Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
NLRP3 encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. Additionally we are shipping NLRP3 Kits (6) and NLRP3 Proteins (4) and many more products for this protein.
Showing 10 out of 201 products:
Human Monoclonal NLRP3 Primary Antibody for FACS, ICC - ABIN4898963
Hu, Zhang, Wang, Mao, Lv, Yuan, Huang, Ding, Xie, Liu: Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light. in Cell death & disease 2016
Show all 6 references for ABIN4898963
Human Polyclonal NLRP3 Primary Antibody for IHC, IHC (p) - ABIN4340115
Abdul-Sater, Koo, Häcker, Ojcius: Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis. in The Journal of biological chemistry 2009
Show all 5 references for ABIN4340115
Human Polyclonal NLRP3 Primary Antibody for IF (p), IHC (p) - ABIN1386361
Zendedel, Johann, Mehrabi, Joghataei, Hassanzadeh, Kipp, Beyer: Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model. in Molecular neurobiology 2015
Show all 4 references for ABIN1386361
Human Monoclonal NLRP3 Primary Antibody for IHC, IHC (fro) - ABIN4340117
Shio, Tiemi Shio, Eisenbarth, Savaria, Vinet, Bellemare, Harder, Sutterwala, Bohle, Descoteaux, Flavell, Olivier: Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. in PLoS pathogens 2009
Show all 3 references for ABIN4340117
Human Polyclonal NLRP3 Primary Antibody for ICC, IF - ABIN2506713
Saitoh, Tsutsumi, Tada, Ikeda, Noguchi: Recurrent primary leptomeningeal astrocytoma of the lumbosacral spinal cord resembling schwannoma. A case report. in Acta pathologica japonica 1989
Show all 2 references for ABIN2506713
Human Polyclonal NLRP3 Primary Antibody for IHC (p), WB - ABIN652504
Jhang, Lu, Ho, Cheng, Yen: Protective Effects of Catechin against Monosodium Urate-Induced Inflammation through the Modulation of NLRP3 Inflammasome Activation. in Journal of agricultural and food chemistry 2015
Show all 2 references for ABIN652504
Human Polyclonal NLRP3 Primary Antibody for IHC, ELISA - ABIN185676
Kanneganti, Ozören, Body-Malapel, Amer, Park, Franchi, Whitfield, Barchet, Colonna, Vandenabeele, Bertin, Coyle, Grant, Akira, Núñez: Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. in Nature 2006
Human Polyclonal NLRP3 Primary Antibody for EIA, WB - ABIN453768
Feldmann, Prieur, Quartier, Berquin, Certain, Cortis, Teillac-Hamel, Fischer, de Saint Basile: Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. in American journal of human genetics 2002
Cow (Bovine) Polyclonal NLRP3 Primary Antibody for EIA, FACS - ABIN569576
Hoffman, Mueller, Broide, Wanderer, Kolodner: Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. in Nature genetics 2001
NLRP3 (rs4612666) single-nucleotide polymorphisms with ageing and/or smoking habit potentially might play a significant role in the pathogenic pathways of periodontal disease.
Levels of NLRP3 and IL1beta (show IL1B Antibodies) were positively correlated with adipocyte diameter in male, but not in female cancer patients.
High expression of NLRP3, NLRC4 (show NLRC4 Antibodies), and CASP1 (show CASP1 Antibodies) in background non-tumorous liver is significantly correlated with poor prognosis of patients after resection of hepatocellular carcinoma.
identical amino acid substitutions related to NLRP3 mutations are known to be sometimes associated with different phenotype suggesting the involvement of additional genetic and environmental factors
Results indicate that NLRP3 inflammasome plays a vital role in regulating the proliferation and migration of A549 lung cancer cells.
Our findings for the first time show that the NLRP3 rs10754558 polymorphism is involved in the occurrence of CAD (show CAD Antibodies) in the Chinese Han population; and G allele can effectively predict clinical outcome of CAD (show CAD Antibodies). The G allele susceptibility to CAD (show CAD Antibodies) is maybe associated with the increased level of serum IL-1b (show IL1B Antibodies).
