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anti-Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Antibodies

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as art. Additionally we are shipping Matrix Metallopeptidase 13 (Collagenase 3) Kits (113) and Matrix Metallopeptidase 13 (Collagenase 3) Proteins (49) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MMP13 17386 P33435
MMP13 171052  
MMP13 4322 P45452
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Top anti-Matrix Metallopeptidase 13 (Collagenase 3) Antibodies at antibodies-online.com

Showing 10 out of 274 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (p), IP 0.5 mL Log in to see 10 to 12 Days
$554.40
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-MMP13 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Placenta Sample Type: Equine Cartilage Explants  Primary Dilution: 1:1000  Secondary Antibody: Bio-Rad 170-5046 Secondary Dilution: 1:100,000Image Submitted By: Adam WilliamsUniversity of Nottingham 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of MMP13(arrow) using rabbit polyclonal MMP13 Antibody (ABIN390137). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the MMP13 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated IP, IHC, WB Western blot analysis of MMP-13 expression with Jurkat cell lysate. 100 μg Log in to see 2 to 3 Days
$325.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat articular cartilage labeled with Anti-MMP-13 Polyclonal Antibody (ABIN670341), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining Generously provided by Markus Linder from Medical University Vienna as part of the Bioss Discovery Program. Formalin-fixed, paraffin embedded, and decalcified in EDTA mouse bone labeled with Anti-MMP-13 Polyclonal Antibody, Unconjugated (ABIN670341) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Cow Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, SimWes, WB Immunocytochemistry/Immunofluorescence: MMP-13 Antibody [NBP1-45723] - MMP-13 antibody was tested at 1:50 in MDA-MB-231 cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 40x. Western Blot: MMP-13 Antibody [NBP1-45723] - Analysis of MMP-13 in human full-length recombinant protein using anti-MMP-13 antibody. Image from verified customer review. 0.1 mg Log in to see 5 to 7 Days
$389.81
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
$445.50
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details

MMP13 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Matrix Metallopeptidase 13 (Collagenase 3) Antibodies

  1. Human Polyclonal MMP13 Primary Antibody for EIA, IHC (p) - ABIN358686 : Roy-Beaudry, Martel-Pelletier, Pelletier, MBarek, Christgau, Shipkolye, Moldovan: Endothelin 1 promotes osteoarthritic cartilage degradation via matrix metalloprotease 1 and matrix metalloprotease 13 induction. in Arthritis and rheumatism 2003 (PubMed)
    Show all 5 references for ABIN358686

  2. Human Polyclonal MMP13 Primary Antibody for IF (p), IHC (p) - ABIN670341 : Luo, Zhang, Wang, Hu, Song, Su, Zhang: Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats. in Bone 2013 (PubMed)
    Show all 3 references for ABIN670341

  3. Human Monoclonal MMP13 Primary Antibody for IHC (p), IP - ABIN180404 : Pei, Yi: A high-level mammalian expression system based on the Madin-Darby canine kidney cell line. in Protein expression and purification 1998 (PubMed)
    Show all 2 references for ABIN180404

  4. Cow (Bovine) Polyclonal MMP13 Primary Antibody for IP, IHC - ABIN223238 : Spinale, Escobar, Mukherjee, Zavadzkas, Saunders, Jeffords, Leone, Beck, Bouges, Stroud: Cardiac-restricted overexpression of membrane type-1 matrix metalloproteinase in mice: effects on myocardial remodeling with aging. in Circulation. Heart failure 2009 (PubMed)
    Show all 2 references for ABIN223238

  5. Chicken Polyclonal MMP13 Primary Antibody for WB - ABIN2786656 : Borghese, Chiche, Vernerey, Chenot, Mir, Bijaoui, Bonaiti-Pellié, Chapron: Genetic polymorphisms of matrix metalloproteinase 12 and 13 genes are implicated in endometriosis progression. in Human reproduction (Oxford, England) 2008 (PubMed)
    Show all 2 references for ABIN2786656

  6. Cow (Bovine) Polyclonal MMP13 Primary Antibody for ICC, IF - ABIN4334942 : Ma, Liu, Wang, Chen, Liu, Li, Xiang, Wei, Duan, Han: Tamoxifen induces the development of hernia in mice by activating MMP-2 and MMP-13 expression. in Biochimica et biophysica acta 2015 (PubMed)

