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anti-N-Myc Downstream Regulated 1 (NDRG1) Antibodies

NDRG1 is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. Additionally we are shipping N-Myc Downstream Regulated 1 Proteins (16) and N-Myc Downstream Regulated 1 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NDRG1 10397 Q92597
NDRG1 299923 Q6JE36
NDRG1 17988 Q62433
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Top anti-N-Myc Downstream Regulated 1 Antibodies at antibodies-online.com

Showing 10 out of 129 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN184872 staining (0.1µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-NDRG1 Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-NDRG1 Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of NDRG1 Antibody (N-term) (ABIN390922) in MDA-MB231 cell line lysates (35 µg/lane). NDRG1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human prostate carcinoma with NDRG1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of NDRG1 Antibody (N-term) in MDA-MB231 cell line lysates (35ug/lane). NDRG1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to NDRG1 on formalin-fixed paraffin-embedded human endometrium (antibody concentration 0.7 µg/mL).  Detection limit for recombinant GST tagged NDRG1 is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$315.00
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated EIA, IHC (p), WB Immunohistochemistry Image: Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) Immunohistochemistry Image: Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-NDRG1 antibody, IHC(P) IHC(P): Human Rectal Cancer Tissue Anti-NDRG1 antibody, Western blotting Lane 1: SMMC Nucleus Cell Lysate Lane 2: SMMC Cytoplasm Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details

NDRG1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-N-Myc Downstream Regulated 1 Antibodies

  1. Human Monoclonal NDRG1 Primary Antibody for IHC (p), ELISA - ABIN393210 : Murakami, Hosoi, Izumi, Maruyama, Ureshino, Watari, Kohno, Kuwano, Ono: Identification of sites subjected to serine/threonine phosphorylation by SGK1 affecting N-myc downstream-regulated gene 1 (NDRG1)/Cap43-dependent suppression of angiogenic CXC chemokine expression in human pancreatic cancer cells. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 5 references for ABIN393210

  2. Human Polyclonal NDRG1 Primary Antibody for IHC, ELISA - ABIN184872 : Zhou, Salnikow, Costa: Cap43, a novel gene specifically induced by Ni2+ compounds. in Cancer research 1998 (PubMed)

  3. Human Polyclonal NDRG1 Primary Antibody for FACS, IHC (p) - ABIN390922 : Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications. in Molecular & cellular proteomics : MCP 2007 (PubMed)

  4. Chicken Polyclonal NDRG1 Primary Antibody for WB - ABIN2783177 : Chen, Nelson, Sadovsky: N-myc down-regulated gene 1 modulates the response of term human trophoblasts to hypoxic injury. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against N-Myc Downstream Regulated 1 Interaction Partners

Human N-Myc Downstream Regulated 1 (NDRG1) interaction partners

  1. NDRG1 inhibits stemness of colorectal cancer via down-regulation of nuclear beta-catenin (show CTNNB1 Antibodies) and CD44 (show CD44 Antibodies)

  2. Data suggest that, in colonic/prostatic neoplasm cells, increased expression of NDRG1 decreases activating phosphorylation of FAK and paxillin; silencing/inhibition of NDRG1 results in opposite effect and inhibits neoplasm cell migration/adhesion.

  3. Data indicate that N-myc downstream regulated gene 1 (NDRG1) competitively bind to glycogen synthase kinase 3beta (GSK-3beta (show GSK3b Antibodies)) and orphan nuclear receptor (Nur77 (show NR4A1 Antibodies)) to prevent beta-catenin (show CTNNB1 Antibodies) degradation.

  4. Data suggest that NDRG1 down-regulates expression and activation of HER1/EGFR (show EGFR Antibodies), HER2/ERBB2 (show ERBB2 Antibodies), and HER3/ERBB3 (show ERBB3 Antibodies) in response to epidermal growth factor (EGF (show EGF Antibodies)) ligand in pancreatic/colonic neoplasm cells.

  5. pomegranate juice-mediated decrease in cell death in hypoxia is partially mediated by NDRG1 in BeWo cells but not in primary trophoblasts.

  6. Results show that aberrant methylation of NDRG1 promoter is an important mechanism for gene silencing, playing a major role in tumor occurrence and progression of protate cancer (Pca (show FLVCR1 Antibodies)). Reversing this process may be used for PCa (show FLVCR1 Antibodies) treatment.

  7. NDRG1 could increase the resistance of neuroblastoma (show ARHGEF16 Antibodies) cells to chemotherapeutic drugs, with its positive regulation on drug resistant proteins.

  8. NDRG1 decreases phosphorylation of c-Src at Tyr416 by down-regulating EGFR expression and activation. It also affected Rac1, p130Cas, CrkII, and c-Abl. NDRG1 decreases cell migration via c-src inhibition.

  9. Overexpression of NDRG1 inhibits human glioma proliferation and invasion via phosphoinositide 3-kinase/AKT (show AKT1 Antibodies) pathways.

