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The protein encoded by NSMF is involved in guidance of olfactory axon projections and migration of luteinizing hormone-releasing hormone neurons. Additionally we are shipping NMDA Receptor Synaptonuclear Signaling and Neuronal Migration Factor Antibodies (50) and NMDA Receptor Synaptonuclear Signaling and Neuronal Migration Factor Kits (3) and many more products for this protein.
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The nuclear and non-nuclear NELF (show NELF Proteins) variant transcripts and proteins were identified, explaining variable NELF (show NELF Proteins) cellular localization.
a model in which NELF recruits Pcf11 and NCoR1-GPS2-HDAC3 to paused RNAP II, reinforcing repression of HIV transcription and establishing a critical checkpoint for HIV transcription and latency.
NELF (show NELF Proteins) is associated with normosmic idiopathic hypogonadotropic hypogonadism and Kallmann syndrome, either singly or in combination with a mutation in another gene.
our findings implicate NELF as a nuclear protein involved in the developmental function of the reproductive axis.
12% of Kallman syndrome males have KAL1 (show KAL1 Proteins) deletions, but intragenic deletions of the FGFR1 (show FGFR1 Proteins), GNRH1 (show GNRH1 Proteins), GNRHR (show GNRHR Proteins), GPR54 and NELF (show NELF Proteins) genes are uncommon in Idiopathic hypogonadotropic hypogonadism/Kallman syndrome.
The protein encoded by this gene is involved in guidance of olfactory axon projections and migration of luteinizing hormone-releasing hormone neurons. Defects in this gene are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Several transcript variants encoding different isoforms have been found for this gene.
nasal embryonic LHRH factor
, nasal embryonic luteinizing hormone-releasing hormone factor