  7. Human Polyclonal MMP13 Primary Antibody for IHC (p), WB - ABIN390137 : Im, Pacione, Chubinskaya, Van Wijnen, Sun, Loeser: Inhibitory effects of insulin-like growth factor-1 and osteogenic protein-1 on fibronectin fragment- and interleukin-1beta-stimulated matrix metalloproteinase-13 expression in human chondrocytes. in The Journal of biological chemistry 2003 (PubMed)

More Antibodies against Matrix Metallopeptidase 13 (Collagenase 3) Interaction Partners

Zebrafish Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. MeHg impairs tail development at least partially by activation of the tissue remodeling proteases Mmp9 (show MMP9 Antibodies) and Mmp13.

  2. Zebra fish embryogenesis requires MMP-13 and dexamethasone and hydrocortisone modulate the expression of this gene, leading to increased activity and potentially contributing to subsequent dysmorphogenesis.

  3. JNK (show MAPK8 Antibodies)-Mmp13 signaling pathway plays an essential role in regulating the innate immune cell migration in response to severe injury in vivo

Xenopus laevis Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. XCL3 and XCL4 can be differentially induced by prolactin (show PRL Antibodies) and thyroid hormone (show PTH Antibodies)(3)

Mouse (Murine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. Our study contributes to the understanding of the role of HIF1alpha (show HIF1A Antibodies) in OA and highlights the HIF1alpha (show HIF1A Antibodies)-beta-catenin (show CTNNB1 Antibodies) interaction, thus providing new insights into the impact of hypoxia in articular cartilage.

  2. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1 (show MMP1 Antibodies)/protease-activated receptor-1 (show F2R Antibodies) axis may play a role in neurogenesis following physiological and/or pathological stimuli.

  3. IL-1Ra (show IL1RN Antibodies) is associated with MMP-13 expression and has a novel function in such regulation without interference of the IL-1 (show IL1A Antibodies) signaling cascade.

  4. We reveal a novel role of AP-2epsilon in the regulation of gene expression in articular chondrocytes, as well as in osteoarthritis development, through modulation of Mmp13 expression and activity.

  5. B-16 melanoma cells with up-regulated MMP-13 expression promoted invasion of tumor cells through Matrigel compared with control cells transfected with empty vector. Knocked-down MMP-13 expression also decreased invading cell numbers.

  6. MMP-12 (show MMP12 Antibodies) and MMP-13 alter strain K infection in mice and play a role in inflammatory regulation by modulating cytokine levels.

  7. Data indicate that tamoxifen decreased collage type II COL2A1 (show COL2A1 Antibodies) by activating matrix metallopeptidases MMP-2 (show MMP2 Antibodies)/13 expression.

  8. This study demonstrates that stromal as well as tumor derived MMP13 contribute to tumor cell extravasation and establishment of metastases in the liver microenvironment.

  9. Elevated MMP13 activity may contribute to Pseudomonas aeruginosa keratitis through basement membrane degradation.

  10. Mmp13 gene is regulated via at least three specific distal enhancers that display independent activities yet are able to integrate response from multiple signaling pathways in a model of activation and suppression.

Human Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. Findings suggest thatSirt1 may regulate the expression of Runx2 (show RUNX2 Antibodies), which is the osteogenic transcription factor, and the production of MMP-13 from chondrocytes in OA.

  2. the mechanisms and roles of MMP-13 secretion in human small airway epithelial cells and functional polymorphisms of the MMP13 gene

  3. as the grade of late-stage osteoarthritis advanced, levels of TNF-alpha (show TNF Antibodies) in the serum became elevated, whereas levels of MMP-13 in the synovial fluid became elevated

  4. As the grade of late stage osteoarthritis advances, increase in synovial MMP-13 and serum TNF-a (show TNF Antibodies) levels become pronounced.

  5. High MMP13 serum levels are associated with Esophageal Squamous Cell Carcinoma.

  6. Our study demonstrates that miR (show MLXIP Antibodies)-148a inhibits the migration of breast cancer cells by targeting MMP-13

  7. MMP13 expression positively related to the lymph node and distal metastasis, tumor stage and relapse of colorectal cancer

  8. in degenerative intervertebral discs, IL1b (show IL1B Antibodies) upregulates NFkB, MMP13 and ADAMTS4 (show ADAMTS4 Antibodies)

  9. Expression of MMP13 negatively correlated with miR (show MLXIP Antibodies)-27b expression in degenerative nucleus pulposus tissues.

