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anti-Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1) Antibodies

The protein encoded by MADCAM1 is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and infl. Additionally we are shipping Mucosal Vascular Addressin Cell Adhesion Molecule 1 Kits (37) and Mucosal Vascular Addressin Cell Adhesion Molecule 1 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MADCAM1 17123  
MADCAM1 8174 Q13477
MADCAM1 54266 O70540
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Top anti-Mucosal Vascular Addressin Cell Adhesion Molecule 1 Antibodies at antibodies-online.com

Showing 10 out of 180 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, FACS, IHC (p), WB 0.2 mg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated EIA, Func, FACS, IHC (p), WB 0.5 mg Log in to see 6 to 8 Days
$632.50
Details
Human Mouse Un-conjugated EIA, FACS, IHC (p) 25 μg Log in to see 6 to 8 Days
$176.00
Details
Human Mouse PE FACS 25 Tests Log in to see 6 to 8 Days
$198.00
Details
Human Mouse Biotin EIA, FACS 25 μg Log in to see 6 to 8 Days
$253.00
Details
Human Mouse FITC FACS 0.1 mg Log in to see 6 to 8 Days
$434.50
Details
Human Mouse Un-conjugated EIA, FACS, WB 0.2 mg Log in to see 6 to 8 Days
$500.50
Details
Mouse Rat Un-conjugated FACS, IHC (fro), IP, WB 25 μg Log in to see 6 to 8 Days
$176.00
Details
Human Mouse Un-conjugated Func, EIA, IHC (fro), FACS, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$489.50
Details
Mouse Rat FITC FACS, IHC 500 μg Log in to see 3 to 4 Days
$534.64
Details

MADCAM1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Rat (Rattus) , , , ,
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Top referenced anti-Mucosal Vascular Addressin Cell Adhesion Molecule 1 Antibodies

  1. Human Monoclonal MADCAM1 Primary Antibody for EIA, FACS - ABIN120238 : Leung, Lehnert, Kanwar, Yang, Mon, McNeil, Krissansen: Bioassay detects soluble MAdCAM-1 in body fluids. in Immunology and cell biology 2004 (PubMed)
    Show all 3 references for ABIN120238

  2. Human Monoclonal MADCAM1 Primary Antibody for EIA, FACS - ABIN320242 : Leung, Greene, Ni, Raymond, Lehnert, Langley, Krissansen: Cloning of the mucosal addressin MAdCAM-1 from human brain: identification of novel alternatively spliced transcripts. in Immunology and cell biology 1997 (PubMed)
    Show all 3 references for ABIN320242

  3. Human Monoclonal MADCAM1 Primary Antibody for EIA, Func - ABIN120237 : Olloquequi, Montes, Prats, Rodríguez, Montero, García-Valero, Ferrer: Significant increase of CD57+ cells in pulmonary lymphoid follicles of COPD patients. in The European respiratory journal 2011 (PubMed)
    Show all 3 references for ABIN120237

  4. Mouse (Murine) Monoclonal MADCAM1 Primary Antibody for FACS, IHC (fro) - ABIN319645 : Briskin, McEvoy, Butcher: MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1. in Nature 1993 (PubMed)
    Show all 2 references for ABIN319645

More Antibodies against Mucosal Vascular Addressin Cell Adhesion Molecule 1 Interaction Partners

Mouse (Murine) Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1) interaction partners

  1. Nkx2-3 deficiency reprograms the endothelial addressin preference for lymphocyte homing in Peyer's patches.

  2. findings indicate that alpha4beta7*IgG can be used as a probe for functional MAdCAM-1 expressed on HEVs in GALT (show GALT Antibodies) and could potentially serve as an anti-inflammatory drug inhibiting GALT (show GALT Antibodies)-specific lymphocyte migration

  3. ectopic expression of MAdCAM-1 at the BBB (show ALMS1 Antibodies) does not increase alpha4beta7-integrin-mediated immune cell trafficking into the CNS during MOG (show MOG Antibodies)(aa35-55)-induced experimental autoimmune encephalomyelitis

  4. Observed a significant decrease in expression of ICAM-1 (show ICAM1 Antibodies) and MAdCAM-1 mRNA/protein in lactobacillus plantarum treated colitis.