We now show that ADAM10 (show ADAM10 Antibodies) is critical for alpha-hemolysin (show PLC Antibodies)-mediated activation of the NLRP3 inflammasome in human monocytes as siRNA knockdown or chemical blockade of ADAM10 (show ADAM10 Antibodies)-alpha-hemolysin (show PLC Antibodies) interaction leads to diminished inflammasome activation and cell death by reducing the available ADAM10 (show ADAM10 Antibodies) on the cell surface.
There is a significant association between rs3806268 in NLRP3 gene and the risk of primary gout in a Chinese population.
the NLRP3 inflammasome is dysregulated in idiopathic pulmonary fibrosis but not in rheumatoid arthritis-usual interstitial pneumonia
The NLRP3 rs3806265 T allele was significantly more frequent in the patients with RAS than in the healthy controls.
Ambient fine particulate matter-induced myocarditis is mediated by EGFR (show EGFR Antibodies)/Akt (show AKT1 Antibodies) signaling and overexpression of NLRP3 and NLRP12 (show NLRP12 Antibodies).
Hepatic NLRP3 inflammasome activation played an important role in the development of non-alcoholic fatty liver disease via relA (show NFkBP65 Antibodies) phosphorylation.
NMDAR1 (show GRIN1 Antibodies) plays a pivotal role in hemin-induced NLRP3-mediated inflammatory damage through synergistic activation.
Renal medullary Nlrp3 inflammasomes regulate renal medullary blood flow and sodium excretion.
our study demonstrated that ablating the NLRP3 gene significantly reduced neuroinflammation and delayed RGC loss after optic nerve crush injury.
Data show that NLR family pyrin domain containing 3 (Nlrp3) gene silencing abolished the visfatin (show NAMPT Antibodies)-induced high mobility group box (show SSRP1 Antibodies) protein 1 (HMGB1 (show HMGB1 Antibodies)) release from vascular endothelial cell (MVEC).
Sertoli cells have a functional NALP3 inflammasome that modulates NOD1 (show NOD1 Antibodies) and pro-IL-1beta (show IL1B Antibodies) expression, while NOD2 (show NOD2 Antibodies) inversely promoted IL-1beta (show IL1B Antibodies) expression.
Melatonin also attenuated the expressions of NLRP3, apoptosis-associated speck-like protein containing a caspase (show CASP3 Antibodies) recruitment domain (ASC (show STS Antibodies)), cleaved caspase-1 (show CASP1 Antibodies), interleukin-1beta (IL-1beta (show IL1B Antibodies)), and interleukin-6 (IL-6 (show IL6 Antibodies)); these changes were also associated with an increase in the anti-apoptotic factor (Bcl2 (show BCL2 Antibodies)) and reduction in the pro-apoptotic factor (Bim (show BCL2L11 Antibodies)).
Poly-ADP-ribosylation-mediated degradation of ARTD1 (show PARP1 Antibodies) by the NLRP3 inflammasome is a prerequisite for osteoclast maturation.
provides a direct link between miR-7 (show LILRB1 Antibodies) and NLRP3 inflammasome-mediated neuroinflammation in the pathogenesis of Parkinson's disease
This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.
NACHT, LRR and PYD domains-containing protein 3
, cold autoinflammatory syndrome 1
, NLR family, pyrin domain containing 3
, NACHT, LRR and PYD domains-containing protein 3-like
, NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3
, NACHT, LRR and PYD containing protein 3
, PYRIN-containing APAF1-like protein 1
, caterpiller protein 1.1
, cold autoinflammatory syndrome 1 protein
, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3
, NACHT/LRR/pyrin domain-containing protein 3
, cold autoinflammatory syndrome 1 homolog
, cold autoinflammatory syndrome 1 protein homolog
, mast cell maturation inducible protein 1
, mast cell maturation-associated-inducible protein 1
, NLR family pyrin domain containing 3