  10. sustained released resveratrol inhibits interleukin-1beta-induced metalloproteinase-13 activation and promotes chondrocyte differentiation

Horse (Equine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. The DNA microarray analysis for matrix metalloproteinase (show MMP20 Antibodies) (MMP)-related mRNA expression in equine superficial digital flexor tendinitis indicated that mRNA level of MMP-13 was apparently up-regulated in the tendinitis as compared to normal tendon.

Cow (Bovine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. p38 (show MAPK14 Antibodies) phosphorylation and MMP13 expression are regulated by Rho/ROCK activation, and support the potential novel pathway that Rho/ROCK is in the upper part of the mechanical stress-induced matrix degeneration cascade in cartilage.

  2. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

  3. MMP-13 treatment of fresh articular cartilage results in cleaved fibromodulin (show FMOD Antibodies) fragments

  4. increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 (show MMP1 Antibodies) and MMP-13 (follicular apex (show APEX1 Antibodies) vs. base) for the preovulatory collagenolysis required for follicle rupture

  5. involvement of p38 MAP kinase (show MAPK14 Antibodies) in the hyaluronan oligosaccharide induction of MMP-13

  6. MMP-13 and collagenase have roles in chondrocyte hypertrophy induced by type II collagen (show COL2A1 Antibodies)

  7. At high but naturally occurring concentrations the collagen peptide CB12 (show PABPC4 Antibodies)-II induced an increase in the expressions of MMP-13 and cleavage of type II collagen (show COL2A1 Antibodies) by collagenase in the mid zone and also in the superficial zone.

Rabbit Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. chitosan-pDNA nanoparticles encoding shRNA targeting MMP-3 (show MMP3 Antibodies) and -13 had great potential in silencing the dedifferentiation-related genes for regenerating prolonged and endurable cartilage.

  2. Leptin (show LEP Antibodies) can induce MMP-13 and have a synergistic induction effect on NO with TNF-alpha (show TNF Antibodies) in rabbit articular chondrocytes in vitro.

Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Antigen Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene names and symbols associated with MMP13

  • matrix metalloproteinase 13a (mmp13a) antibody
  • matrix metalloproteinase 13 (MGC68994) antibody
  • matrix metallopeptidase 13 (collagenase 3) (MMP13) antibody
  • matrix metallopeptidase 13 (collagenase 3) (mmp13) antibody
  • matrix metalloproteinase 13 (LOC100136348) antibody
  • matrix metalloproteinase 13 (mmp13) antibody
  • collagenase 3 (MMP-13) antibody
  • matrix metallopeptidase 13 (Mmp13) antibody
  • matrix metalloproteinase 13 precursor (MMP-13) antibody
  • cb1034 antibody
  • Clg antibody
  • CLG3 antibody
  • gene A antibody
  • MANDP1 antibody
  • MGC108008 antibody
  • MMP-13 antibody
  • Mmp1 antibody
  • MMP13 antibody
  • xcl3 antibody
  • xCol antibody

Protein level used designations for MMP13

matrix metalloproteinase 13 , MMPLg , MMPLh , matrix metallopeptidase 13 (collagenase 3) , collagenase 3 , gene A , gene 11 , collagenase-3 , collagenase 3-like , Collagenase-3 , collagenase-1 , interstitial collagenase , matrix metalloproteinase-13 , MMP-13 , UMRCASE , matrix metalloproteinase 13 (collagenase 3)

GENE ID SPECIES
387293 Danio rerio
379552 Xenopus laevis
451513 Pan troglodytes
493679 Felis catus
613098 Xenopus (Silurana) tropicalis
703980 Macaca mulatta
772008 Gallus gallus
100012553 Monodelphis domestica
100136348 Salmo salar
100396943 Callithrix jacchus
100462632 Pongo abelii
100526826 Ictalurus punctatus
100552256 Anolis carolinensis
100584961 Nomascus leucogenys
397823 Xenopus laevis
17386 Mus musculus
171052 Rattus norvegicus
4322 Homo sapiens
100009711 Equus caballus
281914 Bos taurus
100008685 Oryctolagus cuniculus
398056 Xenopus laevis
395683 Gallus gallus
403763 Canis lupus familiaris
443113 Ovis aries
397346 Sus scrofa
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