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NEUROD1 encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. Additionally we are shipping NEUROD1 Proteins (9) and NEUROD1 Kits (4) and many more products for this protein.
Showing 10 out of 101 products:
Human Monoclonal NEUROD1 Primary Antibody for IF, WB - ABIN394313
Jablonski, McAteer, de Bakker, Franks, Pollin, Hanson, Saxena, Fowler, Shuldiner, Knowler, Altshuler, Florez: Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program. in Diabetes 2010
Show all 5 references for ABIN394313
Human Polyclonal NEUROD1 Primary Antibody for EIA, IHC (p) - ABIN357405
Breslin, Zhu, Lan: NeuroD1/E47 regulates the E-box element of a novel zinc finger transcription factor, IA-1, in developing nervous system. in The Journal of biological chemistry 2003
Show all 5 references for ABIN357405
Human Polyclonal NEUROD1 Primary Antibody for WB - ABIN388766
Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002
Show all 3 references for ABIN388766
Human Polyclonal NEUROD1 Primary Antibody for EIA, WB - ABIN357406
Miyachi, Maruyama, Kitamura, Nakamura, Kawakami: Structure and regulation of the human NeuroD (BETA2/BHF1) gene. in Brain research. Molecular brain research 1999
Show all 2 references for ABIN357406
Cow (Bovine) Polyclonal NEUROD1 Primary Antibody for WB - ABIN2779431
Peng, Wang, Meng, Li, Zhang, Li, Chen, Ma, Zhou: ISL1 physically interacts with BETA2 to promote insulin gene transcriptional synergy in non-beta cells. in Biochimica et biophysica acta 2005
during embryonic development, NeuroD governs photoreceptor genesis via non-cell-autonomous mechanisms and that, during photoreceptor development and regeneration, Notch signaling is a mechanistic link between NeuroD and cell cycle exit.
differential levels of Neurod are required to generate endocrine pancreas subtypes from precursors during both embryonic and larval stages
Transcription factor neuroD, involved in retinogenesis, is co-opted by the circadian clock following photoreceptor differentiation.
Nkx2.2 coordinately activates NeuroD1 with Ngn3 in the endocrine progenitor cell and plays a role in the maintenance of NeuroD1 expression to regulate beta cell function in the mature islet.
The control of endocrine cell fate is instead fulfilled by two basic helix-loop-helix factors, Ascl1b and Neurod1 and NEUROG3 (show NEUROG3 Antibodies) is not the unique pancreatic endocrine cell fate determinant in vertebrates.
the quantity, rather than quality (i.e., the ON/OFF states), of neurod expression directly or indirectly determines the two subtypes of posterior lateral line neurons
BrdU-, neuroD (nrd)- and Hu-studies reveal unusual non-ventricular neurogenesis in the postembryonic zebrafish forebrain.
in the zebrafish, two proneural genes are essential for differentiation of the hair cells, neuroD and atonal homolog 1
Coexpressed with cone-rod-homeobox (show CRX Antibodies) transcription factor (Crx (show CRX Antibodies)) in putative cone progenitors and nascent cone photoreceptors. In zebrafish retina, similar genetic cascades may regulate photoreceptor genesis and maturation.
NeuroD plays a fundamental role in photoreceptor genesis by regulating mechanisms that promote rod and cone progenitors to withdraw from the cell cycle.
The authors show that NeuroD1 directly binds regulatory elements of neuronal genes that are developmentally silenced by epigenetic mechanisms.
Expression of Transcription Factor NeuroD1 in Olfactory Bulb Glutamatergic Neurons
Data show that RNA binding protein HuD and special adenine-thymine (AT)-rich DNA-binding protein 1 (SATB1) form a positive regulatory loop that enhances NeuroD1 protein transcription and subsequent neuronal differentiation.
Neurod1 regulates the developments of opioid tolerance via a time-dependent pathway through contextual learning and a short-response pathway through antinociception.
The authors report the generation and characterization of Neurod1-CreER(T2) mouse lines and show that Neurod1 is not only expressed in immature newborn neurons of the adult hippocampus but also in fully mature granule cells of the dentate gyrus.
