anti-Mastermind-Like 2 (Drosophila) (MAML2) Antibodies

Acts as a transcriptional coactivator for NOTCH proteins. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MAML2 270118  
MAML2 689844  
MAML2 84441 Q8IZL2
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Top anti-MAML2 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit  Target Name: Maml2  Sample Tissue: Mouse Stomach lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Guinea Pig Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, IP, WB Western Blot and Immunoprecipitation: MAML2 Antibody [ABIN151565] - Detection of Human and Mouse MAML2 by Western Blot (h and m) and Immunoprecipitation (m). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-MAML2 antibody (Cat. No. ABIN151565) used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B), and used for IP at 3 mcg/mg lysate. MAML2 was also immunoprecipitated by another rabbit anti-MAML2 antibodies and (Cat. No. ABIN151564).  Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B). 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Human Mouse Un-conjugated WB MAML2 monoclonal antibody (M03), clone 4A1 Western Blot analysis of MAML2 expression in MCF-7. Detection limit for recombinant GST tagged MAML2 is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

MAML2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MAML2 Antibodies

  1. Human Polyclonal MAML2 Primary Antibody for IHC, IP - ABIN151565 : Oyama, Harigaya, Sasaki, Okamura, Kokubo, Saga, Hozumi, Suganami, Tamura, Nagase, Koga, Nishimura, Sakamoto, Sato, Yoshida, Kitagawa: Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo. in Development (Cambridge, England) 2011 (PubMed)

More Antibodies against MAML2 Interaction Partners

Human Mastermind-Like 2 (Drosophila) (MAML2) interaction partners

  1. MECT1 (show CRTC1 Antibodies)-MAML2 fusion transcript is a driver genetic event in the pathogenesis of primary bronchopulmonary mucoepidermoid carcinoma

  2. A subgroup of MAML2 fusion-negative mucoepidermoid carcinomas are actually clear cell carcinoma of the salivary gland with EWSR1 (show EWSR1 Antibodies) translocation.

  3. This condensed chromatin structure is associated with binding of DNMT3B (show DNMT3B Antibodies) and decreased occupancy of OCT1 (show POU2F1 Antibodies) transcription factor at MAML2 enhancer, suggesting a role of DNMT3B (show DNMT3B Antibodies) in increasing methylation of MAML2 after stilbenoid treatment.

  4. revealing neither correlation between the cellular composition and CRTC1 (show CRTC1 Antibodies)-MAML2 fusions nor presence of CRTC3 (show CRTC3 Antibodies)-MAML2 fusions in cutaneous hidradenoma

  5. MAML2 rearrangement is common and specific for MEC (show CCL28 Antibodies), which makes it a useful diagnostic tool. MAML2 rearrangement also predicts a favorable prognosis.

  6. Detection of the CRTC1 (show CRTC1 Antibodies)/MAML2 fusion transcript provides useful information for MEC (show CCL28 Antibodies) diagnosis but is not associated with differences in survival outcomes.

  7. The molecular basis underlying CRTC1 (show CRTC1 Antibodies)-MAML2 oncogenic functions were identified in mucoepidermoid carcinoma cells.

  8. SNPs in Notch (show NOTCH1 Antibodies) pathway genes may be predictors of cutaneous melanoma disease-specific survival.

  9. We identified MAML2 rearrangements in five of nine odontogenic cysts lined by mucus-secreting cells

  10. Translocation t(11;19)(q14-21;p12-13) in patients with Salivary mucoepidermoid carcinoma was reported , which results in fusion between exons 1 and 2 of MAML2 on chromosome 11q21.Fusion positive, MAML2 re-arrangements are present in 50-70 % of MECs.

MAML2 Antigen Profile

Protein Summary

Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3 (By similarity).

Gene names and symbols associated with MAML2

  • mastermind like 2 (Drosophila) (Maml2) antibody
  • mastermind-like 2 (Drosophila) (MAML2) antibody
  • 5930431H10 antibody
  • BC032967 antibody
  • MAM-3 antibody
  • MAM2 antibody
  • MAM3 antibody
  • MLL-MAML2 antibody

Protein level used designations for MAML2

mastermind like 2 , mastermind-like 2 , mastermind-like protein 2 , mam-2

GENE ID SPECIES
270118 Mus musculus
689844 Rattus norvegicus
84441 Homo sapiens
521194 Bos taurus
485116 Canis lupus familiaris
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