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MICB Protein (Fc Tag,His tag)

MICB Origin: Human Host: HEK-293 Cells Recombinant > 97 % by SDS-PAGE.
Catalog No. ABIN7534002
  • Target See all MICB Proteins
    MICB (MHC Class I Polypeptide-Related Sequence B (MICB))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 8
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This MICB protein is labelled with Fc Tag,His tag.
    Purpose
    Active Recombinant Human MIC-B Protein
    Sequence
    AEPHSLRYNL MVLSQDGSVQ SGFLAEGHLD GQPFLRYDRQ KRRAKPQGQW AENVLGAKTW DTETEDLTEN GQDLRRTLTH IKDQKGGLHS LQEIRVCEIH EDSSTRGSRH FYYDGELFLS QNLETQESTV PQSSRAQTLA MNVTNFWKED AMKTKTHYRA MQADCLQKLQ RYLKSGVAIR RTVPPMVNVT CSEVSEGNIT VTCRASSFYP RNITLTWRQD GVSLSHNTQQ WGDVLPDGNG TYQTWVATRI RQGEEQRFTC YMEHSGNHGT HPVPSG
    Specificity
    Ala23-Gly298
    Purity
    > 97 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    < 0.1 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product MICB Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target
    MICB (MHC Class I Polypeptide-Related Sequence B (MICB))
    Alternative Name
    MIC-B (MICB Products)
    Synonyms
    PERB11.2 Protein, MHC class I polypeptide-related sequence B Protein, MHC class I-related protein-like Protein, MICB Protein, LOC512825 Protein
    Background

    Description: This protein is a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

    Name: MICB,PERB11.2

    Gene ID
    4277
    UniProt
    Q29980
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