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MOCOS sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH\; MIM 607633) and aldehyde oxidase (AOX1\; MIM 602841), which is required for their enzymatic activities (Ichida et al., 2001 [PubMed 11302742]).[supplied by OMIM, Feb 2010].. Additionally we are shipping MOCOS Kits (5) and MOCOS Proteins (4) and many more products for this protein.
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Human Polyclonal MOCOS Primary Antibody for ICC, IF - ABIN4335161
Féron, Gepner, Lacassagne, Stephan, Mesnage, Blanchard, Boulanger, Tardif, Devèze, Rousseau, Suzuki, Izpisua Belmonte, Khrestchatisky, Nivet, Erard-Garcia: Olfactory stem cells reveal MOCOS as a new player in autism spectrum disorders. in Molecular psychiatry 2016
These data suggest that overexpression of LOS5/ABA3 could improve drought tolerance in transgenic soybean via enhanced abscissic acid accumulation.
Data indicate that overexpression of Arabidopsis molybdenum cofactor sulfurase gene (LOS5) in maize markedly enhanced the expression of ZmAO (show MAOB Antibodies) and aldehyde oxidase (AO (show AOX1 Antibodies)) activity, leading to abscisic acid (ABA) accumulation and increased drought tolerance.
Identification of persulfide-binding and disulfide-forming cysteine residues in the NifS (show NFS1 Antibodies)-like domain of the molybdenum cofactor sulfurase ABA3.
Overexpression of LOS5 in transgenic tobacco can enhance drought tolerance.
Mutation in Moco-sulfurase causes diminished aldehyde oxidase (show AOX1 Antibodies) and xanthine dehydrogenase (show XDH Antibodies) activities and loss of efficient chloroplast protein import.
analysis of the NifS (show NFS1 Antibodies)-like domain of ABA3 from Arabidopsis thaliana which has a role in molybdenum cofactor sulfuration
the C-terminal domain of ABA3 might act as a scaffold protein (show HOMER1 Antibodies) where prebound desulfo-molybdenum cofactor is converted into sulfurated cofactor prior to activation of aldehyde oxidase (show AOX1 Antibodies) and xanthine dehydrogenase (show XDH Antibodies).
MOCOS sulfurates the molybdenum cofactor of xanthine oxidase (XDH (show XDH Antibodies)) and aldehyde oxidase 1 (AOX1 (show AOX1 Antibodies)), which is required for their activities.
Two mutations, both in the N-terminal domain of the Human Molybdenum Cofactor Sulfurase (HMCS), were reported in patients with type II xanthinuria.
MOCOS sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH\; MIM 607633) and aldehyde oxidase (AOX1\; MIM 602841), which is required for their enzymatic activities (Ichida et al., 2001
molybdenum cofactor sulfurase
, moCo sulfurase
, molybdenum cofactor sulfurtransferase
, protein organdy
, Molybdenum cofactor sulfurase-like