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MMRN2 encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. Additionally we are shipping Multimerin 2 Kits (11) and Multimerin 2 Proteins (4) and many more products for this protein.
Showing 10 out of 26 products:
Human Polyclonal MMRN2 Primary Antibody for EIA, IHC (p) - ABIN953548
Leimeister, Steidl, Schumacher, Erhard, Gessler: Developmental expression and biochemical characterization of Emu family members. in Developmental biology 2002
Show all 2 references for ABIN953548
Human Polyclonal MMRN2 Primary Antibody for WB - ABIN949655
Noy, Lodhia, Khan, Zhuang, Ward, Verissimo, Bacon, Bicknell: Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth. in Oncogene 2015
Results suggest that CLEC14A (show CLEC14A Antibodies)-MMRN2 binding has a role in inducing sprouting angiogenesis during tumor growth, which has the potential to be manipulated in future antiangiogenic therapy design.
CLEC14A (show CLEC14A Antibodies) is a matrix component which binds to MMRN2 in the process of endothelial cells transformation in tumor angiogenesis.
MMRN2 as a crucial player in the regulation of EC function, neo-angiogenesis and hence tumor growth
Mmrn2 interacts with anthrax protective antigen.
This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6.
, elastin microfibril interfacer 3
, EMILIN-like protein EndoGlyx-1
, elastin microfibril interface located protein 3
, endoGlyx-1 p125/p140 subunit