Study demonstrates a sequential expression order of NEUROD1>ISL1 (show ISL1 Antibodies)>POU4F1 (show POU4F1 Antibodies)>POU4F2 (show POU4F2 Antibodies) during the inner ear neurogenesis.
In this study, we tried to establish an effective method of differentiation through the protein transduction of three transcription factors (Pdx1 (show PDX1 Antibodies), NeuroD, and MafA (show MAFA Antibodies)) important to pancreatic beta cell development.
These data suggest that melatonin, by acting on MT1 receptors, affects NeuroD expression in the gastrointestinal tract and thus might contribute to circadian regulation in metabolic functions.
NeuroD-dependent neuronal death occurs through a Bax (show BAX Antibodies)-dependent apoptotic pathway
This study demonistrated that NeuroD modulates opioid agonist-selective regulation of adult neurogenesis and contextual memory extinctionin mice.
Premature misexpression of NeuroD1 in chick partially recapitulates the amphibian condition by suppressing transit amplification.
NeuroD1 gene activity is turned on in new born neurons during post-metamorphic neurogenesis.
NeuroD promoter is substantially more sensitive to the phosphorylation status of Ngn2 (show NEUROG2 Antibodies) than the Delta promoter, and that this can be attributed to differences in the ease of promoter activation.
This study reveals that the early larval stage in Xenopus (Stage 48) displays patterns of proliferation (NeuroD).
Data demonstrate that Neurogenin and NeuroD preferentially recognize neurogenesis-related targets through an enhancer signature of clustered consensus-binding sites and regulate neurogenesis by activating a core set of transcription factors.
RNAi of lentiviral vector target NeuroD can reduce the migration and invasion abilities of PANC-1 cells
this study concludes that the novel mechanism would regulate the expression of ALK (show ALK Antibodies) in neuroblastoma (show ARHGEF16 Antibodies) and that NeuroD1 should be significantly involved in neuroblastoma (show ARHGEF16 Antibodies) tumorigenesis.
NEUROD1 is important for maintenance of the retina function and partial loss-of-function mutation in NEUROD1 is likely a rare cause of nonsyndromic ARRP.
Increased expression of NeuroD1 subsequently leads to regulation of expression and function of the nicotinic acetylcholine receptor subunit cluster of alpha3, alpha5, and beta4.
Transactivation of Ctbp (show CTBP2 Antibodies) was dependent on the histone H3 (show HIST3H3 Antibodies) lysine 9 (H3K9) demethylase (show MBD2 Antibodies) activity of LSD1 (show KDM1A Antibodies) facilitates subsequent H3K9 acetylation by the NeuroD1-associated histone acetyltransferase (show HAT Antibodies), P300/CBP-associated factor (show KAT2B Antibodies).
Gene expression profiling revealed that permissive lines are typified by lower expression of the early neurogenic transcription factor ASCL1 and, conversely, by higher expression of the late neurogenic transcription factor NEUROD1.
NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB (show NTRK2 Antibodies) and NCAM (show NCAM1 Antibodies).
The overexpression of NeuroD may contribute to the tumorogenesis and development of pancreatic carcinoma, and is closely correlated to the cancer cell proliferation, p53 (show TP53 Antibodies) signal pathway and neural invasion.
Combined transfection of the three transcriptional factors, PDX-1 (show PDX1 Antibodies), NeuroD1, and MafA (show KLRG1 Antibodies), causes differentiation of bone marrow mesenchymal stem cells into insulin (show INS Antibodies)-producing cells
Photosensitive photoreceptor cells can be generated by combinations of transcription factors. The combination of CRX and RX generate immature photoreceptors: and additional NEUROD promotes maturation.
Report pancreatic expression of NeuroD1 in pancreas.
NeuroD might be an essential regulatory factor for transcription of pig AgRP (show AGRP Antibodies), playing a role in energy homeostasis regulation in the porcine and human brain.
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
, neurogenic differentiation factor 1
, beta-cell E-box transcriptional activator 2
, neurogenic differentiation 1
, basic helix-loop-helix transcription factor
, beta-cell E-box transactivator 2
, class A basic helix-loop-helix protein 3
, neurogenic helix-loop-helix protein NEUROD
, basic helix-loop-helix factor 1
, Beta-cell E-box transcriptional activator 2
, Neurogenic differentiation factor 1