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anti-N-Acetylglucosaminidase, alpha (NAGLU) Antibodies

NAGLU encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Additionally we are shipping N-Acetylglucosaminidase, alpha Kits (10) and N-Acetylglucosaminidase, alpha Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NAGLU 27419  
NAGLU 4669 P54802
NAGLU    
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Top anti-N-Acetylglucosaminidase, alpha Antibodies at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated WB NAGLU monoclonal antibody (M02), clone 1B7. Western Blot analysis of NAGLU expression in Jurkat. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NAGLU, antibody at 1:200 dilution. WB Image Sample(30 ug whole cell lysate) A:H1299 B:HeLa S3, C:Hep G2 , 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$396.00
Details
Rat Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$418.00
Details
Human Mouse Un-conjugated ELISA, WB NAGLU monoclonal antibody (M02), clone 1B7. Western Blot analysis of NAGLU expression in Jurkat NAGLU monoclonal antibody (M02), clone 1B7. Western Blot analysis of NAGLU expression in NIH/3T3. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB   100 μL Log in to see 5 to 7 Days
$452.81
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Mouse Rabbit Biotin ELISA   100 μg Log in to see 8 to 10 Days
$566.50
Details

NAGLU Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,
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Top referenced anti-N-Acetylglucosaminidase, alpha Antibodies

  1. Human Monoclonal NAGLU Primary Antibody for WB - ABIN394860 : Champion, Basehore, Wood, Destrée, Vannuffel, Maystadt: Identification and characterization of a novel homozygous deletion in the alpha-N-acetylglucosaminidase gene in a patient with Sanfilippo type B syndrome (mucopolysaccharidosis IIIB). in Molecular genetics and metabolism 2010 (PubMed)
    Show all 5 references for ABIN394860

More Antibodies against N-Acetylglucosaminidase, alpha Interaction Partners

Mouse (Murine) N-Acetylglucosaminidase, alpha (NAGLU) interaction partners

  1. In the 1-h test, MPS IIIB mice were hyperactive, with increased rapid exploratory behaviour and reduced immobility time.

  2. Disruption of the Naglu gene responsible for heparan sulfate degradation results in substantial changes in expression of genes related to neural cell growth and function.

  3. Our results demonstrate the advantages of intravenously administering hUCB cells into a mouse model of Sanfilippo Syndrome type B, the advantages probably a result of Naglu delivery to enzyme-deficient organs.

Human N-Acetylglucosaminidase, alpha (NAGLU) interaction partners

  1. Mutations in NAGLU gene is associated with idiopathic progressive cognitive decline.

  2. Plasma NAG correlates with gastrointestinal cancer outcomes.

  3. study reports that carriers from two families of a severe pathogenic mutation in NAGLU develop a late dominant painful axonal sensory neuropathy.

  4. A modified recombinant NAGLU fused to the receptor-binding motif of insulin-like growth factor (IGF)-II enhances its ability to enter cells using the mannose 6-phosphate receptor, which is the receptor for IGF-II at a different binding site.

  5. The research may enrich the mutation spectrum of the NAGLU gene in the Chinese population and help us further in understanding the pathogenesis of MPS IIIB.

  6. Urinary NAG/Cr may be a useful surrogate marker for renal function in ADPKD patients.

  7. This study suggests a possible role of NAGLU in susceptibility to PD while extending evidence for alpha-synuclein (show SNCA Antibodies) aggregation in the brain in lysosomal storage disorders.

  8. We have identified an 1146 bp intragenic deletion of the NAGLU gene within consanguineous parents having two children affected with Sanfilippo syndrome type B.

  9. Molecular genetics of mucopolysaccharidosis type IIIA (show SGSH Antibodies) and IIIB: Diagnostic, clinical, and biological implications

  10. Sanfilippo syndrome (subtypes A and B) in Turkey: identification of novel mutations in SGSH (show SGSH Antibodies) and NAGLU

N-Acetylglucosaminidase, alpha (NAGLU) Antigen Profile

Protein Summary

This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.

Gene names and symbols associated with NAGLU

  • N-acetylglucosaminidase, alpha (naglu) antibody
  • N-acetylglucosaminidase, alpha (NAGLU) antibody
  • alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) (Naglu) antibody
  • MPS-IIIB antibody
  • MPS3B antibody
  • NAG antibody
  • UFHSD antibody

Protein level used designations for NAGLU

N-acetylglucosaminidase, alpha , alpha-N-acetylglucosaminidase , N-acetylglucosaminidase, alpha- , alpha-N-acetylglucosaminidase-like , N-acetylglucosaminidase, alpha- (Sanfilippo disease IIIB) , N-acetyl-glucosaminidase , alpha-N-acetylglucosaminidase, lysosomal , N-acetyl-alpha-glucosaminidase

GENE ID SPECIES
560126 Danio rerio
100344181 Oryctolagus cuniculus
100479493 Ailuropoda melanoleuca
100489327 Xenopus (Silurana) tropicalis
468265 Pan troglodytes
490965 Canis lupus familiaris
707186 Macaca mulatta
27419 Mus musculus
4669 Homo sapiens
100519685 Sus scrofa
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