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MGEA5 antibody

MGEA5 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7130225
  • Target See all MGEA5 Antibodies
    MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
    Reactivity
    • 38
    • 23
    • 15
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 55
    • 6
    Rabbit
    Clonality
    • 49
    • 12
    Polyclonal
    Conjugate
    • 30
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MGEA5 antibody is un-conjugated
    Application
    • 45
    • 21
    • 15
    • 12
    • 10
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Antigen affinity purification
    Immunogen
    Fusion protein of Human MGEA5
    Isotype
    IgG
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    Discover our top product MGEA5 Primary Antibody
  • Application Notes
    ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
    Alternative Name
    MGEA5 (MGEA5 Products)
    Synonyms
    MEA5 antibody, NCOAT antibody, OGA antibody, 2810009A20Rik antibody, 4833427O07Rik antibody, 5830447M11Rik antibody, AA408215 antibody, Hy5 antibody, Ncoat antibody, mKIAA0679 antibody, O-GLCNACASE antibody, cytochrome c oxidase subunit VIc antibody, meningioma expressed antigen 5 (hyaluronidase) antibody, COX6C antibody, MGEA5 antibody, Mgea5 antibody
    Background

    Background: The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT, which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications. Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates 'Lys-8' of histone H4 and 'Lys-14' of histone H3. Shows highest expression in the brain, placenta and pancreas.

    Aliases: Beta-hexosaminidase antibody, Beta-N-acetylglucosaminidase antibody, Beta-N-acetylhexosaminidase antibody, Bifunctional protein NCOAT antibody, HEXC antibody, Hyaluronidase in meningioma antibody, KIAA0679 antibody, MEA5 antibody, Meningioma expressed antigen 5 antibody, Meningioma-expressed antigen 5 antibody, MGEA 5 antibody, Mgea5 antibody, N-acetyl-beta-D-glucosaminidase antibody, N-acetyl-beta-glucosaminidase antibody, NCOAT antibody, Nuclear cytoplasmic O GlcNAcase and acetyltransferase antibody, Nuclear cytoplasmic O-GlcNAcase and acetyltransferase antibody, OGA antibody, OGA_HUMAN antibody, Protein O-GlcNAcase antibody

    UniProt
    O60502
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
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