anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Antibodies

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping MMP1 Kits (129) and MMP1 Proteins (44) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MMP1 4312 P03956
MMP1 17386 P33435
MMP1 300339  
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Top anti-MMP1 Antibodies at antibodies-online.com

Showing 10 out of 330 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-MMP1 Antibody Titration: </b>2.5ug/ml<br><b>Positive Control: </b>HT1080 cell lysate <b>Sample Type:</b> Human Macrophange Cells<br><b>Green:</b> primary<br><b>Red:</b> phallodin<br><b>Blue:</b> DAPI<br><b>Yellow:</b> green/red<br><b>Primary Dilution:</b> 1:200<br><b>Secondary Antibody:</b> anti-Rabbit IgG-FITC<br><b>Secondary Dilution: </b>1:1000<br><b>Image Submitted By:</b> Milan Fiala<br>University of California, Los Angeles 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Horse Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-MMP1 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>Jurkat cell lysate <b>Sample Type:</b> Equine Cartilage Explants<br><b>Primary Dilution:</b> 1:800<br><b>Secondary Antibody</b>: Bio-Rad 170-5046 <br><b>Secondary Dilution:</b> 1:100,000<br>Image Submitted By: Adam Williams<br>University of Nottingham 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of MMP1 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MMP1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse PE FACS Detection of MMP-1 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Mouse Anti-Human MMP-1 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$357.65
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat Achilles tendon labeled with Anti-MMP-1 Polyclonal Antibody , Unconjugated, followed by conjugation to the secondary antibody and DAB staining Human colon carcinoma lysate probed with Anti MMP1 Polyclonal Antibody, Unconjugated  at 1:3000 for 90 min at 37˚C. Predicted band 54kD. Observed band size: 27kD and 54kD 100 μL Log in to see 3 to 7 Days
$318.45
Details
Human Rabbit Un-conjugated IF, IHC (p), WB MMP1 Antibody (Center)  western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the MMP1 antibody detected the MMP1 protein (arrow). MMP1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP1 Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-MMP-1 Polyclonal Antibody, Unconjugated (ABIN668931) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat colitis labeled with Anti-MMP-1 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$318.45
Details
Mouse Rabbit Un-conjugated IHC, ELISA, WB The MMP-1 (mouse) Antibody is used in Western blot to detect MMP-1 in mouse liver lysates. MMP-1 staining in mouse lung. Paraffin-embedded mouse lung is stained with MMP-1 Antibody 0.1 mg Log in to see 2 to 6 Days
$327.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HepG2 cells, using MMP-1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details

MMP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MMP1 Antibodies

  1. Human Polyclonal MMP1 Primary Antibody for WB - ABIN3043405 : Man, Gao, Zhang, Liu, Yan, Huang, Liu: Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma. in Cancer biology & therapy 2011 (PubMed)
    Show all 10 Pubmed References

  2. Human Polyclonal MMP1 Primary Antibody for ELISA, IHC - ABIN4334917 : Huu, Matsushita, Jin, Hamaguchi, Hasegawa, Takehara, Fujimoto: FTY720 ameliorates murine sclerodermatous chronic graft-versus-host disease by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin. in Arthritis and rheumatism 2013 (PubMed)
    Show all 4 Pubmed References

  3. Cow (Bovine) Polyclonal MMP1 Primary Antibody for IHC, ELISA - ABIN1582229 : Yang, Lee, Choi, Lee, Kim, Shin, Han, Kang, Chung: Matrix metalloproteinase-1 induces cleavage of exogenous alphaB-crystallin transduced by a cell-penetrating peptide. in Journal of cellular biochemistry 2011 (PubMed)
    Show all 4 Pubmed References

  4. Mouse (Murine) Polyclonal MMP1 Primary Antibody for IF (p), IHC (p) - ABIN668931 : Luo, Zhang, Wang, Hu, Song, Zhang: The inhibitory effect of salmon calcitonin on intervertebral disc degeneration in an ovariectomized rat model. in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2014 (PubMed)
    Show all 3 Pubmed References

  5. Mouse (Murine) Polyclonal MMP1 Primary Antibody for IHC, ELISA - ABIN1586066 : Bonta, Matlung, Vos, Peters, Pannekoek, Bakker, de Vries: Nuclear receptor Nur77 inhibits vascular outward remodelling and reduces macrophage accumulation and matrix metalloproteinase levels. in Cardiovascular research 2010 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal MMP1 Primary Antibody for ICC, FACS - ABIN969287 : Genevay, Finckh, Mezin, Tessitore, Guerne: Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation. in Arthritis research & therapy 2010 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal MMP1 Primary Antibody for FACS, IF - ABIN966588 : Guan, Shu, Fu, Liu, Xu, Wu: Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells. in FEMS microbiology letters 2009 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal MMP1 Primary Antibody for IF (p), IHC (p) - ABIN668466 : Lu, Cao, Liu, Li, Chen, Fu, Zhang, Liu, Luo, Wang, Li, Caterson: The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage. in Cells, tissues, organs 2012 (PubMed)
    Show all 2 Pubmed References

