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anti-Microtubule-Actin Crosslinking Factor 1 (MACF1) Antibodies

The protein encoded by MACF1 belongs to the plakin family of cytoskeletal linker proteins. Additionally we are shipping MACF1 Kits (3) and MACF1 Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MACF1 23499 Q9UPN3
MACF1 11426  
MACF1 362587  
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Top anti-MACF1 Antibodies at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged MACF1 is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged MACF1 is approximately 1ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.45 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of MACF1 expression in transfected 293T cell line by MACF1 monoclonal antibody (M08), clone 1G9.Lane 1: MACF1 transfected lysate(10.45 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged MACF1 is 0.03 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, ELISA   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$742.50
Details
Human Rabbit Un-conjugated IHC, ELISA   50 μL Log in to see 3 to 4 Days
$510.36
Details
Mouse Rabbit FITC ICC, IF, ELISA, WB   100 μg Log in to see 1 to 2 Days
$572.00
Details
Mouse Rabbit Un-conjugated ICC, IF, ELISA, WB   100 μg Log in to see 1 to 2 Days
$485.57
Details
Human Rabbit Un-conjugated   50 μL Log in to see 9 to 19 Days
$417.00
Details

MACF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine) ,



Rat (Rattus) ,



Top referenced anti-MACF1 Antibodies

  1. Human Monoclonal MACF1 Primary Antibody for ELISA - ABIN396755 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN396755

  2. Human Polyclonal MACF1 Primary Antibody for ELISA, WB - ABIN565101 : Khositseth, Pisitkun, Slentz, Wang, Hoffert, Knepper, Yu: Quantitative protein and mRNA profiling shows selective post-transcriptional control of protein expression by vasopressin in kidney cells. in Molecular & cellular proteomics : MCP 2011 (PubMed)

  3. Human Monoclonal MACF1 Primary Antibody for ELISA - ABIN565102 : Hotta, Kawakatsu, Nakatani, Sato, Matsui, Sukezane, Akagi, Hamaji, Grigoriev, Akhmanova, Takai, Mimori-Kiyosue: Laminin-based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5alpha/beta. in The Journal of cell biology 2010 (PubMed)

More Antibodies against MACF1 Interaction Partners

Zebrafish Microtubule-Actin Crosslinking Factor 1 (MACF1) interaction partners

  1. Macf1 regulates the balbiani body and the polarity of oocyte.

Human Microtubule-Actin Crosslinking Factor 1 (MACF1) interaction partners

  1. Duplication in the microtubule-actin cross-linking factor 1 gene causes neuromuscular diseases.

  2. uncovered a role for ELMO in the recruitment of ACF7 to the membrane to promote microtubule capture and stability

  3. ACF7 targeting to the plasma membrane is both required and sufficient for microtubule capture downstream of ErbB2 (show ERBB2 Antibodies).

  4. p230 (show GOLGA4 Antibodies), through its interaction with MACF1, provides the molecular link for transport of GPI (show GNPDA1 Antibodies)-anchored proteins along the microtubule and actin cytoskeleton from the TGN (show TG Antibodies) to the cell periphery.

Mouse (Murine) Microtubule-Actin Crosslinking Factor 1 (MACF1) interaction partners

  1. Cell counting revealed significant decrease of cell proliferation and cell cycle analysis showed an S phase cell cycle arrest in MACF1-knockdown cells.

  2. Data show that microtubule actin crosslinking factor 1 (MACF1) determines neuronal positioning by regulating microtubule dynamics and mediating glycogen synthase kinase 3 (show GSK3a Antibodies) (GSK-3 (show GSK3b Antibodies)) signaling during brain development.

  3. data identify for the first time, a role for MACF1 in cardiomyocyte microtubule distribution and in adaptation to hemodynamic overload

  4. Studied ACF7 and paracellular permeability, by conditional knock out of ACF7 in the intestinal mucosa of mice. Findings indicated that ACF7 deficiency resulted in significant interstitial proliferation and columnar epithelial cell rearrangement.

  5. ACF7 is a linker protein (show LAT Antibodies) that helps to shape the cytoskeleton of the hair cell during early hair-bundle genesis.

  6. Study identified a link between GSK3beta (show GSK3b Antibodies) and ACF7 and further reveal the in vivo relevance of this connection in polarized locomotion of skin stem cells upon injury.

  7. Our data suggest a critical role for MACF1 in neuronal migration that is dependent on its ability to interact with both microfilaments and microtubules.

  8. In ACF7's absence, microtubules still bind EB1 and CLIP170, but they no longer grow along polarized actin bundles, nor do they pause and tether to actin-rich cortical sites.

  9. a new role of MACF1 in the Wnt (show WNT2 Antibodies) signaling pathway, MACF1 was highly expressed in neuronal tissues and the foregut of embryonic day 8.5 (E8.5) embryos and the head fold and primitive streak of E7.5 embryos.

  10. ACF7 deficiency compromises the targeting of microtubules along F-actin to focal adhesions (FAs), stabilizes FA-actin networks, and impairs epidermal migration.

MACF1 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the plakin family of cytoskeletal linker proteins. This protein family forms bridges between different cytoskeletal elements through specialized modular domains. The encoded protein is one of the largest size proteins identified in human cytoskeletal proteins. It has functional actin and microtubule binding domains, and it appears to stabilize actin at sites where microtubules and microfilaments meet. It may function in microtubule dynamics to facilitate actin-microtubule interactions at the cell periphery and to couple the microtubule network to cellular junctions. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene names and symbols associated with MACF1

  • microtubule-actin crosslinking factor 1 (MACF1) antibody
  • microtubule-actin crosslinking factor 1 (macf1) antibody
  • microtubule-actin crosslinking factor 1 (Macf1) antibody
  • ABP620 antibody
  • Acf7 antibody
  • Aclp7 antibody
  • DKFZp469K2016 antibody
  • fc46g01 antibody
  • MACF antibody
  • MACF1 antibody
  • mKIAA0465 antibody
  • OFC4 antibody
  • R74989 antibody
  • si:rp71-45k5.7 antibody
  • wu:fc46g01 antibody

Protein level used designations for MACF1

microtubule-actin crosslinking factor 1 , microfilament and actin filament cross-linker protein , actin-crosslinking protein , magellan , mgn , microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 , Microtubule-actin cross-linking factor 1-like , microtubule-actin cross-linking factor 1, isoforms 1/2/3/5-like , 620 kDa actin binding protein , actin cross-linking family protein 7 , macrophin 1 , microtubule-actin cross-linking factor 1 , trabeculin-alpha , actin cross-linking family 7 , actin-crosslinking protein 7 , trabeculin alpha

GENE ID SPECIES
419671 Gallus gallus
456778 Pan troglodytes
475321 Canis lupus familiaris
506730 Bos taurus
562190 Danio rerio
100025003 Monodelphis domestica
100068727 Equus caballus
100127846 Xenopus (Silurana) tropicalis
100173160 Pongo abelii
100175356 Ciona intestinalis
100341624 Oryctolagus cuniculus
100479117 Ailuropoda melanoleuca
100514848 Sus scrofa
100550622 Meleagris gallopavo
23499 Homo sapiens
11426 Mus musculus
362587 Rattus norvegicus
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