NEUROD1 antibody (AA 26-91)

Catalog No. ABIN1724757

Cited in 2+ publications. The Mouse Monoclonal anti-NEUROD1 antibody (Clone 6E9G12) (ABIN1724757) specifically detects NEUROD1 in ELISA. The antibody is reactive with Human, Mouse and Monkey samples.

Quick Overview for NEUROD1 antibody (AA 26-91) (ABIN1724757)

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Reactivity: Human, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This NEUROD1 antibody is un-conjugated

Application: ELISA

Clone: 6E9G12

Product Details anti-NEUROD1 Antibody

Binding Specificity: AA 26-91

Purpose: Neurod Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human Neurod (AA: 26-91 ) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-NEUROD1 antibody (ABIN1724757)

Huang, Kishida, Cao, Murakami-Tonami, Mu, Nakaguro, Koide, Takeuchi, Onishi, Kadomatsu: "The neuronal differentiation factor NeuroD1 downregulates the neuronal repellent factor Slit2 expression and promotes cell motility and tumor formation of neuroblastoma." in: Cancer research, Vol. 71, Issue 8, pp. 2938-48, (2011) (PubMed).

Shimoda, Chen, Noguchi, Matsumoto, Grayburn: "Neurogenic differentiation 1 directs differentiation of cytokeratin 19-positive human pancreatic nonendocrine cells into insulin-producing cells." in: Transplantation proceedings, Vol. 42, Issue 6, pp. 2071-4, (2010) (PubMed).

Target Details for NEUROD1

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Alternative Name: Neurod

Background: This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.

Molecular Weight: 40 kDa

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis