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MTNR1A encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. Additionally we are shipping Melatonin Receptor 1A Antibodies (104) and Melatonin Receptor 1A Kits (5) and many more products for this protein.
Showing 10 out of 12 products:
findings suggest that a variant near MTNR1A may be associated with job-related exhaustion in shift workers
By integrating genetic and epigenetic data, we identified that a differentially methylated CpG site within the melatonin receptor 1A (MTNR1A) gene mediates the effect of a paternally transmitted genetic variant on the comorbidity of asthma and AR. This study provides a novel insight into the role of epigenetic mechanisms in patients with allergic respiratory diseases.
MT1 (show MT1A Proteins) is part of the presynaptic protein network and negatively regulates Cav (show CA5A Proteins) 2.2 activity, providing a first hint for potential synaptic functions of MT1 (show MT1A Proteins).
rs2119882 polymorphism was associated with polycystic ovary syndrome in Han Chinese. A significant difference in transmission of allele C of rs2119882 was found between obese and non-obese women with PCOS.
results support gene-environment interactions of MTNR1A polymorphisms with smoking and betel quid-chewing habits possibly altering oral-cancer susceptibility and metastasis
Sections from paraffin-embedded normal tissue from 42 individuals, representing the different parts of the GI tract (n=39) and pancreas (n=3) were studied with immunohistochemistry using antibodies for melatonin, MT1 (show MT1A Proteins) and MT2 (show MT2 Proteins) receptors and serotonin.
There were no significant differences between the expression of MT1 (show MT1A Proteins) and histological type, staging, grading, presence of residual disease, or overall survival time.
genetic polymorphisms rs2119882 in melatonin receptor 1A (MTNR1A) and rs10830963 in melatonin receptor 1B (MTNR1B) are associated with an increased risk of developing gestational diabetes mellitus and insulin resistance in Han Chinese women
this study provides a detailed delineation of the melatonin-mediated activation of ERK1/2 in HEK293 cells that are transfected with melatonin receptor MT1 (show MT1A Proteins).
Genetic inactivation of both transgenic MT1 (show MT1A Proteins) and MT2 (show MT2 Proteins) receptors produces an increase of wakefulness, likely as a result of reduced NREMS due to the lack of MT2 (show MT2 Proteins) transgene receptors, and reduced REMS induced by the lack of MT1 (show MT1A Proteins) transgene receptors.
The expression of the melatonin receptors MT1 (show MT1 Proteins) and MT2 (show MT2 Proteins) and the regulatory role of melatonin in the development of bovine Sertoli cells are reported.[MT1 (show MT1 Proteins); MT2 (show MT2 Proteins)]
The study revealed that ASMT (show ASMT Proteins) and MTNR1A genes were expressed in cumulus-oocyte complexes (COCs).
This article presents the first evidence showing expression of mt1A (show MT1A Proteins) melatonin receptor in bovine cerebral arteries.
Ecto-5'-nucleotidase (show ACPP Proteins) mRNA levels were found to be diminished in both MT1 (show MT1 Proteins) and MT1 (show MT1 Proteins)/2 knockout mice.
The removal of MT1R or MT2R in mice abolished the daily rhythm in blood glucose levels, but produced small effects on the rhythmic expression patterns of clock genes within skeletal muscle, liver, and adipose tissue.
MT1 (show MT1 Proteins) melatonin receptors are involved in neural pathways modulating diurnal rhythms of spontaneous behavior in the homecage as well as pathways regulating depressive and anxiolytic-like behaviors.
These data demonstrate that melatonin MT1 (show MT1 Proteins) receptor knockout mice recapitulate several behavioral and neurobiological circadian changes.
The effect of miR (show MLXIP Proteins)-29b on endothelial permeability and apoptosis is mediated through the down-regulation of melatonin receptor 1.
there is an an increased proinflammatory status of mice deficient in both membrane-bound melatonin receptors reflected by altered activation of MAPK (show MAPK1 Proteins) cascades and transcriptional activation of proinflammatory mediators
This study demonistrated that METH (show MTRR Proteins)-induced CPP is dependent on time of day and the presence of the MT1 (show MT1 Proteins) receptor, suggesting a role for melatonin in METH (show MTRR Proteins)-induced reward.
Heteromeric MT1/MT2 (show MT1 Proteins) melatonin receptors modulate photoreceptor function.
These data suggest that melatonin, by acting on MT1 receptors, affects NeuroD expression in the gastrointestinal tract and thus might contribute to circadian regulation in metabolic functions.
MT1R signaling and BMP-4 (show BMP4 Proteins) actions are mutually augmented, leading to fine-tuning of ACTH (show POMC Proteins) production by corticotrope cells.
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
melatonin receptor 1A
, melatonin receptor type 1A
, mel1a receptor-like
, melatonin receptor Mel1a Z1.4
, melatonin receptor type 1A z1.4
, melatonin receptor type 1A-like
, mel1a receptor
, Mel1a receptor
, mel1a melatonin receptor
, Mel-1a melatonin receptor
, Mel1a melatonin receptor
, Melatonin receptor type 1A
, G-protein coupled receptor