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Natriuretic Peptide Precursor B Proteins (NPPB)

NPPB is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. Additionally we are shipping Natriuretic Peptide Precursor B Antibodies (99) and Natriuretic Peptide Precursor B Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NPPB 4879 P16860
NPPB 25105 P13205
NPPB 396844 P07634
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Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
HOST_Human Human Un-conjugated 500 μg Log in to see 3 to 4 Days

NPPB Proteins by Origin and Source

Origin Expressed in
Rat (Rattus)
Pig (Porcine)

More Proteins for Natriuretic Peptide Precursor B (NPPB) Interaction Partners

Pig (Porcine) Natriuretic Peptide Precursor B (NPPB) interaction partners

  1. CNP and BNP serve as oocyte maturation inhibitor to inhibit oocyte maturation in mammals

  2. ANP and BNP gene expression differs considerably between cardiac chambers in the first 72 hours of life in healthy piglets, resembling the transition from fetal to neonate circulation. The cardiac gene expression does not explain plasma concentrations.

  3. Up-regulation of BNP and a reduction in a ratio of sarcoplasmic reticulum calcium ATPase 2a in failing myocardium are observed in a porcine model of tachycardia.

  4. Data show that all five molecules, BNP, ICAM-1 (show ICAM1 Proteins), TNF-alpha (show TNF Proteins), VCAM-1 (show VCAM1 Proteins) and IL-6 (show IL6 Proteins), quickly and reliably signaled adverse interactions.

  5. identification and characterization of a novel alternatively spliced variant of porcine and human NPPB (show BNP Proteins) resulting from exon 2 skipping

  6. Arial natriuretic factor (ANF (show HESX1 Proteins)) and N-terminal proANF may be better suited than brain natriuretic peptide (show BNP Proteins) as markers of cardiac preload during the development and treatment of acute heart failure.

  7. Regional differences in BNP and CNP (show NPPC Proteins) expression were observed in myocardium with sustained left ventricular dyssynchronous contraction.

Human Natriuretic Peptide Precursor B (NPPB) interaction partners

  1. BNP levels can be used as a clinical indicator to predict short-term prognosis in ST-elevation myocardial infarction patients.

  2. BNP independently predicts perioperative mortality in patients with constrictive pericarditis undergoing pericardiectomy.

  3. The BNP level may be of value in evaluating severity and prognosis in patients with acute lung injury/acute respiratory distress syndrome.

  4. Data show that both furin (show FURIN Proteins) and brain type natriuretic peptide (BNP) were more sensitive than corin (show CORIN Proteins) in predicting cardiovascular complications in type 2 diabetes mellitus (T2DM) patients.

  5. BNP test is a good point-of-care for the management of heart failure despite a relatively poor precision.

  6. B-type natriuretic peptide (show BNP Proteins) levels pre left ventricular assist device implantation may predict ventricular arrhythmia post LVAD implantation.

  7. Data suggest testing for aminoterminal pro-B-type natriuretic peptide (show BNP Proteins) (NT-proBNP) should be performed in the hospitalized very elderly, because of the very high prevalence of underlying heart failure (HF) and its impact on in-hospital mortality.

  8. Data suggest that low serum levels of NT-proBNP are an independent risk factor/biomarker for diagnosis of NAFLD; low serum levels of NT-proBNP correlate with presence of elevated fat accumulation in liver (in a multi-ethnic, cross-sectional study).

  9. Data suggest that risk of diabetes type 2 increases in subjects with asymptomatic atherosclerosis as plasma NT-proBNP levels increase, probably in response to pathophysiological conditions leading to high levels of NT-proBNP (and interleukin 6 (show IL6 Proteins)).

  10. high expression levels of BNP promote the apoptosis of myocardial cells through the lncRNA LSINCT5 mediator.

Natriuretic Peptide Precursor B (NPPB) Protein Profile

Protein Summary

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.

Gene names and symbols associated with NPPB

  • brain natriuretic peptide (BNP)
  • natriuretic peptide B (NPPB)
  • natriuretic peptide B (Nppb)
  • Bnf protein
  • BNP protein
  • BNP1 protein
  • NPPB protein

Protein level used designations for NPPB

gamma-brain natriuretic peptide , natriuretic peptides B , brain type natriuretic peptide , natriuretic peptide precursor B , natriuretic protein , Brain natriuretic factor , brain natriuretic peptide , iso-ANP , natriuretic peptide precursor type B , Gamma-brain natriuretic peptide

396844 Sus scrofa
4879 Homo sapiens
25105 Rattus norvegicus
508734 Bos taurus
493764 Felis catus
100294642 Ovis aries
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