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anti-NIMA-Related Kinase 1 (NEK1) Antibodies

The protein encoded by NEK1 is a serine/threonine kinase involved in cell cycle regulation. Additionally we are shipping NEK1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NEK1 18004 P51954
NEK1 4750 Q96PY6
NEK1 290705  
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Top anti-NEK1 Antibodies at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Hamster Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Hamster Rabbit Un-conjugated IHC (p), WB The anti-NEK1 Pab (ABIN392648) is used in Western blot to detect NEK1 in CHO cell lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Hamster Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC (p), WB   400 μL Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

NEK1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,


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Human , ,


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Rat (Rattus) , ,


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Top referenced anti-NEK1 Antibodies

  1. Hamster Polyclonal NEK1 Primary Antibody for EIA, IHC (p) - ABIN360536 : Surpili, Delben, Kobarg: Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1. in Biochemistry 2003 (PubMed)
    Show all 3 references for ABIN360536

  2. Hamster Polyclonal NEK1 Primary Antibody for IHC (p), WB - ABIN392648 : Letwin, Mizzen, Motro, Ben-David, Bernstein, Pawson: A mammalian dual specificity protein kinase, Nek1, is related to the NIMA cell cycle regulator and highly expressed in meiotic germ cells. in The EMBO journal 1992 (PubMed)
    Show all 2 references for ABIN392648

More Antibodies against NEK1 Interaction Partners

Mouse (Murine) NIMA-Related Kinase 1 (NEK1) interaction partners

  1. Nek1 is detectable in all murine tissues but its expression in wild type and kat2J heterozygous kidneys decrease as the kidneys mature. In the embryonic kidney, Nek1 expression is most prominent in cells that will become podocytes and proximal tubules.

  2. results demonstrate that Nek1 is important for proper checkpoint control and characterize for the first time a DNA damage response that does not directly involve one of the known upstream mediator kinases, ATM or ATR

  3. data suggest that TAZ (show TAZ Antibodies) and Nek1 constitute a negative feedback loop linked through phosphorylation and ubiquitination and that the interaction of Nek1 and TAZ (show TAZ Antibodies) maintain polycystin 2 (show PKD2 Antibodies) at the level needed for proper ciliogenesis

  4. NEK1 is required for the maintenance of genome stability by acting at multiple junctures, including control of chromosome stability

  5. Nek1 may function as a kinase early in the DNA damage response pathway.

  6. Murine NIMA-related kinase, Nek1, is larger than previously reported, and that the full-length protein conserves the structural hallmarks of NIMA

  7. Nek1 links cell cycle progression and the primary cilium cycle.

  8. we propose that Nek1 plays a role in centrosome integrity, affecting both ciliogenesis and centrosome stability

  9. These data show that Nek1 is important for efficient DNA damage checkpoint control and for proper DNA damage repair.

  10. NEK1 is a candidate to transduce messages from the ciliary-basal body region to the regulation of nuclear gene expression.

Human NIMA-Related Kinase 1 (NEK1) interaction partners

  1. C21ORF2 (show C21orf2 Antibodies) functions in the same pathway as NEK1 in DNA damage repair.

  2. Nek1 may facilitate S-phase progression by interacting with Ku80 (show XRCC5 Antibodies) and regulating chromatin loading of replication factors.

  3. Nek1 may suppress cilia by phosphorylating pVHL (show VHL Antibodies), which is critical to microtubule stabilization and ciliary stability.

  4. as an ATR (show ANTXR1 Antibodies)-associated kinase, Nek1 enhances the stability and activity of ATR (show ANTXR1 Antibodies)-ATRIP (show ATRIP Antibodies) before DNA damage, priming ATR (show ANTXR1 Antibodies)-ATRIP (show ATRIP Antibodies) for a robust DNA damage response

  5. The present case provides evidence for a correlation of NEK1 mutation with short rib-polydactyly syndrome type II (Majewski.

  6. This study confirms that NEK1 is one gene causing SRP type II but also reports mutations in DYNC2H1, expanding the phenotypic spectrum of DYNC2H1 mutations.

  7. results demonstrate that Nek1 is important for proper checkpoint control and characterize for the first time a DNA damage response that does not directly involve one of the known upstream mediator kinases, ATM or ATR

  8. absence of functional full-length NEK1 severely reduces cilia number and alters ciliar morphology in vivo.

  9. Nek1 is involved in the beginning of the cellular response to genotoxic stress and plays an important role in preventing cell death induced by DNA damage.

  10. Data report that NEK1 and CLASP2 (show CLASP2 Antibodies) colocalize with FEZ1 (show LZTS1 Antibodies) in a perinuclear region in mammalian cells, and observed that coiled-coil interactions occur between FEZ1 (show LZTS1 Antibodies)/CLASP2 (show CLASP2 Antibodies) and FEZ1 (show LZTS1 Antibodies)/NEK1 in vitro.

NEK1 Antigen Profile

Protein Summary

The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NEK1

  • NIMA (never in mitosis gene a)-related expressed kinase 1 (Nek1) antibody
  • NIMA (never in mitosis gene a)-related kinase 1 (NEK1) antibody
  • NIMA-related kinase 1 (NEK1) antibody
  • NIMA-related kinase 1 (Nek1) antibody
  • serine/threonine-protein kinase Nek1 (NEK1) antibody
  • ATNEK1 antibody
  • D8Ertd790e antibody
  • F20D21.32 antibody
  • F20D21_32 antibody
  • kat antibody
  • NIMA-RELATED KINASE1 antibody
  • NIMA-related serine/threonine kinase 1 antibody
  • NY-REN-55 antibody
  • SRPS2 antibody
  • SRPS2A antibody

Protein level used designations for NEK1

NIMA-related kinase 1 , NY-REN-55 antigen , Nek1 serine/threonine- and tyrosine-specific protein kinase , kidney, anemia and testis , never in mitosis A-related kinase 1 , nimA-related protein kinase 1 , serine/threonine-protein kinase Nek1 , NIMA (never in mitosis gene a)-related kinase 1 , protein-serine/threonine kinase , renal carcinoma antigen NY-REN-55 , NIMA (never in mitosis gene a)-related expressed kinase 1

GENE ID SPECIES
18004 Mus musculus
486058 Canis lupus familiaris
4750 Homo sapiens
534671 Bos taurus
290705 Rattus norvegicus
841893 Arabidopsis thaliana
Selected quality suppliers for anti-NEK1 (NEK1) Antibodies
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