anti-Metal-Regulatory Transcription Factor 1 (MTF1) Antibodies

MTF1 encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. Additionally we are shipping MTF1 Kits (6) and MTF1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MTF1 17764 Q07243
MTF1 4520 Q14872
MTF1 362591  
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Top anti-MTF1 Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-MTF1 Antibody Titration: </b>5.0ug/ml<br><b>ELISA Titer: </b>1:2500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged MTF1 is approximately 0.3ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated ChIP, ICC, IF, IHC, IHC (fro), IHC (p), WB Immunohistochemistry-Paraffin: MTF1 Antibody [NBP1-86380] - Staining of human corpus, uterine shows strong cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: MTF1 Antibody [NBP1-86380] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-MTF-1 Polyclonal Antibody, Unconjugated (ABIN701425) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Cow Rabbit Un-conjugated WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged MTF1 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemistry: MTF1 Antibody (2F3) [NBP2-46027] - Analysis of Carcinoma of Human lung tissue.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min)(1:150) Immunohistochemistry: MTF1 Antibody (2F3) [NBP2-46027] - Analysis of Human Ovary tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min)(1:150) 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

MTF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MTF1 Antibodies

  1. Human Polyclonal MTF1 Primary Antibody for ChIP, ICC - ABIN4335936 : Kim, Jeon, Shin, Won, Lee, Kwak, Lee, Rhee, Ryu, Chun, Chun: Regulation of the catabolic cascade in osteoarthritis by the zinc-ZIP8-MTF1 axis. in Cell 2014 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal MTF1 Primary Antibody for ELISA, WB - ABIN561861 : Zhang, Meyer, Zhang: Fetal exposure to cocaine causes programming of Prkce gene repression in the left ventricle of adult rat offspring. in Biology of reproduction 2009 (PubMed)

More Antibodies against MTF1 Interaction Partners

Zebrafish Metal-Regulatory Transcription Factor 1 (MTF1) interaction partners

  1. The functional characterization of a complete zebrafish MTF-1, is reported.

  2. MTF1 is a master regulator of gene expression during development.

Mouse (Murine) Metal-Regulatory Transcription Factor 1 (MTF1) interaction partners

  1. Findings identify a reciprocal activation mechanism involving HIF-2alpha (show EPAS1 Antibodies) and the zinc-ZIP8 (show SLC39A8 Antibodies)-MTF1 axis during osteoarthritis pathogenesis that amplifies catabolic signaling and cartilage destruction.

  2. MTF1 mediates the increase of CaV3.2 (show CACNA1H Antibodies) mRNA and a rise in intracellular Zn(2+) which is associated with status epilepticus.

  3. the presence of SUMO moiety allows the MTF-1 protein to interact directly with metal-responsive element

  4. nuclear receptor SHP inhibits zinc-dependent induction of Dnmt1 (show DNMT1 Antibodies) by antagonizing metal-responsive transcription factor-1.

  5. MTF-1 DNA-binding activity is strongly enhanced in the presence of zinc.

  6. PTEN (show PTEN Antibodies) associates with MTF-1 in cells in response to oxidative stress and in zinc homeostasis.

  7. Results reveal a novel repressive role for MTF-1 in the regulation of the Zip10 zinc transporter expression by pausing Pol II transcription.

  8. Data show that disruption of nucleosome structure at the MT-I (show MT1 Antibodies) promoter is mediated by zinc-responsive recruitment of an active MTF-1-coactivator complex.

  9. Zinc and cadmium can activate FPN1 (show SLC40A1 Antibodies) transcription through the MTF-1.

  10. mouse MTF-1 is polymorphic

Human Metal-Regulatory Transcription Factor 1 (MTF1) interaction partners

  1. MTF1 (show MFI2 Antibodies) heads a hierarchy of zinc sensors, and through controlling the expression of a raft of metallothioneins and other key proteins involved in controlling intracellular zinc levels (e.g. ZnT1 (show SLC30A1 Antibodies)) alters zinc buffering capacity and total cellular zinc content.

  2. MTF-1 (show MFI2 Antibodies) has a role in regulating zinc dependent cellular processes at the molecular level [review]

  3. Forty-one single nucleotide polymorphisms (SNPs) within the MTF1 (show MFI2 Antibodies) gene region.

  4. Human ZnT2 expression is regulated by MTF-1 (show MFI2 Antibodies).

  5. Zn-responsive proteome profiling and time-dependent expression of proteins are regulated by MTF-1 (show MFI2 Antibodies) in human alveolar epithelial cells.

  6. The zinc-sensing cytoplasmic transcription factor MTF-1 plays a key role in cellular zinc homoeostasis.

  7. Results identify a cysteine cluster that mediates homodimerization of human MTF-1 (show MFI2 Antibodies), and show that dimer formation in vivo is important for basal and especially metal-induced transcriptional activity.

  8. Variations in the ability of LAT1 (show LAT Antibodies)/DMT1 (show DMRT1 Antibodies)/MTF1 (show MFI2 Antibodies)/MT1a (show MT1A Antibodies) to process and transport Hg may not play a significant role in the etiology of autism.

  9. It is concluded that SUMO conjugation and the SIM on MTF-1 do not play a critical role in suppressing transcriptional activity. Instead, MTF-1 forms complexes with cellular factors through SIM and SUMO moiety in the cytoplasm

  10. Transcriptional regulation of the beta-synuclein (show SNCB Antibodies) 5'-promoter metal response element by metal transcription factor-1 (show HNF1A Antibodies).

MTF1 Antigen Profile

Protein Summary

This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE).

Gene names and symbols associated with MTF1

  • metal-regulatory transcription factor 1 (MTF1) antibody
  • metal-regulatory transcription factor 1 (mtf1) antibody
  • metal-regulatory transcription factor 1 (LOC100218965) antibody
  • metal-regulatory transcription factor 1 (LOC100352804) antibody
  • metal response element binding transcription factor 1 (Mtf1) antibody
  • metal-regulatory transcription factor 1 (Mtf1) antibody
  • MGC86485 antibody
  • MTF-1 antibody
  • mtf1 antibody
  • Thyls antibody
  • ZRF antibody

Protein level used designations for MTF1

metal regulatory transcription factor 1 , metal-regulatory transcription factor 1 , metal regulatory transcription factor 1-like , MRE-binding transcription factor , metalloregulatory transcription factor , transcription factor MTF-1 , MRE-binding transcription factor-1 , metal-responsive transcription factor 1 , zinc regulatory factor , metal response element binding transcription factor 1

GENE ID SPECIES
100054605 Equus caballus
195821 Danio rerio
428218 Gallus gallus
456766 Pan troglodytes
714795 Macaca mulatta
779158 Xenopus laevis
100218965 Taeniopygia guttata
100352804 Oryctolagus cuniculus
100457400 Pongo abelii
100480003 Ailuropoda melanoleuca
100495484 Xenopus (Silurana) tropicalis
100539531 Meleagris gallopavo
100555296 Anolis carolinensis
100620000 Monodelphis domestica
17764 Mus musculus
4520 Homo sapiens
608127 Canis lupus familiaris
509960 Bos taurus
362591 Rattus norvegicus
100511998 Sus scrofa
Selected quality suppliers for anti-MTF1 (MTF1) Antibodies
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