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N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. Additionally we are shipping NSFL1C Proteins (6) and many more products for this protein.
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p47 (show ING1 Antibodies) promotes, whereas SASK1 delays the degradation of a single ERAD substrate, alpha-TCR. Additionally, we found that SAKS1 (show UBXN1 Antibodies) selectively inhibits the degradation of ERAD substrates without affecting cytosolic proteasomal substrates.
The present results for the first time demonstrate that BDNF (show BDNF Antibodies) induces NADPH oxidase (show NOX1 Antibodies) -derived reactive oxygen species generation through activation of p47 phox in a TrkB (show NTRK2 Antibodies) receptor-dependent manner
human p37 (show CCNH Antibodies)/p47 (show ING1 Antibodies) and their C. elegans orthologue UBXN-2 regulate centrosome function in prophase by limiting the recruitment of Aurora A (show AURKA Antibodies)
The binding of p47 (show ING1 Antibodies) to polyubiquitinated NEMO (show IKBKG Antibodies) triggers the lysosomal degradation of NEMO (show IKBKG Antibodies), thereby inhibiting IKK (show CHUK Antibodies) activation.
Data suggest that NADPH oxidase (show NOX1 Antibodies)-derived cytosolic superoxide is increased in islets upon oleate exposure and leads to beta cell dysfunction; whole-body NADPH oxidase (show NOX1 Antibodies) inhibition (via p47 (show MFGE8 Antibodies) knockout) decreases superoxide and restores islet function.
that p47 (show MFGE8 Antibodies) ubiquitin regulatory X domain domains may act as general p97/valosin containing protein (show vcp Antibodies)/CDC48 (show vcp Antibodies) binding modules and that adaptor binding for N-ethylmaleimide sensitive factor (show NSF Antibodies) and p97 (show EIF4G2 Antibodies) might involve different binding sites
genetic ablation of components of NADPH oxidase (show NOX1 Antibodies) enhances susceptibility to the proinflammatory effects of CS leading to airspace enlargement and alveolar damage.
N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
, NSFL1 cofactor p47
, NSFL1 (p97) cofactor (p47)
, p97 cofactor p47
, NSFL1 cofactor p47-like
, SHP1 homolog
, UBX domain-containing protein 2C
, XY body-associated protein XY40