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anti-Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) Antibodies

The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008].. Additionally we are shipping MGEA5 Proteins (5) and MGEA5 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MGEA5 10724 O60502
MGEA5 76055 Q9EQQ9
MGEA5 154968 Q8VIJ5
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Top anti-MGEA5 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IP Immunoprecipitation of MGEA5 transfected lysate using anti-MGEA5 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with MGEA5 MaxPab mouse polyclonal antibody (B01) . 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated IF, ELISA, WB Detection limit for recombinant GST tagged MGEA5 is 0.3 ng/ml as a capture antibody. Immunofluorescence of monoclonal antibody to MGEA5 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.45 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Biotin ELISA   100 μg Log in to see 8 to 10 Days
$537.17
Details
Mouse Rabbit Biotin ELISA   100 μg Log in to see 8 to 10 Days
$537.17
Details
Rat Rabbit Biotin ELISA   100 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Biotin ELISA, WB   100 μg Log in to see 8 to 10 Days
$610.50
Details
Mouse Rabbit Biotin ELISA, WB   100 μg Log in to see 8 to 10 Days
$610.50
Details
Human Rabbit FITC WB   100 μg Log in to see 8 to 10 Days
$639.83
Details
Rat Rabbit Biotin ELISA, WB   100 μg Log in to see 8 to 10 Days
$639.83
Details

MGEA5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against MGEA5 Interaction Partners

Human Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) interaction partners

  1. E2F1 (show E2F1 Antibodies) negatively regulates both Ogt (show OGT Antibodies) and Mgea5 expression in an Rb1 (show RB1 Antibodies) protein-dependent manner.

  2. OGA overexpression in endothelial cells improves endothelial function and may have a beneficial effect on coronary vascular complications in diabetes.

  3. Amino acid composition of splice variants, post-translational modifications, and stable associations with regulatory proteins influence subcellular distribution/substrate specificity of OGA and OGT (O-linked N-acetylglucosamine transferase (show OGT Antibodies)). [REVIEW]

  4. This work identifies the first target of miR (show MLXIP Antibodies)-539 in the heart and the first miRNA that regulates OGA.

  5. Report the presence of TGFBR3 (show TGFBR3 Antibodies) and/or MGEA5 rearrangements in pleomorphic hyalinizing angiectatic tumors and the spectrum of related neoplasms.

  6. Estrogen replacement therapy and plyometric training influence muscle OGT and OGA gene expression, which may be one of the mechanisms by which HRT and PT prevent aging-related loss of muscle mass.

  7. O-linked beta-N-acetylglucosaminylation (O-GlcNAcylation) in primary and metastatic colorectal cancer clones and effect of N-acetyl-beta-D-glucosaminidase silencing on cell phenotype and transcriptome.

  8. Data show that the interplay between O-GlcNAc (show OGT Antibodies) and phosphorylation on proteins and indicate that these effects can be mediated by changes in hOGT and hOGA (show OAT Antibodies) kinetic activity.

  9. Analysis of urinary content of MGEA5 and OGT (show OGT Antibodies) may be useful for bladder cancer diagnostics.

  10. Decrease in MGEA5 and increase in O-GlcNAc transferease expression in higher grade tumors suggests that increased O-GlcNAc modification may be implicated in breast tumor progression and metastasis.

Mouse (Murine) Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) interaction partners

  1. Oga(+/-) mice resist high-fat diet-induced obesity with ameliorated hepatic steatosis and improved glucose metabolism

  2. plays a critical role in placental vasculogenesis by modulating HIF-1alpha (show HIF1A Antibodies) stabilization

  3. E2F1 (show E2F1 Antibodies) negatively regulates both Ogt (show OGT Antibodies) and Mgea5 expression in an Rb1 (show RB1 Antibodies) protein-dependent manner.

  4. Conditional disruption of the O-GlcNAcase in mice leads to metabolic deregulation and semi-penetrant perinatal lethality.

  5. This work identifies the first target of miR (show MLXIP Antibodies)-539 in the heart and the first miRNA that regulates OGA.

  6. The O-GlcNAcase active site resembles those of glycosidases which carry out the hydrolysis of GlcNAc linkages in a substrate-assisted acid-base manner.

Pig (Porcine) Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) interaction partners

  1. Data suggest that enzymes in hexosamine biosynthesis pathway and downstream protein O-GlcNAcylation are important for preimplantation development; these include Oga, Gfpt (glutamine-fructose-6-P aminotransferase), and Ogt (O-GlcNAc transferase).

MGEA5 Antigen Profile

Protein Summary

The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001

Gene names and symbols associated with MGEA5

  • meningioma expressed antigen 5 (hyaluronidase) (MGEA5) antibody
  • meningioma expressed antigen 5 (hyaluronidase) (Mgea5) antibody
  • 2810009A20Rik antibody
  • 4833427O07Rik antibody
  • 5830447M11Rik antibody
  • AA408215 antibody
  • Hy5 antibody
  • MEA5 antibody
  • mKIAA0679 antibody
  • Ncoat antibody
  • O-GLCNACASE antibody
  • OGA antibody

Protein level used designations for MGEA5

O-GlcNAcase , bifunctional protein NCOAT , hyaluronidase in meningioma , meningioma-expressed antigen 5 , nuclear cytoplasmic O-GlcNAcase and acetyltransferase

GENE ID SPECIES
10724 Homo sapiens
76055 Mus musculus
154968 Rattus norvegicus
477802 Canis lupus familiaris
100152585 Sus scrofa
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