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TIMP2 is a member of the TIMP gene family. Additionally we are shipping Metalloproteinase Inhibitor 2 Antibodies (264) and Metalloproteinase Inhibitor 2 Proteins (43) and many more products for this protein.
Showing 10 out of 77 products:
Mouse (Murine) TIMP2 ELISA Kit for Sandwich ELISA - ABIN415607
Kim, Shin, Park, Hong, Shin, Kim, Kwon, Park: Oral administration of 3,3'-diindolylmethane inhibits lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice. in The Journal of nutrition 2009
Show all 5 references for ABIN415607
Rat (Rattus) TIMP2 ELISA Kit for Sandwich ELISA - ABIN1889442
De Clerck, Szpirer, Aly, Cassiman, Eeckhout, Rousseau: The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25. in Genomics 1992
Show all 3 references for ABIN1889442
Pig (Porcine) TIMP2 ELISA Kit for Sandwich ELISA - ABIN415894
Witt, Glage, Schulz, Lichtinghagen, Simann, Pape, Sümpelmann: Impact of 6% hydroxyethyl starch 130/0.42 and 4% gelatin on renal function in a pediatric animal model. in Paediatric anaesthesia 2014
significant differences were detected concerning the activity of TIMPs resulting in a negative correlation of TIMP1 (show TIMP1 ELISA Kits) activity with MMP2 (show MMP2 ELISA Kits) activity (p = 0.044) and negative correlations of TIMP2 and TIMP3 (show TIMP3 ELISA Kits) with MMP9 (show MMP9 ELISA Kits) activity
quantitative urine test is available to assess the risk of developing AKI by measuring the concentrations of two protein biomarkers, TIMP-2 and IGFBP-7 (show IGFBP7 ELISA Kits)
Here we report isothermal titration calorimetric studies of the effects of selectivity-modifying mutations in NTIMP1 and NTIMP2 on the thermodynamics of their interactions with MMP1 (show MMP1 ELISA Kits), MMP3 (show MMP3 ELISA Kits), and MMP14 (show MMP14 ELISA Kits).
miR (show MLXIP ELISA Kits)-22 significantly upregulated the invasion capacity of 1321N1 cells. In silico analysis predicted that TIMP2 is a target gene of miR (show MLXIP ELISA Kits)-22 which was confirmed by qPCR and Western blotting. Luciferase reporter assays demonstrated that miR (show MLXIP ELISA Kits)-22 directly bound the 3'-untranslated regions of TIMP2. These data suggest that miR (show MLXIP ELISA Kits)-22 acts to regulate invasion of 1321N1 astrocytoma cells by targeting TIMP2 expression.
The expression levels MMP-9 (show MMP9 ELISA Kits), TIMP-1 (show TIMP1 ELISA Kits), and TIMP-2 in both marrow plasma and culture supernatants were significantly higher in MM patients than controls.
Pathogenesis and progression of nasal polyps is closely related with elevated MMP-9 (show MMP9 ELISA Kits) and suppressed TIMP-2 expression
our results demonstrate that TIMP-2 stimulates lung adenocarcinoma cell proliferation
new evidence that promoter polymorphisms in TIMP2 are functional and may affect gene transcription with possible effects on craniofacial development leading to NSCL (show NHLH1 ELISA Kits)/P.
This study shows that urinary [TIMP-2]*[IGFBP7 (show IGFBP7 ELISA Kits)] has a good diagnostic performance in predicting adverse outcomes in neonatal and pediatric AKI of heterogeneous etiology.
TIMP1 (show TIMP1 ELISA Kits), TIMP2, and TIMP4 (show TIMP4 ELISA Kits) are increased in aqueous humor from primary open angle glaucoma patients.
Data indicate the involvement of PKC-alpha (show PKCa ELISA Kits) in proMMP-2 activation and inhibition of TIMP-2 expression by NF-kappaB (show NFKB1 ELISA Kits)-MT1-MMP (show MMP14 ELISA Kits)-dependent and -independent pathway.
A differential pattern of matrix metalloproteinase-2 (show MMP2 ELISA Kits) and Tissue inhibitor metalloproteinase-2 was observed in cow uteri with adenomyosis.
MMP-14 (show MMP14 ELISA Kits), MMP-2 (show MMP2 ELISA Kits) and TIMP-2 are co-localized in the fetal compartment and therefore could influence the timely release of fetal membranes in cattle.
