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Major Vault Protein Proteins (MVP)

MVP encodes the major component of the vault complex. Additionally we are shipping Major Vault Protein Antibodies (184) and Major Vault Protein Kits (33) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MVP 9961 Q14764
MVP 78388  
Rat MVP MVP 64681 Q62667
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Top Major Vault Protein Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MVP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Top referenced Major Vault Protein Proteins

  1. Human MVP Protein expressed in Wheat germ - ABIN1311678 : Dortet, Mostowy, Samba-Louaka, Louaka, Gouin, Nahori, Wiemer, Dussurget, Cossart: Recruitment of the major vault protein by InlK: a Listeria monocytogenes strategy to avoid autophagy. in PLoS pathogens 2011 (PubMed)

More Proteins for Major Vault Protein (MVP) Interaction Partners

Purple Sea Urchin (Strongylocentrotus purpuratus) Major Vault Protein (MVP) interaction partners

  1. structure and cellular localization during embryonic development; findings indicate a dramatic relocalization of MVP from the cytoplasm to the nucleus during sea (show Slc25a1 Proteins) urchin embryogenesis

Human Major Vault Protein (MVP) interaction partners

  1. We believe that for the first time, genetic variants at XRCC6 (show XRCC6 Proteins) and MVP genes are associated with risk of more aggressive disease, and would be taken into account when assessing the malignancy of prostate cancer

  2. MVP genetic polymorphisms and haplotypes may not be associated with drug resistance of partial epilepsy in the Chinese Han population.

  3. NSCLCs [ non-small cell lung cancer ] expressing P-gp (show ABCB4 Proteins) [P-glycoprotein ]/LRP (show RPSA Proteins) [ lung resistance-related protein] bear the EGFR (show EGFR Proteins) [epidermal growth factor receptor (show EGFR Proteins)] mutation in exon 19 or 21 easily.

  4. The association of MVP amplification and PTEN deletion could be a potential biomarker in glioblastoma.

  5. Bag3 (show BAG3 Proteins)-MVP is an important complex that regulates a potent prosurvival signaling pathway and contributes to chemotherapy resistance in breast cancer

  6. LDL increases ABCB1 (show ABCB1 Proteins), ABCC1 (show ABCC1 Proteins), and LRP (show RPSA Proteins) expression in a human doxorubicin-resistant uterine sarcoma cell line.

  7. Study demonstrates that vaults have a tumour-promoting potential by stabilizing EGFR (show EGFR Proteins)/PI3K (show PIK3CA Proteins)-mediated migration and survival pathways in human glioblastoma.

  8. USF1 (show USF1 Proteins) binding to an E-box element may be critical for basal MVP promoter activation.

  9. hyperosmotic stress upregulates Sp1 (show PSG1 Proteins) expression levels by inhibiting ubiquitination through the activation of JNK (show MAPK8 Proteins), and the induction of Sp1 (show PSG1 Proteins) expression directly enhances MVP transcription.

  10. the protein levels of MVP, TEP1 and vPARP are actually increased in the highergrade tumors suggesting existence of post-transcriptional regulation of vault component production.

Mouse (Murine) Major Vault Protein (MVP) interaction partners

  1. MVP may fine-tune SR-A (show MSR1 Proteins) activity in macrophages which contributes to the development of atherosclerosis

  2. MVP is hijacked by L. monocytogenes in order to counteract the autophagy process, a finding that could have major implications in deciphering the cellular role of vault particles.

  3. These results suggest that up-regulation of MVP in multi-drug resistance (MDR) may involve chromatin remodeling.

  4. Results suggest that major vault protein functions as a novel scaffold protein (show HOMER1 Proteins) for both SHP-2 (show PTPN11 Proteins) and Erk (show EPHB2 Proteins).

  5. results suggest that MVP makes a substantial contribution to epithelial cell-mediated resistance to infection

  6. The crystal structure of the vault particle solved at 8 A resolution, together with the 2.1-A structure of the seven N-terminal domains (R1-R7) of MVP, provide an explanation for a reversible dissociation induced by low pH.

Zebrafish Major Vault Protein (MVP) interaction partners

  1. MVP is beneficial for functional recovery and axonal regrowth after spinal cord injury in adult zebrafish.

Major Vault Protein (MVP) Protein Profile

Protein Summary

This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.

Gene names and symbols associated with Major Vault Protein Proteins (MVP)

  • major vault protein (mvp)
  • major vault protein (Tc00.1047053510353.10)
  • major vault protein (Tb927.5.4460)
  • major vault protein (Tb10.70.0520)
  • major vault protein (Tb10.70.5840)
  • major vault protein (LmjF05.0060)
  • major vault protein (mvpA)
  • major vault protein (mvpB)
  • major vault protein (MVP)
  • major vault protein (Mvp)
  • protein tyrosine phosphatase, receptor type, A (Ptpra)
  • 2310009M24Rik protein
  • cb771 protein
  • DDBDRAFT_0189284 protein
  • DDBDRAFT_0190582 protein
  • DDBDRAFT_0191259 protein
  • DDBDRAFT_0191337 protein
  • DDB_0189284 protein
  • DDB_0190582 protein
  • DDB_0191259 protein
  • DDB_0191337 protein
  • LRP protein
  • MGC145641 protein
  • mvp protein
  • Tb05.45E22.810 protein
  • VAULT1 protein
  • wu:fb52b05 protein
  • wu:fc02g01 protein

Protein level used designations for Major Vault Protein Proteins (MVP)

major vault protein , major vault protein-alpha , major vault protein B , lung resistance-related protein , lung resistance-associated protein , R-PTP-alpha , protein tyrosine phosphatase alpha , protein-tyrosine phosphatase alpha , receptor-type tyrosine-protein phosphatase alpha

GENE ID SPECIES
575735 Strongylocentrotus purpuratus
779746 Xenopus (Silurana) tropicalis
3535684 Trypanosoma cruzi strain CL Brener
3657553 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3662971 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3663013 Trypanosoma brucei brucei strain 927/4 GUTat10.1
5648865 Leishmania major strain Friedlin
8617265 Dictyostelium discoideum AX4
8628016 Dictyostelium discoideum AX4
100380384 Salmo salar
9961 Homo sapiens
78388 Mus musculus
64681 Rattus norvegicus
373081 Danio rerio
379630 Xenopus laevis
516456 Bos taurus
479783 Canis lupus familiaris
100340748 Oryctolagus cuniculus
100726794 Cavia porcellus
100622738 Sus scrofa
420049 Gallus gallus
101119435 Ovis aries
100172829 Pongo abelii
25167 Rattus norvegicus
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