  10. TP53 loss leads to abnormal centrosome numbers and genomic instability mediated by NDRG1

Mouse (Murine) N-Myc Downstream Regulated 1 (NDRG1) interaction partners

  1. Using double knockout of NDR1 (show STK38 Antibodies) and 2 shows that NDRs acted downstream of MST1 (show MST1 Antibodies) to mediate the egress of mature thymocytes from the thymus, as well as the interstitial migration of naive T cells within popliteal lymph nodes.

  2. Ndrg1 is phosphorylated and degraded by CD28 (show CD28 Antibodies) signalling in a proteasome-dependent manner.

  3. Ndr1 (show STK38 Antibodies)/2-double null embryos show defects in somitogenesis and cardiac looping, which reveals their essential functions and shows that the NDR (show STK38 Antibodies) kinases are critically required during the early phase of organogenesis

  4. Rassf5 (show RASSF5 Antibodies) and Ndr1 (show STK38 Antibodies) or Ndr2 (show STK38L Antibodies) kinases regulate neuronal polarity through Par3 (show F2RL2 Antibodies) phosphorylation.

  5. NDRG1 promotes fetal growth and regulates the metabolic response to intrauterine hypoxic injury in a sexually dichotomous manner

  6. early growth response 1 (show EGR1 Antibodies), a transcription factor that binds to the NDRG1 promoter, was mediated in the NDRG1 expression regulation by PKD2 (show PKD2 Antibodies).

  7. Our findings do not support the proposed roles of NDRG1 in growth arrest, terminal differentiation, gene expression regulation and proteasomal degradation.

  8. Nickel induces HIF-1 (show HIF1A Antibodies) transactivation and Cap43 protein expression through a PI-3K/Akt (show AKT1 Antibodies)-dependent and p70(S6k (show RPS6KB1 Antibodies))-independent pathway.

  9. results indicate that NDRG1 deficiency leads to Schwann cell dysfunction, suggesting that NDRG1 is essential for maintenance of the myelin sheaths in peripheral nerves

  10. NDRG1 may play an important role in the terminal differentiation of Schwann cells during nerve regeneration.

Arabidopsis thaliana N-Myc Downstream Regulated 1 (NDRG1) interaction partners

  1. NDR1 plays a broad role both in mediating primary cellular functions in Arabidopsis through maintaining the integrity of the cell wall-plasma membrane connection and as a key signaling component of these responses during pathogen infection.

  2. SR1 plays an important role in plant immunity and ethylene signaling by directly regulating NDR1 and EIN3.

  3. The induction of defence responses and disease resistance to X. campestris pv. campestris strain 8004 requires NDR1 , RAR1 and SGT1b, suggesting that effector-triggered immunity plays a large role in resistance to this strain.

  4. Sequence analysis and mass spectrometry suggest that NDR1 (show STK38 Antibodies) is localized to the PM via a C-terminal glycosylphosphatidyl-inositol (GPI (show GPI Antibodies)) anchor.

  5. demonstrate that the RIN4-NDR1 interaction occurs on the cytoplasmically localized N-terminal portion of NDR1 and that this interaction is required for the activation of resistance signaling following infection by P. syringae

  6. Mutations in NDR1 (show STK38 Antibodies) abolished the enhanced resistance of dnd (show DND1 Antibodies) mutants against Pseudomonas syringae pv. tomato and Hyaloperonospora parasitica but not Botrytis cinerea.

N-Myc Downstream Regulated 1 (NDRG1) Antigen Profile

Protein Summary

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with NDRG1

  • N-myc downstream regulated 1 (NDRG1) antibody
  • N-myc downstream regulated 1 (ndrg1-b) antibody
  • N-myc downstream regulated 1 (Ndrg1) antibody
  • N-myc downstream regulated gene 1 (Ndrg1) antibody
  • N-myc downstream regulated gene 1a (ndrg1a) antibody
  • protein NDR1 (NDR1) antibody
  • cap43 antibody
  • cb775 antibody
  • cmt4d antibody
  • DRG-1 antibody
  • drg1 antibody
  • gc4 antibody
  • hmsnl antibody
  • Ndr1 antibody
  • ndrg1 antibody
  • Ndrl antibody
  • nmsl antibody
  • NON-RACE SPECIFIC DISEASE RESISTANCE PROTEIN antibody
  • non race-specific disease resistance 1 antibody
  • proxy1 antibody
  • rit42 antibody
  • rtp antibody
  • targ1 antibody
  • tdd5 antibody
  • wu:fb60h02 antibody
  • xndrg1 antibody
  • zgc:63944 antibody

Protein level used designations for NDRG1

N-myc downstream regulated gene 1 , N-myc downstream regulated 1 , N-myc downstream-regulated gene 1 protein , differentiation-related gene 1 protein , nickel-specific induction protein Cap43 , protein NDRG1 , protein regulated by oxygen-1 , reducing agents and tunicamycin-responsive protein , protein NDRG1-B , xNDRG1-B , protein Ndr1

GENE ID SPECIES
100068997 Equus caballus
697752 Macaca mulatta
482049 Canis lupus familiaris
10397 Homo sapiens
380319 Xenopus laevis
420321 Gallus gallus
504499 Bos taurus
299923 Rattus norvegicus
464411 Pan troglodytes
17988 Mus musculus
792085 Danio rerio
821607 Arabidopsis thaliana
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