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Neutrophil Cytosolic Factor 4 Proteins (NCF4)

Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. Additionally we are shipping Neutrophil Cytosolic Factor 4 Antibodies (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NCF4 17972 P97369
Rat NCF4 NCF4 500904  
NCF4    
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Top Neutrophil Cytosolic Factor 4 Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$788.70
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$838.20
Details

NCF4 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human

More Proteins for Neutrophil Cytosolic Factor 4 (NCF4) Interaction Partners

Mouse (Murine) Neutrophil Cytosolic Factor 4 (NCF4) interaction partners

  1. p40phox deficiency leads to upregulation of chemokine receptor 1 (show CMKLR1 Proteins) and downregulation of fucosyltransferases and sialyltransferases involved in glycan modifications during experimental intestinal inflammation.

  2. cooperation of p40(phox) with p47(phox) for Nox2 (show CYBB Proteins)-based NADPH oxidase (show NOX1 Proteins) activation during Fcgamma receptor (FcgammaR)-mediated phagocytosis

  3. The defect in Reactive Oxygen Species production and killing of s aureus by p40(phox-/-) neutrophils defines p40(phox) as an essential component in bacterial killing.

  4. p40 (show LANCL1 Proteins)(phoxR58A/R58A) embryos do not develop normally but p40 (show LANCL1 Proteins)(phoxR58A/-) mice are viable and neutrophils from these animals exhibit significantly reduced oxidase responses compared to those from their p40(phox+/-) siblings.

  5. Class III PI3K Vps34 (show PIK3C3 Proteins) is responsible for the synthesis of PtdIns(3)P on phagosomes containing either S aureus or E coli. PtdIns(3)P binding to p40(phox) is important for CD18 (show ITGB2 Proteins)-dependent activation oxidase activation in response to S aureus and E coli

  6. p40(phox) is prephosphorylated in resting endothelial cells and can compensate p47(phox) in keeping basal ROS (show ROS1 Proteins) production.

Neutrophil Cytosolic Factor 4 (NCF4) Protein Profile

Protein Summary

Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. It may be important for the assembly and/or activation of the NADPH-oxidase complex.

Gene names and symbols associated with NCF4

  • neutrophil cytosolic factor 4 (Ncf4)
  • AI451400 protein
  • p40phox protein

Protein level used designations for NCF4

NCF-4 , neutrophil NADPH oxidase factor 4 , neutrophil cytosol factor 4 , p40-phox

GENE ID SPECIES
17972 Mus musculus
500904 Rattus norvegicus
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