Results describe distinct changes in expression of MMP2 (show MMP2 ELISA Kits), MMP14 (show MMP14 ELISA Kits), and the metallopeptidase (show ECEL1 ELISA Kits) inhibitor TIMP2 between different phases of the estrous cycle indicating an endocrine regulation.
Production of TIMP-1 (show TIMP1 ELISA Kits) was augmented by IL-1alpha, TNFalpha (show TNF ELISA Kits), and hepatocyte growth factor (show HGF ELISA Kits) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 mRNA was not affected by any treatments.
the different temporal expression patterns of TIMP-1 (show TIMP1 ELISA Kits) and TIMP-2 suggest that TIMP-1 (show TIMP1 ELISA Kits) may be important for luteal formation and development, while TIMP-2 may play significant roles during luteal development and maintenance
Identification, purification and partial characterization of timp-2 in bovine pulmonary artery smooth muscle
Results describe the isolation of matrix metalloproteinase 2 (MMP-2 (show MMP2 ELISA Kits)) from the MMP-2 (show MMP2 ELISA Kits)/tissue inhibitor of metalloproteinase 2 (TIMP-2) complex, and the characterization of both isolated MMP-2 (show MMP2 ELISA Kits) and the complex itself.
oxidants inactivate TIMP-2, and the resulting activation of MMP-2 (show MMP2 ELISA Kits) subsequently inhibits Na+ dependent Ca2 (show CA2 ELISA Kits)+ uptake in the microsomes
TIMP-2 has a role in the pericyte-induced stabilization of newly formed vascular networks that are predisposed to undergo regression and reveal specific molecular targets of the inhibitors regulating these events.
The pathology of laminitis is associated with increased and lowered transcription of MMP-14 (show MMP14 ELISA Kits) and TIMP-2, respectively.
demonstrate that TIMP-2 plays a greater protective role than TIMP-1 (show TIMP1 ELISA Kits) during the pathogenesis of atherosclerosis
Further investigation of MMP2 (show MMP2 ELISA Kits) inhibitors of TIMP2/TIMP4 (show TIMP4 ELISA Kits) showed an upregulated TIMP2 expression, but not TIMP4 (show TIMP4 ELISA Kits). low-dose pre-radiation attenuates the skin inflammation and ROS (show ROS1 ELISA Kits) production induced by medium-dose UV radiation
TIMP2 and TIMP3 (show TIMP3 ELISA Kits) play fundamental and differential roles in mediating pathological remodelling, independent from their MMP-inhibitory function
Reduced beta(2)GP I plays a role in diabetic mice related to vascular protection, inhibiting vascular lipid deposition, and plaque formation by reducing MMPs/TIMPs expression through down-regulation of the p38MAPK (show MAPK14 ELISA Kits) signaling pathway.
High TIMP2 expression is associated with liver fibrosis.
TIMP2 promotes kidney injury through metalloproteinase (MMP)2 (show MMP2 ELISA Kits) activation
Gene expression of Mmp-12 (show MMP12 ELISA Kits) and Mmp-13 (show MMP13 ELISA Kits), and Timp-1 (show TIMP1 ELISA Kits) was strongly upregulated at all time points in RD compared with controls. Timp-2, Mmp-2 (show MMP2 ELISA Kits), and Mmp-9 (show MMP9 ELISA Kits) expression was modest.
Data indicate a significantly increased expression of type I collagen, TIMP-2, TGF-beta (show TGFB1 ELISA Kits), PAI-1 (show SERPINE1 ELISA Kits) and RAGE (show AGER ELISA Kits) in diabetic db/db (show LEPR ELISA Kits) cells.
This study suggests that miR-17 participates in the regulation of cardiac matrix remodeling and provides a novel therapeutic approach using miR-17 inhibitors to prevent remodeling and heart failure after MI.
In neural stem cells, TIMP-2 acts as key effector of the proneurogenic response to inducing stimuli such as Marimastat.
To further study the function of TIMP-2 in development, we utilized zebrafish as an experimental model system
membrane-type 1 metalloproteinase, gelatinase A (show MMP2 ELISA Kits) , and tissue inhibitor 2 of metalloproteinases mRNA transcripts were expressed in the blastema
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
, metalloproteinase inhibitor 2
, tissue inhibitor of metalloproteinase 2
, tissue inhibitor of metalloproteinases 2
, collagenase inhibitor
, tissue inhibitor of mettaloproteinase 2
, tissue inhibitor of metalloproteinase-2
, tissue inhibitor of matrix metalloproteinase-2
, metalloproteinase inhibitor TIMP-2