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Mediator Complex Subunit 25 Proteins (MED25)

MED25 encodes a component of the transcriptional coactivator complex termed the Mediator complex. Additionally we are shipping Mediator Complex Subunit 25 Antibodies (24) and Mediator Complex Subunit 25 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MED25 81857 Q71SY5
Rat MED25 MED25 292889  
MED25 75613 Q8VCB2
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Top Mediator Complex Subunit 25 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MED25 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Mediator Complex Subunit 25 (MED25) Interaction Partners

Human Mediator Complex Subunit 25 (MED25) interaction partners

  1. the critical region of chromosome 19 a homozygous variant (c.418C>T, p.Arg140Trp) in Mediator complex subunit 25 predicted as deleterious.

  2. A model is proposed in which the N-terminal transactivation domain of ERM (show ETV5 Proteins) binds the MED25 (show MED9 Proteins) VP16 H1 binding pocket in a helical conformation.

  3. Homozygous MED25 (show MED9 Proteins) mutation implicated in eye-intellectual disability syndrome.

  4. MED25 (show MED9 Proteins) is important for regulating the epigenetic landscape resulting in transcriptional activation of a highly inducible gene, CYP2C9 (show CYP2C9 Proteins)

  5. Med25 (show MED9 Proteins) is identified as a new coactivator of ERalpha (show ESR1 Proteins) that is required for ERalpha (show ESR1 Proteins)-mediated regulation of CYP2C9 (show CYP2C9 Proteins) expression

  6. Mediator subunit MED25 (show MED9 Proteins) plays a critical role in this process and identify a MED25 (show MED9 Proteins) domain that serves as a docking site on Mediator for the ATF6alpha (show ATF6 Proteins) transcription activation domain.

  7. the identification of MED25 (show MED9 Proteins) as one of the HNF4alpha (show HNF4A Proteins) binding partners in pancreatic ss-cells leading to insulin (show INS Proteins) secretion which is impaired in MODY (show HNF4A Proteins) patients

  8. solution NMR structure of protein MED25 (show MED9 Proteins)(391-543), comprising the activator interacting domain of subunit 25 of mediator, is presented with the measurement of polypeptide backbone heteronuclear 15N-{1H} NOEs to identify fast internal motional modes

  9. The regulatory interaction between Sox9 (show SOX9 Proteins), Wwp2 (show WWP2 Proteins) and Med25 (show MED9 Proteins) defines the Sox9 (show SOX9 Proteins) transcriptional mechanisms of chondrogenesis in the forming palate.

  10. Preliminary NMR chemical shift mapping showed that VP16 H2 (VP16C) interacts with MED25 (show MED9 Proteins) ACID through one face of the beta-barrel, defined by strands B4-B7-B6.

Mouse (Murine) Mediator Complex Subunit 25 (MED25) interaction partners

  1. the identification of MED25 as one of the HNF4alpha (show HNF4A Proteins) binding partners in pancreatic ss-cells leading to insulin (show INS Proteins) secretion which is impaired in MODY (show HNF4A Proteins) patients

  2. Data show that Med25 is coordinately expressed with Pmp22 (show PMP22 Proteins) gene dosage and expression in transgenic mice and rats, and suggest a potential role of this protein in the molecular etiology of Charcot-Marie-Tooth disease.

Mediator Complex Subunit 25 (MED25) Protein Profile

Protein Summary

This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2.

Gene names and symbols associated with MED25

  • Mediator complex subunit 25 (MED25)
  • mediator complex subunit 25 (MED25)
  • mediator complex subunit 25 (med25)
  • mediator complex subunit 25 (LOC100343629)
  • mediator complex subunit 25 (Med25)
  • mediator of RNA polymerase II transcription, subunit 25 homolog (yeast) (Med25)
  • mediator of RNA polymerase II transcription, subunit 25 homolog (yeast) (med25)
  • 2610034E13Rik protein
  • 2610529E18Rik protein
  • ACID1 protein
  • ARC92 protein
  • CG12254 protein
  • CMT2B2 protein
  • dARC92 protein
  • dDrip97 protein
  • Dmel\\CG12254 protein
  • ESTM2 protein
  • LD07688 protein
  • med25 protein
  • P78 protein
  • PTOV2 protein
  • RGD1305137 protein
  • X83308 protein
  • zgc:63555 protein

Protein level used designations for MED25

mediator complex subunit 25 , CG12254-PA , MED25-PA , mediator of RNA polymerase II transcription, subunit 25 homolog , mediator of RNA polymerase II transcription subunit 25 , mediator of RNA polymerase II transcription subunit 25-like , ARC/mediator transcriptional coactivator subunit , activator interaction domain-containing protein 1 , activator-recruited cofactor 92 kDa component , prostate-derived protein 78 kDa , mMED25 , mediator of RNA polymerase II transcription, subunit 9 homolog

GENE ID SPECIES
42385 Drosophila melanogaster
484374 Canis lupus familiaris
719061 Macaca mulatta
100124831 Xenopus (Silurana) tropicalis
100343629 Oryctolagus cuniculus
100385076 Callithrix jacchus
100444927 Pongo abelii
81857 Homo sapiens
292889 Rattus norvegicus
533865 Bos taurus
444205 Xenopus laevis
75613 Mus musculus
406793 Danio rerio
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