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anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) Antibodies

NLRP3 encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. Additionally we are shipping NLRP3 Kits (6) and NLRP3 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NLRP3 114548 Q96P20
NLRP3 216799 Q8R4B8
NLRP3 287362  
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Top anti-NLRP3 Antibodies at antibodies-online.com

Showing 10 out of 168 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of NLRP3 Antibody (N-term) (ABIN652504) in MDA-M... NLRP3 Antibody (N-term) (ABIN652504) immunohistochemistry analysis in ... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated EIA, FACS AP22372PU-N NLRP3 antibody staining of Formalin-Fixed, Paraffin-Embedd... 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of NLRP3 Antibody (N-term) in MDA-MB231 cell lin... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunofluorescence of NALP3 in K562 cells with NALP3 antibody at 20 μg... Western blot analysis of NALP3 in K562 cell lysate with NALP3 antibody... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:400... Formalin-fixed and paraffin embedded human lung carcinoma labeled with... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB Immunohistochemical staining of rat skin tissue using Cryopyrin antibo... IHC-P staining of human  thyroid carcinoma tissue using anti-Cryopyrin... 100 μg Log in to see 9 to 14 Days
$351.12
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-CIAS1/NALP3 antibody, IHC(P) IHC(P): Human Tonsil Tissue Anti-CIAS1/NALP3 antibody, Western blotting Lane 1: HEP-2 Cell Lysate ... 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB Observed bind size: 118KD Anti-CIAS1/NALP3 Picoband antibody,  All lanes: Anti CIAS1  at 0.5ug/m... 100 μg Log in to see 4 to 6 Days
$240.00
Details

NLRP3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-NLRP3 Antibodies

  1. Human Polyclonal NLRP3 Primary Antibody for EIA, IF - ABIN500314 : OConnor, Harton, Zhu, Linhoff, Ting: Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 5 references for ABIN500314

  2. Human Polyclonal NLRP3 Primary Antibody for ICC, IF - ABIN2506713 : Saitoh, Tsutsumi, Tada, Ikeda, Noguchi: Recurrent primary leptomeningeal astrocytoma of the lumbosacral spinal cord resembling schwannoma. A case report. in Acta pathologica japonica 1989 (PubMed)
    Show all 2 references for ABIN2506713

  3. Human Polyclonal NLRP3 Primary Antibody for IF (p), IHC (p) - ABIN1386361 : Zendedel, Johann, Mehrabi, Joghataei, Hassanzadeh, Kipp, Beyer: Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model. in Molecular neurobiology 2015 (PubMed)
    Show all 2 references for ABIN1386361

  4. Cow (Bovine) Polyclonal NLRP3 Primary Antibody for EIA, FACS - ABIN569576 : Hoffman, Mueller, Broide, Wanderer, Kolodner: Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. in Nature genetics 2001 (PubMed)

  5. Human Polyclonal NLRP3 Primary Antibody for EIA, WB - ABIN453768 : Feldmann, Prieur, Quartier, Berquin, Certain, Cortis, Teillac-Hamel, Fischer, de Saint Basile: Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. in American journal of human genetics 2002 (PubMed)

  6. Human Polyclonal NLRP3 Primary Antibody for IHC, ELISA - ABIN185676 : Kanneganti, Ozören, Body-Malapel, Amer, Park, Franchi, Whitfield, Barchet, Colonna, Vandenabeele, Bertin, Coyle, Grant, Akira, Núñez: Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. in Nature 2006 (PubMed)

  7. Human Polyclonal NLRP3 Primary Antibody for IHC (p), WB - ABIN652504 : Jhang, Lu, Ho, Cheng, Yen: Protective Effects of Catechin against Monosodium Urate-Induced Inflammation through the Modulation of NLRP3 Inflammasome Activation. in Journal of agricultural and food chemistry 2015 (PubMed)

More Antibodies against NLRP3 Interaction Partners

Human NLR Family, Pyrin Domain Containing 3 (NLRP3) interaction partners

  1. NLRP3 inflammasome in subcutaneous adipose tissue may have a role in atherogenesis

  2. NLRP3 polymorphism may have a role in diabetic macrovascular complications, especially in myocardial infarction

  3. NLRP3 expression, and not the inflammasome activation, is required for epithelial-mesenchymal transition in colorectal cancer cells.

  4. These results demonstrated that the close relationship between the expression of NLRP3 signaling pathway and human carotid atherosclerotic plaques.

