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B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Additionally we are shipping Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 Antibodies (62) and and many more products for this protein.
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B7H6-derived peptides trigger TNF-alpha (show TNF Proteins)-dependent immunostimulatory activity of lymphocytic NK92-MI cells.
Study confirms that B7-H6 is widely expressed in B-cell lymphomas and demonstrates its important role in the pathogenesis and chemosensitivity of lymphoma.
our present data revealed that higher B7-H6 expression in ovarian cancer tissues was positively correlated with tumor metastasis and cancer progression
NKp30 (show NCR3 Proteins)-B7-H6 interaction is a novel cell contact mechanism that mediates activation of Group 2 innate lymphoid cells and identifies a potential target for the development of novel therapeutics for atopic dermatitis and other atopic diseases.
study not only reveals the possibility that tumor therapeutics work as stress inducers to enhance tumor sensitivity to NK cell cytolysis but also suggests that B7-H6 could be a potential target for tumor therapy in the future
Our results suggest that NKP30 (show NCR3 Proteins)-B7-H6 interaction can aggravate hepatocyte damage, probably through up-regulation of IL-32 (show IL32 Proteins) expression in hepatitis B virus-related acute-on-chronic liver failure
the interaction between NKp30 (show NCR3 Proteins) and B7-H6 may contribute to the fate of neuroblastoma (show ARHGEF16 Proteins) patients
Study suggests that B7-H6 has a limited value as a prognostic marker in non-small cell lung cancer patients.
this study identified ectodomain shedding of B7-H6 by the metalloproteases "a disintegrin and metalloproteases" (ADAM)-10 (show ADAM10 Proteins) and ADAM-17 (show ADAM17 Proteins) from the cell surface of tumor cells as a crucial mechanism of expression regulation of B7-H6.
B7-H6-positive carcinomas were significantly associated with a higher differentiation.
B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3\; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009
B7 homolog 6
, natural cytotoxicity triggering receptor 3 ligand 1
, putative Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167