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anti-N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2) Antibodies

Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Additionally we are shipping ASAH2 Proteins (7) and ASAH2 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ASAH2 56624 Q9NR71
ASAH2 114104 Q91XT9
ASAH2 54447 Q9JHE3
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Top anti-ASAH2 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ASAH2 in 293 cell lysate with AP30083PU-N ASAH2 antibody at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of ASAH2 expression with Jurkat cell lysate (Lane 1, 2). 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated WB ASAH2 Antibody (C-term)  western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the ASAH2 antibody detected the ASAH2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of ASAH2 in 293 cell lysate with ASAH2 antibody at (A) 1 and (B) 2 µg/ml. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$330.00
Details

ASAH2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , ,
Rat (Rattus) ,


Mouse (Murine) ,
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Top referenced anti-ASAH2 Antibodies

  1. Human Polyclonal ASAH2 Primary Antibody for EIA, WB - ABIN499341 : Nilsson, Duan: Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract. in Chemistry and physics of lipids 2000 (PubMed)
    Show all 5 references for ABIN499341

More Antibodies against ASAH2 Interaction Partners

Human N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2) interaction partners

  1. The structural basis for ceramide recognition and hydrolysis by human neutral ceramidase has been uncovered.

  2. These results demonstrate for the first time that adiponectin (show ADIPOQ Antibodies) inhibits TNFalpha (show TNF Antibodies)-induced inflammatory response via Cav1 (show CAV1 Antibodies)-mediated ceramidase recruitment and activation in an AdipoR1 (show ADIPOR1 Antibodies)-dependent fashion.

  3. cloned a 3000 bp region upstream of the translational start site of the nCDase gene

  4. c-Jun/AP-1 (show JUN Antibodies) signaling may, in part, regulate serum-induced nCDase gene transcription

  5. Both acidic ceramidase (aCDase) and neutral ceramidase (nCDase) activities declined after low- and high-UVB, but returned to normal only in low-UVB cells

  6. Blocking acid ceramidase (show ASAH1 Antibodies) but not sphingosine kinase activity in alveolar macrophages led to decreased ERK (show EPHB2 Antibodies) and Akt (show AKT1 Antibodies) activity and induction of cell death.

  7. Neutral ceramidase is localized mainly in plasma membranes.

  8. the present study identified a novel amidase (show GATA1 Antibodies) sequence containing a critical serine residue that may function as a nucleophile in the hydrolytic attack on the amide bond present in ceramide

  9. Important for the generation of sphgosine 1 phosphqte (S1P (show MBTPS1 Antibodies)) and S1P (show MBTPS1 Antibodies)-mediated cell proliferation and survival.

  10. the purification and characterization of neutral ceramidase from human ileostomy content, using octanoyl-[(14)C]sphingosine as substrate

Mouse (Murine) N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2) interaction partners

  1. These results suggest that neutral ceramidase is a mediator of necroptosis and might be a novel therapeutic target for protection from ischaemic injury.

  2. Knocking down NCDase reduced sphingosine accumulation in mitochondria and preserved COX (show CPOX Antibodies) activity after the brain injury.

  3. Neutral ceramidase deficiency increases inflammation in a mouse model of inflammatory bowel disease.

  4. Novel pathway of ceramide production in mitochondria: thioesterase (show FASN Antibodies) and neutral ceramidase produce ceramide from sphingosine and acyl-CoA (show GNPAT Antibodies).

  5. the predicted HNF-4alpha binding site identified in the Asah2 promoter is functional

  6. molecular cloning of the mouse neutral ceramidase gene and its promoter analysis

  7. Neutral ceramidase secreted by endothelial cells is released in part associated with caveolin-1 (show CAV1 Antibodies).

  8. the Asah2-encoded neutral ceramidase is a key enzyme for the catabolism of dietary sphingolipids and regulates the levels of bioactive sphingolipid metabolites in the intestinal tract

  9. This enzyme is decreased in the small intestine in CFTR (show CFTR Antibodies) transgenic mice with a deletion in CFTR (show CFTR Antibodies)>

ASAH2 Antigen Profile

Protein Summary

Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001

Gene names and symbols associated with ASAH2

  • N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 (ASAH2) antibody
  • N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 (Asah2) antibody
  • N-acylsphingosine amidohydrolase 2 (Asah2) antibody
  • AI585898 antibody
  • BCDase antibody
  • HNAC1 antibody
  • LCDase antibody
  • N-CDase antibody
  • NCDase antibody

Protein level used designations for ASAH2

N-acylsphingosine amidohydrolase 2 , acylsphingosine deacylase 2 , mitochondrial ceramidase , neutral ceramidase , neutral/alkaline ceramidase , non-lysosomal ceramidase , N-CDase , NCDase

GENE ID SPECIES
56624 Homo sapiens
114104 Rattus norvegicus
486461 Canis lupus familiaris
54447 Mus musculus
Selected quality suppliers for anti-ASAH2 (ASAH2) Antibodies
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