  9. Human Monoclonal MMP1 Primary Antibody for ELISA, ICC - ABIN449883 : Singh, Kindelberger, Nagymanyoki, Ng, Quick, Elias, Yamamoto, Fichorova, Fulop, Berkowitz: Matrix metalloproteinases and their inhibitors and inducer in gestational trophoblastic diseases and normal placenta. in Gynecologic oncology 2011 (PubMed)

  10. Human Polyclonal MMP1 Primary Antibody for ICC - ABIN1883181 : Yamakawa, Uchida, Matthay, Makita: Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells. in American journal of physiology. Lung cellular and molecular physiology 2011 (PubMed)

More Antibodies against MMP1 Interaction Partners

Human Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. Matrix metalloproteinase-1, -8, -9 and the risk of cardiovascular complications in patients with CHD (show CHDH Antibodies) before and after myocardial revascularization.

  2. Results show that the expression level of MMP1 and TIMP1 (show TIMP1 Antibodies) is under the regulation of HAS2 (show HAS2 Antibodies) leading to migration, invasion and EMT (show ITK Antibodies) of oral cancer cells.

  3. DDC (show DDC Antibodies) up-regulated MMP-1 in LX-2 cells through the Akt (show AKT1 Antibodies) and ERK (show EPHB2 Antibodies)/miR (show MLXIP Antibodies)-222/ETS-1 (show ETS1 Antibodies) pathways.

  4. results suggest that MMP1-1607 1G/2G, MMP3 (show MMP3 Antibodies)-1171 5A/6A and MMP9 (show MMP9 Antibodies)-1562 C/T gene polymorphisms have synergistic effect on breast cancer. The interactions of MMPs clinical risk factors such as lymph node involvement has shown a strong correlation and might influence the 5-years survival rate, suggesting their potential role in the breast carcinogenesis

  5. The MMP-1 -1607 (2G/1G) and -519 (A/G) polymorphisms may contribute to the onset of osteomyelitis. The 2G/2G genotype carriers had 1.605 times risk of developing osteomyelitis. In addition, frequency of -519GG genotype was obviously higher in case group than that in control group, and GG genotype related to an increased risk of osteomyelitis. Whereas, the -519G allele may be a susceptible factor for osteomyelitis.

  6. No differences in the distribution of the MMP-1 variants were found among Tunisian chronic obstructive pulmonary disease patients and healthy controls. Additionally, no significant association was retrieved between clinicopathologic parameters of chronic obstructive pulmonary disease, MMP-1 levels and this polymorphism.

  7. In American cutaneous leishmaniasis caused by Leishmania braziliensis infection, MMP1 is regulated by factors other than FLI1 (show FLI1 Antibodies), and the influence of IL-6 (show IL6 Antibodies) on MMP1 was independent of its effect on FLI1 (show FLI1 Antibodies).

  8. MMP1 was produced in the tumor compartment of prostate cancer bone metastases, highlighting its accessibility to KLK4 (show KLK4 Antibodies) at this site

  9. EREG (show EREG Antibodies) and MMP-1 were found to be elevated in nasal polyp and uncinate tissues in patients with Chronic rhinosinusitis with nasal polyps.

  10. IL-21 (show IL17C Antibodies) levels in rheumatoid arthritis synovial fluid were associated with matrix metalloproteinase (MMP)-1 and MMP-3 (show MMP3 Antibodies).

Pig (Porcine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. the identification of MMP1 and MMP10 (show MMP10 Antibodies) genes in swine is reported.

  2. increased interstitial MMP1 activity during ischemia and reperfusion is a result of the endothelin protein kinase c (show PKC Antibodies) pathway and may be due to enhanced phosphorylation of mmp1

  3. Results indicate that leukemia inhibitory factor (LIF (show LIF Antibodies)) and Oncostatin M (show OSM Antibodies) increase the expression of MMP-1, MMP-3 (show MMP3 Antibodies), and TIMP-1 (show TIMP1 Antibodies) several fold, and that their expression is reduced to basal levels in the presence of the LIF (show LIF Antibodies) antagonist MH35-BD.

Fruit Fly (Drosophila melanogaster) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. Mmp1 negatively regulates ectopic eye differentiation by restricting the rate of proliferation and the levels of expression of retinal-determining genes dachshund and eyes absent.

