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NAD(P) Dependent Steroid Dehydrogenase-Like Proteins (NSDHL)

The protein encoded by NSDHL is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Additionally we are shipping NAD(P) Dependent Steroid Dehydrogenase-Like Antibodies (23) and NAD(P) Dependent Steroid Dehydrogenase-Like Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NSDHL 50814 Q15738
NSDHL 18194 Q9R1J0
Rat NSDHL NSDHL 309262 Q5PPL3
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Top NAD(P) Dependent Steroid Dehydrogenase-Like Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$388.93
Details

NSDHL Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for NAD(P) Dependent Steroid Dehydrogenase-Like (NSDHL) Interaction Partners

Human NAD(P) Dependent Steroid Dehydrogenase-Like (NSDHL) interaction partners

  1. Here we present the case of a 9-year-old Chinese girl born with the typical clinical features of CHILD syndrome. Evaluation of the skin lesions confirmed the diagnosis and led to identification of a heterozygous point mutation in exon 8 of the NSDHL gene.

  2. Our findings expand the spectrum of mutations in NSDHL in CHILD syndrome, and indicate that large exon deletions may be not rare.

  3. A novel missense mutation in the NSDHL gene identified in a Lithuanian family by targeted next-generation sequencing causes CK syndrome.

  4. human NSDHL protein and mouse Nsdhl mRNA were expressed in tissues synthesizing cholesterol and steroids and in all peripheral tissues affected by CHILD or CK syndromes.

  5. found that males with intellectual disability in another reported family with an NSDHL mutation (c.1098 dup [p.Arg367SerfsX33]) have CKS

  6. The missense mutation of the NSDHL gene is detected in CHILD syndrome.

  7. Lethality of Nsdhl deficient mouse embryos is rescued by transgenic mice expressing human Nsdhl.

  8. NAD(P)H (show NQO1 Proteins) steroid dehydrogenase-like protein (show HSDL1 Proteins) is localized to lipid droplets

  9. NSDHL, an enzyme involved in cholesterol synthesis, traffics through the Golgi and accumulates on ER membranes and on the surface of lipid droplets.

  10. microarray analysis of gene expression related to NSDHL sterol dehydrogenase in embryonic fibroblasts

Mouse (Murine) NAD(P) Dependent Steroid Dehydrogenase-Like (NSDHL) interaction partners

  1. The role of NSDHL and cholesterol in postnatal central nervous system development is shown.

  2. A novel SNP in Nsdhl suggests that Nsdhl is the causal gene for the HDL (show HSD11B1 Proteins) level QTL.

  3. This work identifies a critical role for SC4MOL (show MSMO1 Proteins) and NSDHL in the regulation of EGFR (show EGFR Proteins) signaling and endocytic trafficking and suggests novel strategies to increase the potency of EGFR (show EGFR Proteins) antagonists in tumors

  4. Lethality of Nsdhl deficient mouse embryos is rescued by transgenic mice expressing human Nsdhl.

  5. While NSDHL-deficient cells in the mosaic Bpa (show DST Proteins)(1H) female are able to survive and differentiate during embryonic development, they are subject to negative selection over the life of the animal.

  6. implicate the hedgehog (show SHH Proteins) signaling pathway in the pathogenesis of the placental defects in NSDHL deficiency

NAD(P) Dependent Steroid Dehydrogenase-Like (NSDHL) Protein Profile

Protein Summary

The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene.

Gene names and symbols associated with NSDHL

  • NAD(P) dependent steroid dehydrogenase-like (NSDHL)
  • NAD(P) dependent steroid dehydrogenase-like (nsdhl)
  • NAD(P) dependent steroid dehydrogenase-like (Nsdhl)
  • AI747449 protein
  • Bpa protein
  • H105E3 protein
  • SDR31E1 protein
  • Str protein
  • XAP104 protein
  • zgc:112474 protein

Protein level used designations for NSDHL

sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating , protein H105e3 , short chain dehydrogenase/reductase family 31E, member 1 , bare patches , striated

GENE ID SPECIES
100063648 Equus caballus
550369 Danio rerio
496236 Xenopus laevis
422302 Gallus gallus
50814 Homo sapiens
481079 Canis lupus familiaris
100157894 Sus scrofa
616694 Bos taurus
18194 Mus musculus
309262 Rattus norvegicus
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