MMAB antibody (Center)

Catalog No. ABIN2856429

Product Details anti-MMAB Antibody

Target: MMAB (Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type (MMAB))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMAB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse (Murine), Cow (Bovine)

Cross-Reactivity (Details): Mouse (90 %), Bovine (89 %)

Characteristics: Rabbit Polyclonal antibody to MMAB (methylmalonic aciduria (cobalamin deficiency) cblB type)
MMAB antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MMAB. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.69 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MMAB

Target: MMAB (Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type (MMAB))

Alternative Name: MMAB (MMAB Products)

Synonyms: ATR antibody, cblB antibody, cob antibody, 9130222L19Rik antibody, methylmalonic aciduria (cobalamin deficiency) cblB type antibody, methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human) antibody, MMAB antibody, Mmab antibody

Background: This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group.

Cellular Localization: Mitochondrion

Molecular Weight: 27 kDa

Gene ID: 326625