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NCDN encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and may be essential for spatial learning processes. Additionally we are shipping Neurochondrin Kits (10) and Neurochondrin Proteins (7) and many more products for this protein.
Showing 10 out of 60 products:
Human Polyclonal NCDN Primary Antibody for ELISA, ICC - ABIN4338730
Ishiduka, Mochizuki, Yanai, Takatsuka, Nonomura, Niida, Horiguchi, Maeda, Fukamizu: Induction of hydroxyapatite resorptive activity in bone marrow cell populations resistant to bafilomycin A1 by a factor with restricted expression to bone and brain, neurochondrin. in Biochimica et biophysica acta 1999
Show all 5 Pubmed References
Human Polyclonal NCDN Primary Antibody for ELISA, WB - ABIN4338731
Mochizuki, Dateki, Yanai, Ishizuka, Amizuka, Kawashima, Koga, Ozawa, Fukamizu: Targeted disruption of the neurochondrin/norbin gene results in embryonic lethality. in Biochemical and biophysical research communications 2003
Show all 5 Pubmed References
Cow (Bovine) Polyclonal NCDN Primary Antibody for ELISA, WB - ABIN188738
Dateki, Horii, Kasuya, Mochizuki, Nagao, Ishida, Sugiyama, Tanimoto, Yagami, Imai, Fukamizu: Neurochondrin negatively regulates CaMKII phosphorylation, and nervous system-specific gene disruption results in epileptic seizure. in The Journal of biological chemistry 2005
Human Polyclonal NCDN Primary Antibody for IHC, IHC (p) - ABIN4338732
Oku, Takahashi, Fukata, Fukata: In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes. in The Journal of biological chemistry 2013
Schizophrenia subjects compared to controls showed a marked increase in CA1 (show CA1 Antibodies) hippocampal Norbin, and Tamalin (show GRASP Antibodies) proteins (47% and 34% respectively), which are endogenous regulators of mGluR5 (show GRM5 Antibodies) signalling and trafficking
we demonstrate that neurochondrin has strong isoform selectivity towards the RIIa subunit of PKA with nanomolar affinity
In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5 (show RAB5A Antibodies)-positive endosomes.
In mouse, the encoded protein is a negative regulator of Ca/calmodulin-dependent protein kinase II phospho (show CAMK2 Antibodies)rylation and is essential for the spatial learning process.
A novel mechanism of P-Rex1 (show PREX1 Antibodies) regulation through the GPCR (show GPBAR1 Antibodies)-adaptor protein Norbin.
Norbin is a regulator of adult hippocampal neurogenesis and that its deletion causes depressive-like behaviors.
study reports that Norbin, a neuron-specific protein, physically interacts with mGluR5 (show GRM5 Antibodies) in vivo, increases the cell surface localization of the receptor, and positively regulates mGluR5 (show GRM5 Antibodies) signaling
neurochondrin/norbin gene function is essential for the early embryogenesis
Neurochondrin expression pattern in the developing and adult brain.
results showed that neurochondrin is a negative regulator of Ca(2+)/calmodulin-dependent protein kinase II (show CAMK2 Antibodies) phosphorylation and specific homozygous gene disruption resulted in epileptic seizure
This gene encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and may be essential for spatial learning processes. Several alternatively spliced transcript variants of this gene have been described.
, neurochondrin homolog
, M-Sema F-associating protein of 75 kDa
, minisatellite 10ae detected by probe MMS10
, neurite outgrowth-related protein from the rat brain