anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type (MMAB) Antibodies

MMAB encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Additionally we are shipping Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type Proteins (9) and Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MMAB 326625 Q96EY8
MMAB 77697 Q9D273
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC204290 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-MMAB antibody (ABIN2454035), and then analyzed by flow cytometry. Anti-MMAB mouse monoclonal antibody (ABIN2454035) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MMAB (RC204290). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC204290 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-MMAB antibody (ABIN2454109), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMAB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MMAB. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC204290 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-MMAB antibody (ABIN2454045), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMAB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MMAB. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: HepG2 12% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded human hepatoma, using MMAB, antibody at 1:500 dilution. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: MMAB Antibody [NBP2-17308] - Immunohistochemical analysis of paraffin-embedded Hepatoma, using antibody at 1:500 dilution. Western Blot: MMAB Antibody [NBP2-17308] - Sample (30 ug of whole cell lysate) A: HepG2 12% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: MMAB Antibody [NBP1-86602] - Staining of human cell line A-431 shows positivity in mitochondria. Western Blot: MMAB Antibody [NBP1-86602] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Mouse Un-conjugated FACS, IHC, IHC (p), WB Immunohistochemistry-Paraffin: MMAB Antibody (2G5) [NBP2-03417] - Staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-MMAB mouse monoclonal antibody. Flow Cytometry: MMAB Antibody (2G5) [NBP2-03417] - Analysis of Jurkat cells, using anti-MMAB antibody, (Red), compared to a nonspecific negative control antibody (Blue). 0.1 mL Log in to see 8 to 11 Days
$513.19
Details
Human Mouse Un-conjugated FACS, WB   100 μL Log in to see 7 to 9 Days
$493.17
Details

MMAB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human
,
,
Mouse (Murine)


Top referenced anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type Antibodies

  1. Human Polyclonal MMAB Primary Antibody for WB - ABIN1944767 : Dobson, Wai, Leclerc, Kadir, Narang, Lerner-Ellis, Hudson, Rosenblatt, Gravel: Identification of the gene responsible for the cblB complementation group of vitamin B12-dependent methylmalonic aciduria. in Human molecular genetics 2002 (PubMed)
    Show all 4 references for 1944767

More Antibodies against Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type Interaction Partners

Human Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type (MMAB) interaction partners

  1. These findings suggest that rs11066782 in KCTD10, rs11613718 in KCTD10 and rs11067233 in MMAB may contribute to the susceptibility of coronary heart disease by altering plasma HDL-C levels in Han Chinese.

  2. MMAB mutations, including one novel nonsense mutation (c.12 C>A [p.C4X]), were identified in all members of the cblB cohort.

  3. Pathogenicity of the human truncation mutant results from its inability to sequester AdoCbl for direct transfer to methylmalonyl-CoA mutase (show MUT Antibodies), resulting in holoenzyme formation.

  4. c.584G>A, c.349-1G>C, and c.290G>A mutations affect the splicing process of ATR.

  5. These data suggest MMAB is the most likely gene influencing high-density lipoprotein-cholesterol levels at MMAB-MVK (show MVK Antibodies) locus.

  6. Characterization of ligand-binding by MMAB provides insight into the mechanism of cobalamin adenosylation and the effect of patient mutations in the inherited disorder

  7. report the identification of ATR cDNA as well as the corresponding gene; ATR expression is altered in cell lines derived from cblB methylmalonyl aciduria patients; propose that inborn errors in the ATR gene identified here result in methylmalonyl aciduria

  8. Results describe two common polymorphic variants of ATP:cob(I)alamin adenosyltransferase that are found in normal individuals, and their interactions with methionine synthase reductase (show MTRR Antibodies).

  9. Mutations in methylmalonic aciduria type B protein is associated with methylmalonic acidemia

  10. Long-term outcome in methylmalonic acidurias is influenced by the underlying genetic defects in MCM/MMAA (show MMAA Antibodies)/MMAB.

Cow (Bovine) Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type (MMAB) interaction partners

  1. report the isolation of an ATR cDNA, from a bovine liver library, by complementation of an ATR-deficient Salmonella mutant.

Mouse (Murine) Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type (MMAB) interaction partners

  1. The mouse methylmalonic aciduria- related genes, Mmaa (show MMAA Antibodies), Mmab, and Mut (show MUT Antibodies) may have specialized functions depending on the tissue or cell type.

Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type (MMAB) Antigen Profile

Protein Summary

This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. Alternatively spliced transcript variants have been found.

Gene names and symbols associated with MMAB

  • methylmalonic aciduria (cobalamin deficiency) cblB type (MMAB) antibody
  • methylmalonic aciduria (cobalamin deficiency) type B homolog (human) (Mmab) antibody
  • 9130222L19Rik antibody
  • ATR antibody
  • cblB antibody
  • cob antibody

Protein level used designations for MMAB

ATP:cob(I)alamin adenosyltransferase , ATP:corrinoid adenosyltransferase , aquocob(I)alamin vitamin B12s adenosyltransferase , cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial , methylmalonic aciduria type B protein , cob(I)alamin adenosyltransferase , methylmalonic aciduria (cobalamin deficiency) type B , methylmalonic aciduria type B homolog , ATP:Cob(I)alamin Adenosyltransferase

GENE ID SPECIES
326625 Homo sapiens
617636 Bos taurus
77697 Mus musculus
Selected quality suppliers for anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type (MMAB) Antibodies
Did you look for something else?