expression is inhibited by unfolded protein response and associated with poor prognosis in human hepatocellular carcinoma.
Genotoxic stress induces senescence-associated ADAM10 (show ADAM10 Proteins)-dependent release of NKG2D (show KLRK1 Proteins) MIC ligands (MICA (show MICA Proteins), MICB) in multiple myeloma cells.
Data indicate that MHC class I chain-related protein A (MICA (show MICA Proteins))( *)010, MICA (show MICA Proteins)( *)A5 and MHC class I chain-related protein B (MICB)( *)005:02 were the most frequent alleles.
The elevation of soluble MICB during acute primary Dengue virus infections in infants likely represents an immune evasion strategy and contributes to the severity of the acute illness.
If differential expression by polymorphic MICA (show MICA Proteins) and MICB promoters is confirmed by functional studies, involvement of these genes in disease susceptibility or adverse transplantation outcomes may require knowledge of both promoter and allelic types to make meaningful conclusions.
This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules\; however, it does not associate with beta-2-microglobulin or bind peptides.
MHC class I chain-related protein B
, MHC class I mic-B antigen
, MHC class I-like molecule PERB11.2-IMX
, stress inducible class I homolog