  2. Data indicate that matrix metalloproteinases mmp1 and mmp2 (show MMP2 Antibodies) mutants have distinct heart phenotypes.

  3. These data demonstrate that Mmp1 modulates PDF processing, which leads to daily structural remodeling and circadian behavior.

  4. A primary function of Mmp1, under the control of the JNK (show MAPK8 Antibodies) pathway, is to promote basement membrane repair, which in turn may permit cell migration and the restoration of a continuous tissue.

  5. Drosophila Mmp1 is involved in the regulation of ISC proliferation for maintenance of gut (show GUSB Antibodies) homeostasis

  6. Study identified three genes, regeneration (rgn (show RGN Antibodies)), augmenter of liver regeneration (alr (show GFER Antibodies)) and Matrix metalloproteinase-1 (Mmp1) expressed specifically in blastema cells during disc regeneration.

Mouse (Murine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. the phenotype seen in the Hdac4 (show HDAC5 Antibodies)(-/-) mice is partially derived from elevation in MMP-13 (show MMP13 Antibodies) and may be due to a bone remodeling disorder caused by overexpression of this enzyme.

  2. MEF2C (show MEF2C Antibodies) is necessary for Mmp13 (show MMP13 Antibodies) gene expression at the transcriptional level and participates in PTH (show PTH Antibodies)-stimulated Mmp13 (show MMP13 Antibodies) gene expression by increased binding to c-FOS at the AP-1 (show JUN Antibodies) site in the Mmp13 (show MMP13 Antibodies) promoter.

  3. data reveal a novel involvement of MMP-13 (show MMP13 Antibodies) in regulating dendritic cell (DC) immunobiology through moderating MHC-I surface presentation, endocytosis and cytokine/chemokine (show CCL1 Antibodies) secretion; furthermore, the reduced MHC-I surface presentation by DCs resulted in a poor CD8 (show CD8A Antibodies)(+) T-cell response in vitro; MMP-13 (show MMP13 Antibodies) might be a promising target for therapeutic intervention in inflammatory diseases

  4. The progressive process of articular cartilage degeneration was significantly delayed in the knee joints of Ddr2 (show DDR2 Antibodies)-deficient mice in comparison to their control littermates. Articular cartilage damage in the knee joints of the mice was associated with increased expression profiles of both Ddr2 (show DDR2 Antibodies) and matrix metalloproteinase 13 (show MMP13 Antibodies).

  5. Postnatal chondrocyte-specific deletion of Hdac3 (show HDAC3 Antibodies) with an inducible Col2a1 (show COL2A1 Antibodies)-Cre caused premature production of pErk1/2 and Mmp13 (show MMP13 Antibodies) in the growth plate.

  6. Mmp13 (show MMP13 Antibodies) is selectively regulated of by 1,25-Dihydroxyvitamin D3, PTH (show PTH Antibodies), and Osterix (show SP7 Antibodies) through distal enhancers.

  7. Our study contributes to the understanding of the role of HIF1alpha (show HIF1A Antibodies) in OA and highlights the HIF1alpha (show HIF1A Antibodies)-beta-catenin (show CTNNB1 Antibodies) interaction, thus providing new insights into the impact of hypoxia in articular cartilage.

  8. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1/protease-activated receptor-1 (show F2R Antibodies) axis may play a role in neurogenesis following physiological and/or pathological stimuli.

  9. IL-1Ra (show IL1RN Antibodies) is associated with MMP-13 (show MMP13 Antibodies) expression and has a novel function in such regulation without interference of the IL-1 (show IL1A Antibodies) signaling cascade.

  10. We reveal a novel role of AP-2epsilon in the regulation of gene expression in articular chondrocytes, as well as in osteoarthritis development, through modulation of Mmp13 (show MMP13 Antibodies) expression and activity.

Cow (Bovine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. BoHV-4 infection affects various pathways related to cell proliferation and cell surface integrity, at least three of which were centered on upregulation of matrix metalloproteinase 1 (MMP1). MMP1 transcription was upregulated by the BoHV-4 transactivator IE2/RTA (show RBM9 Antibodies), leading to abnormally high metalloproteinase tissue levels, potentially leading to defective endometrium healing and unresolved inflammation.

  2. The expression patterns of MMP1, MMP2 (show MMP2 Antibodies), and MMP8 (show MMP8 Antibodies) were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1, MMP2 (show MMP2 Antibodies), and MMP8 (show MMP8 Antibodies) expression levels with meat quality traits were analyzed in cattle. The expression of MMP1, MMP2 (show MMP2 Antibodies), and MMP8 (show MMP8 Antibodies) were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.