  5. role of the influenza virus NS1 (show PTPN11 Antibodies) protein in activating the NLRP3 inflammasome

  6. NALP3 inflammasome is expressed in the inflammatory periapical tissues. This cytokine-signalling pathway may therefore be crucial in the regulatory control of inflammatory responses in periapical tissues and the development of periapical lesions

  7. PPARgamma (show PPARG Antibodies) prevented NALP3 inflammasome formation and IL1beta (show IL1B Antibodies) production in HK2 (show HK2 Antibodies) cells stimulated by monosodium urate crystals

  8. Results suggest that astroglial NLRP3 inflammasome complexes are critically involved in neuroinflammation in amyotrophic lateral sclerosis

  9. Caspase-1 (show CASP1 Antibodies) inhibition significantly reduced IL-1beta (show IL1B Antibodies) secretion induced by all stimuli, whereas caspase-8 (show CASP8 Antibodies) inhibition affected only TLR4 (show TLR4 Antibodies) and TLR3 (show TLR3 Antibodies) cell priming

  10. While both contributing to pathogen clearance, NLRP3 more than NLRC4 (show NLRC4 Antibodies) contributes to deleterious inflammatory responses in cystic fibrosis (show S100A8 Antibodies) and correlates with defective NLRC4 (show NLRC4 Antibodies)-dependent IL-1Ra (show IL1RN Antibodies) production.

Mouse (Murine) NLR Family, Pyrin Domain Containing 3 (NLRP3) interaction partners

  1. Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 (show IL10 Antibodies) Mediated Regulation of NLRP3 Expression and Caspase-8 (show CASP8 Antibodies) Activation

  2. While both contributing to pathogen clearance, NLRP3 more than NLRC4 (show NLRC4 Antibodies) contributes to deleterious inflammatory responses in cystic fibrosis (show S100A8 Antibodies) and correlates with defective NLRC4 (show NLRC4 Antibodies)-dependent IL-1Ra (show IL1RN Antibodies) production.

  3. The pro-inflammatory and cancer-promoting effects of a high cholesterol diet are mediated by the activation of NLRP3.

  4. Results suggest that astroglial NLRP3 inflammasome complexes are critically involved in neuroinflammation in amyotrophic lateral sclerosis

  5. that generation of reactive oxygen species and potassium efflux contribute to HIV-induced pyroptosis and NLRP3 inflammasome activation in podocytes

  6. Data (including data from studies in knockout mice) suggest NLRP3 is not required for activation of macrophages and dendritic cells by soluble saponin adjuvant, QS-21, in mice immunized with HIV-1 glycoprotein 120 subunit vaccine.

  7. Rotavirus infection in macrophages depend on MAVS (show MAVS Antibodies) but not involve the NLRP3 inflammasome nor JNK (show MAPK8 Antibodies) and p38 (show CRK Antibodies) signal pathway.

  8. Ferric ammonium citrate consistently induced interleukin-1beta secretion in THP1 (show GLI2 Antibodies) cells, but not in NLRP3-deficient THP1 (show GLI2 Antibodies) cells, indicating a requirement for the NLRP3 inflammasome

  9. NLRP3 is critically involved in development of bronchopulmonary dysplasia. In response to hyperoxia, Nlrp3(-/-) mice have no caspase-1 (show CASP1 Antibodies) activity, no IL1beta (show IL1B Antibodies), no inflammatory response and undergo normal alveolarization.

  10. Our data imply that NLRP3 contributes to cardio-protection during I/R and do not support a role for NLRP3 or ASC (show STS Antibodies) inhibition in the management of acute MI including revascularization therapy.

NLRP3 Antigen Profile

Protein Summary

This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.

Gene names and symbols associated with NLRP3

  • NLR family, pyrin domain containing 3 (NLRP3) antibody
  • NLR family, pyrin domain containing 3 (LOC100351623) antibody
  • NLR family, pyrin domain containing 3 (nlrp3) antibody
  • NLR family, pyrin domain containing 3 (Nlrp3) antibody
  • AGTAVPRL antibody
  • AII antibody
  • AII/AVP antibody
  • AVP antibody
  • C1orf7 antibody
  • Cias1 antibody
  • CLR1.1 antibody
  • FCAS antibody
  • FCU antibody
  • Mmig1 antibody
  • MWS antibody
  • NALP3 antibody
  • Pypaf1 antibody

Protein level used designations for NLRP3

NACHT, LRR and PYD domains-containing protein 3 , cold autoinflammatory syndrome 1 , cryopyrin , NLR family, pyrin domain containing 3 , NACHT, LRR and PYD domains-containing protein 3-like , NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3 , NACHT, LRR and PYD containing protein 3 , PYRIN-containing APAF1-like protein 1 , caterpiller protein 1.1 , cold autoinflammatory syndrome 1 protein , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 , NACHT/LRR/pyrin domain-containing protein 3 , cold autoinflammatory syndrome 1 homolog , cold autoinflammatory syndrome 1 protein homolog , mast cell maturation inducible protein 1 , mast cell maturation-associated-inducible protein 1 , NLR family pyrin domain containing 3

GENE ID SPECIES
423021 Gallus gallus
469743 Pan troglodytes
490576 Canis lupus familiaris
100351623 Oryctolagus cuniculus
100381165 Xenopus laevis
100392399 Callithrix jacchus
114548 Homo sapiens
216799 Mus musculus
538639 Bos taurus
287362 Rattus norvegicus
701278 Macaca mulatta
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