Macrophage Scavenger Receptor 1 Proteins (MSR1)

MSR1 encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of MSR1. Additionally we are shipping Macrophage Scavenger Receptor 1 Antibodies (234) and Macrophage Scavenger Receptor 1 Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MSR1 4481 P21757
MSR1 20288 P30204
MSR1 498638  
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Top Macrophage Scavenger Receptor 1 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human MSR1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 2 to 3 Days
$286.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_HEK-293 Cells Human His tag 50 μg Log in to see 2 to 3 Days
$595.00
Details
HOST_HEK-293 Cells Human His tag   100 μg Log in to see 2 to 3 Days
$515.63
Details
HOST_Human Cells Rat His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details

MSR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , ,
Mouse (Murine) ,
,
Rat (Rattus)
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More Proteins for Macrophage Scavenger Receptor 1 (MSR1) Interaction Partners

Human Macrophage Scavenger Receptor 1 (MSR1) interaction partners

  1. SR-A1 suppresses lung cancer metastasis by downregulating SAA1 (show SAA1 Proteins) production in tumor-associated macrophages (TAM (show CCNA1 Proteins)).

  2. PTX2 (show APCS Proteins) was identified PTX2 (show APCS Proteins) as a novel partner for FX, and both proteins cooperated to prevent their SR-AI-mediated uptake by macrophages.

  3. we found that higher percentages of circulating CD14 (show NDUFA2 Proteins)+CD204+, CD14 (show NDUFA2 Proteins)+CD163 (show CD163 Proteins)+CD204+ M2-like monocytes were significantly associated with TNM (show ODZ1 Proteins) stage, lymph node metastasis, and histological differentiation.

  4. Identifying N-linked glycan moiety and motifs in the cysteine-rich domain critical for N-glycosylation and intracellular trafficking of SR-AI and MARCO (show MARCO Proteins).

  5. The P275A Polymorphism in the Macrophage Scavenger Receptor 1 Gene is not associated with Prostate Cancer Risk.

  6. Cyr61 (show CYR61 Proteins) promotes CD204 expression and the migration of macrophages via MEK (show MAP2K1 Proteins)/ERK (show EPHB2 Proteins) pathway in esophageal squamous cell carcinoma

  7. miR (show MLXIP Proteins)-29a promotes scavenger receptor A expression by targeting QKI (show QKI Proteins) during monocyte-macrophage differentiation.

  8. Heptapeptide XD4 activates the class A scavenger receptor (SR-A) on the glia by increasing the binding of Abeta (show APP Proteins) to SR-A, thereby promoting glial phagocytosis of Abeta (show APP Proteins) oligomer in microglia.

  9. The truncating variant Arg293X in the gene encoding SRA (show SRA1 Proteins)-I/II was associated with reduced lung function and with increased risk of COPD (show ARCN1 Proteins) among men, as well as among alpha1-antitrypsin MZ and superoxide dismutase (show SOD1 Proteins)-3 E1I1 heterozygotes.

  10. monomeric collagen type I via CD204 induces phospho-Akt (show AKT1 Proteins) expression shifting alveolar macrophages to the profibrotic M2 type. Innate immune responses induced by collagen monomers might perpetuate pulmonary fibrosis.

Mouse (Murine) Macrophage Scavenger Receptor 1 (MSR1) interaction partners

  1. Data (including data from studies conducted in cells from knockout mice) suggest that signaling via Lpar1 (show LPAR1 Proteins), Cd14 (show CD14 Proteins), and Scara1 mediates uptake of oxidized LDL by macrophages leading to foam cell formation; lysophosphatidic acid (LPA) induces expression of Cd14 (show CD14 Proteins) and Scara1 in macrophages. (Lpar1 (show LPAR1 Proteins) = LPA receptor 1 (show LPAR1 Proteins); Cd14 (show CD14 Proteins) = monocyte differentiation antigen CD14 (show CD14 Proteins); Scara1 = scavenger receptor class A type I)

  2. Common damage-associated molecular patterns (DAMPs) were internalized through the class A scavenger receptors MSR1 and MARCO (show MARCO Proteins) in vitro. In ischemic murine brain, DAMP (show AMPH Proteins) internalization was largely mediated by MSR1. Combined deficiency for Msr1 and Marco (show MARCO Proteins) in infiltrating myeloid cells caused impaired clearance of DAMPs, more severe inflammation, and exacerbated neuronal injury in a murine model of ischemic stroke.

  3. PTX2 (show PITX2 Proteins) was identified PTX2 (show PITX2 Proteins) as a novel partner for FX, and both proteins cooperated to prevent their SR-AI-mediated uptake by macrophages.

  4. this study shows that Msr1 functions as co-receptor along with TLRs for HMGB1 (show HMGB1 Proteins) in M1-type inflammatory macrophages

  5. Our findings demonstrated that ClC-3 (show CLCN3 Proteins) deficiency inhibits atherosclerotic lesion development, possibly via suppression of JNK (show MAPK8 Proteins)/p38 MAPK (show MAPK14 Proteins) dependent SR-A expression and foam cell formation

  6. FAP (show FAP Proteins)-cleaved collagen is a substrate for SR-A-dependent macrophage adhesion.

  7. Macrophages regulate FX plasma levels in an SR-AI-dependent manner.

  8. The results of this results reveal that SRA has important clinical implications for TLR-targeted immunotherapeutical strategy in intracerebral hemorrhage.

  9. these findings suggest that SR-A-mediated dsRNA internalization is independent of innate antiviral signaling.

  10. Our findings imply that SR-A may be an important target for improving therapeutic strategies for type 1 diabetes.

Macrophage Scavenger Receptor 1 (MSR1) Protein Profile

Protein Summary

This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.

Gene names and symbols associated with MSR1

  • macrophage scavenger receptor 1 (MSR1)
  • macrophage scavenger receptor 1 (Msr1)
  • macrophage scavenger receptor 1 isoform type 1-like (LOC100349984)
  • CD204 protein
  • MRS-A protein
  • MSR protein
  • MSR-A protein
  • MSR1 protein
  • phSR1 protein
  • phSR2 protein
  • RGD1564316 protein
  • Scara1 protein
  • Scvr protein
  • SR-A protein
  • SR-AI protein
  • SR-AII protein
  • SRA protein

Protein level used designations for MSR1

macrophage scavenger receptor 1 , macrophage scavenger receptor types I and II-like , macrophage acetylated LDL receptor I and II , macrophage scavenger receptor type III , macrophage scavenger receptor types I and II , scavenger receptor class A member 1 , scavenger receptor class A, member 1 , SR-A , scavenger receptor type A , macrophage scavenger receptor type I

GENE ID SPECIES
464003 Pan troglodytes
709365 Macaca mulatta
100386222 Callithrix jacchus
100602129 Nomascus leucogenys
4481 Homo sapiens
20288 Mus musculus
498638 Rattus norvegicus
281311 Bos taurus
100009067 Oryctolagus cuniculus
482891 Canis lupus familiaris
100511665 Sus scrofa
100731555 Cavia porcellus
100349984 Oryctolagus cuniculus
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