  3. Data suggest that luteolytic factors (such as interferon gamma (show IFNG Antibodies), tumor necrosis factor alpha (show TNF Antibodies), and PGF2a) control expression of MMP1, other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.

  4. The results showed that a decrease in MMP-1 and MMP-2 (show MMP2 Antibodies) gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.

  5. Cytoskeletal tension modulates MMP-1 gene expression from tenocytes on micropillar substrates.

  6. MMP-1 promotes VEGFR2 (show KDR Antibodies) expression and proliferation of endothelial cells through stimulation of PAR-1 (show F2R Antibodies) and activation of NF-kappaB (show NFKB1 Antibodies)

  7. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

  8. the differential expression and localization of membrane-type 1 matrix metalloproteinase (show MMP14 Antibodies) in the corpus luteum suggest that it may have multiple functions throughout the course of the estrous cycle,including activation of pro-MMP-2 (show MMP2 Antibodies)

  9. increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 and MMP-13 (show MMP13 Antibodies) (follicular apex (show APEX1 Antibodies) vs. base) for the preovulatory collagenolysis required for follicle rupture

  10. identification of MT1-MMP (show MMP14 Antibodies) in odontoclasts during deciduous tooth resorption might be relevant to the migration activity that these cells have to gain access to the root surface

Rabbit Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. These results suggest that PEP-1-SIRT2 (show SIRT2 Antibodies) promotes matrix metalloproteinases-induced dedifferentiation via ERK (show MAPK1 Antibodies) signaling in articular chondrocytes. .

  2. Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 and decreased TIMP-3 (show TIMP3 Antibodies) secretion.

Horse (Equine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. ANXA2 (show ANXA2 Antibodies) and MMP1 might participate in remodeling during wound healing in the horse.

  2. The polymorphism in the promoter of the MMP-1 gene could be a risk factor for early implant failure of total hip arthroplasty.

  3. These results suggest that MMP-1 and IL-8 (show IL8 Antibodies) are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon.

Xenopus laevis Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

MMP1 Antigen Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MMP1

  • matrix metallopeptidase 1 (MMP1) antibody
  • Matrix metalloproteinase 1 (Mmp1) antibody
  • matrix metalloproteinase 1 (RB11133) antibody
  • matrix metalloproteinase 1 (Mmp1) antibody
  • matrix metallopeptidase 13 (Mmp13) antibody
  • matrix metallopeptidase 1 (interstitial collagenase) (MMP1) antibody
  • matrix metallopeptidase 1 S homeolog (mmp1.S) antibody
  • interstitial collagenase (MMP-1) antibody
  • interstitial collagenase (LOC100727966) antibody
  • matrix metallopeptidase 1 (Mmp1) antibody
  • CG4859 antibody
  • Clg antibody
  • Clgn antibody
  • col4 antibody
  • dm1-MMP antibody
  • Dmel\\CG4859 antibody
  • dmmp1 antibody
  • l(2)k04809 antibody
  • MMP-1 antibody
  • MMP-13 antibody
  • Mmp1 antibody
  • Mmp 1 antibody
  • Mmp1a antibody
  • mmp18 antibody

Protein level used designations for MMP1

fibroblast collagenase , interstitial collagenase , matrix metalloprotease 1 , matrix metalloproteinase 1 , MMP-1 , matrix metalloproteinase 1 (type I collagenase) , matrix metalloproteinase-1 , CG4859-PC , CG4859-PD , CG4859-PE , CG4859-PF , CG4859-PG , CG4859-PH , CG4859-PI , CG4859-PJ , CG4859-PK , CG4859-PL , Mmp1-PC , Mmp1-PD , Mmp1-PE , Mmp1-PF , Mmp1-PG , Mmp1-PH , Mmp1-PI , Mmp1-PJ , Mmp1-PK , Mmp1-PL , Collagenase-3 , collagenase 3 , collagenase-1 , matrix metalloproteinase 13 , matrix metalloproteinase-13 , MMP-18 , collagenase-4 , matrix metalloproteinase-18 , xCol4 , matrix metallopeptidase 1a , matrix metalloproteinase 1a (interstitial collagenase) , myocardial collagenase

GENE ID SPECIES
4312 Homo sapiens
397320 Sus scrofa
37949 Drosophila melanogaster
1790862 Rhodopirellula baltica SH 1
100144547 Bombyx mori
17386 Mus musculus
281308 Bos taurus
100009110 Oryctolagus cuniculus
489428 Canis lupus familiaris
100033896 Equus caballus
495287 Xenopus laevis
443463 Ovis aries
101120355 Ovis aries
100727966 Cavia porcellus
300339 Rattus norvegicus
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