  5. results suggest that AT1R (show AGTRAP Antibodies) regulates the expression of MAdCAM-1 under colonic inflammatory conditions through regulation of the translocation of NF-kappaB (show NFKB1 Antibodies) into the nucleus

  6. Lymphocyte binding to MAdCAM-1 via alpha4beta7 integrin activates a signal transduction pathway involving tyrosine phosphorylation of paxillin (show PXN Antibodies) and p105(Cas-L (show NEDD9 Antibodies))

  7. Mucosal addressin cell adhesion molecule 1 plays an unexpected role in the development of mouse guard hair.

  8. spatial heterogeneity of MAdCAM-1 and VCAM-1 (show VCAM1 Antibodies) activation following TNF-alpha (show TNF Antibodies) challenge may promote specific T lymphocyte recruitment in the inflamed colonic mucosa

  9. Increased expression of mucosal addressin cell adhesion molecule-1 in gastritis induced by Helicobacter pylori

  10. acute-graft vs host reaction was prevented when recruitment of donor T cells into Peyer's patches was interrupted by disrupting the gene encoding chemokine receptor CCR5 (show CCR5 Antibodies) or by blocking integrin alpha(4 (show ITGA4 Antibodies))beta(7)-MAdCAM-1 interactions

Human Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1) interaction partners

  1. Doxo-induced apoptosis has a role in inhibiting hepatocellular carcinoma by targeting Madcam1 and AKT (show AKT1 Antibodies) and blocking protein translation initiation

  2. MADCAM1 is up-regulated in liver cirrhosis with expression on peribiliary vascular plexus and lymphoid aggregates

  3. Domain 1 of mucosal addressin cell adhesion molecule (show MCAM Antibodies) has an I1-set fold and a flexible integrin-binding loop.

  4. Findings suggest that the inactive alpha4beta7 and alpha4beta7 activated by different stimuli have distinct conformations with different structural requirements for MAdCAM-1 binding.

  5. Ca2 (show CA2 Antibodies)+ is essential for cell tethering in flow and rolling interactions through alpha 4 integrins with MAdCAM-1 as substrate; Mg2 (show MUC7 Antibodies)+ promotes firm adhesion of cells on MAdCAM-1 but with much lower tethering efficiency in shear flow.

  6. A crystal structure for the two extracellular amino-terminal domains of human MAdCAM-1

  7. more extensive expression of MAdCAM-1 in Crohn's disease (CrD (show CRX Antibodies)), than in ulcerative colitis, which could contribute not only to mucosal inflammation, but also to transmural inflammation in CrD (show CRX Antibodies).

  8. MAdCAM-1/integrin alpha4beta7 homing system may participate in gastric inflammation in response to H pylori-infection and contributes to MALT formation, typically leading to the development of nodular gastritis.

  9. PI3-K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) is involved in the gut (show GUSB Antibodies)-specific differentiation of human intestinal microvascular endothelial cells, which results in expression of the mucosal addressin MAdCAM-1

  10. Immobilized CCL25 (show CCL25 Antibodies) and CCL28 (show ENC1 Antibodies) are both able to trigger integrin alpha(4 (show ITGA4 Antibodies))beta(7)-dependent lymphocyte arrest on MAdCAM-1 under shear flow.

Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1) Antigen Profile

Protein Summary

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.

Gene names and symbols associated with MADCAM1

  • mucosal vascular addressin cell adhesion molecule 1 (MADCAM1) antibody
  • mucosal vascular addressin cell adhesion molecule 1 (Madcam1) antibody
  • mucosal vascular addressin cell adhesion molecule 1 (MADCAM-1) antibody
  • AV211525 antibody
  • MACAM1 antibody
  • MADCAM1 antibody

Protein level used designations for MADCAM1

mucosal vascular addressin cell adhesion molecule 1 , MAdCAM-1 , mMAdCAM-1 , mucosal addressin cell adhesion molecule 1 , hMAdCAM-1 , mucosal addressin cell adhesion molecule-1 , rMAdCAM-1 , mucosal addressin cellular adhesion molecule-1

GENE ID SPECIES
789849 Bos taurus
17123 Mus musculus
8174 Homo sapiens
54266 Rattus norvegicus
100722478 Cavia porcellus
492312 Sus scrofa
485103 Canis lupus familiaris
527275 Bos taurus
100858236 Gallus gallus
654333 Ovis aries
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