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anti-Nicotinamide Nucleotide Transhydrogenase (NNT) Antibodies

NNT encodes an integral protein of the inner mitochondrial membrane. Additionally we are shipping NNT Proteins (7) and NNT Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NNT 23530 Q13423
NNT 18115  
NNT 310378  
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Top anti-NNT Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-NNT Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human Liver Host: Rabbit  Target Name: NNT  Sample Tissue: Hela Whole cell  Lane A:  Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1 µg/mL Peptide Concentration: 5 µg/mL Lysate Quantity: 41 µg/lane/LaneGel Concentration:.12 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, ELISA, WB NNT monoclonal antibody (M01), clone 1D6 Western Blot analysis of NNT expression in HepG2 . Immunofluorescence of monoclonal antibody to NNT on HepG2 cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Cow Rabbit Un-conjugated WB Western blot analysis of NNT expression in HEK293T (A), NIH3T3 (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image NNT antibody detects NNT protein by Western blot analysis. A. 30 µg 293T whole cell lysate/extract B. 30 µg HeLa whole cell lysate/extract C. 30 µg HepG2 whole cell lysate/extract | D. 30 µg A375 whole cell lysate/extract 7.5 % SDS-PAGE NNT antibody , dilution: 1:1000 IHC-P Image NNT antibody detects NNT protein at cytosol on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. NNT antibody , dilution: 1:500. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded dog thyroid labeled with Rabbit Anti-NNT Polyclonal Antibody, Unconjugated (ABIN709631) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human kidney labeled with Rabbit Anti-NNT Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to NNT on HepG2 cell (antibody concentration 10 µg/mL). NNT monoclonal antibody (M01), clone 1D6 Western Blot analysis of NNT expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB NNT antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

NNT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine) ,


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Rat (Rattus) ,


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Top referenced anti-NNT Antibodies

  1. Chicken Polyclonal NNT Primary Antibody for WB - ABIN2782785 : Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: The LIFEdb database in 2006. in Nucleic acids research 2005 (PubMed)

  2. Human Monoclonal NNT Primary Antibody for IF, ELISA - ABIN565110 : Picklo: Ethanol intoxication increases hepatic N-lysyl protein acetylation. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against NNT Interaction Partners

Caenorhabditis elegans (C. elegans) Nicotinamide Nucleotide Transhydrogenase (NNT) interaction partners

  1. nnt-1 is important in the defense against mitochondrial oxidative stress

Human Nicotinamide Nucleotide Transhydrogenase (NNT) interaction partners

  1. This report of a novel NNT mutation, p.G200S, expands the phenotype of NNT mutations to include mineralocorticoid deficiency. It provides the first evidence that NNT mutations can cause oxidative stress and mitochondrial defects.

  2. Data suggest mutations in nicotinamide nucleotide transhydrogenase (NNT) as contributory to left ventricular noncompaction (LVNC).

  3. NNT mRNA expression is significantly higher in visceral fat of obese patients and correlates with body weight, BMI, % body fat, visceral and sc fat area, waist and hip circumference, and fasting plasma insulin (show INS Antibodies).

  4. Results suggest that NNT may have a role in ROS (show ROS1 Antibodies) detoxification in human adrenal glands.

  5. In the failing heart a partial loss of Nnt activity adversely impacts NADPH (show NQO1 Antibodies)-dependent enzymes and the capacity to maintain membrane potential, thus contributing to a decline in bioenergetic capacity, redox regulation and antioxidant defense.

Mouse (Murine) Nicotinamide Nucleotide Transhydrogenase (NNT) interaction partners

  1. Pathologic workload reverses Nnt to deplete NADPH (show FDXR Antibodies) and antioxidative capacity. Reverse Nnt induces mitochondrial oxidative stress and necrosis.

  2. In mitochondria, genetic or pharmacological disruptions in the PDHC-NNT redox circuit negate counterbalance changes in energy expenditure

  3. Data conclude that Herpud1 (show HERPUD1 Antibodies) regulates insulin (show INS Antibodies) secretion via control of Nnt expression.

  4. our data suggest that NNT functions as a high-capacity source of mitochondrial NADPH (show FDXR Antibodies) and that its functional loss due to the Nnt mutation results in mitochondrial redox abnormalities

  5. the role of NNT in regulating central carbon metabolism via redox balance, calling for other mechanisms that coordinate substrate preference to maintain a functional TCA cycle.

  6. Our results demonstrate a novel role for NNT as a regulator of macrophage-mediated inflammatory responses

  7. A normal Nnt allele can help with better cardiac function in MnSOD (show SOD2 Antibodies)-deficient mice during fetal development.

  8. The presence of a truncated Nnt did not affect insulin (show INS Antibodies) secretion or glucose tolerance on the C57BL/6 background.

  9. Nnt was identified as a novel candidate gene for contribution to glucose intolerance through reduced beta cell activity.

  10. Mutations/deletion uncouple pancreatic beta cell mitochondrial metabolism leading to less ATP production, enhanced KATP channel activity, and consequently impaired insulin (show INS Antibodies) secretion.

NNT Antigen Profile

Protein Summary

This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.

Gene names and symbols associated with NNT

  • Nicotinamide Nucleotide Transhydrogenase (nnt-1) antibody
  • nicotinamide nucleotide transhydrogenase (AFUA_5G02780) antibody
  • nicotinamide nucleotide transhydrogenase (nnt) antibody
  • nicotinamide nucleotide transhydrogenase (NNT) antibody
  • nicotinamide nucleotide transhydrogenase (Nnt) antibody
  • 4930423F13Rik antibody
  • Afu5g02780 antibody
  • AI323702 antibody
  • BB168308 antibody
  • GCCD4 antibody
  • wu:fa20d10 antibody
  • wu:fc86a04 antibody
  • zgc:76979 antibody

Protein level used designations for NNT

Nicotinamide Nucleotide Transhydrogenase family member (nnt-1) , nicotinamide nucleotide transhydrogenase , NAD(P) transhydrogenase, mitochondrial , pyridine nucleotide transhydrogenase , Nicotinamide nucleotide transhydrogenase (NAD(P)+ transhydrogenase)

GENE ID SPECIES
180884 Caenorhabditis elegans
3505502 Aspergillus fumigatus Af293
100158572 Xenopus (Silurana) tropicalis
23530 Homo sapiens
18115 Mus musculus
310378 Rattus norvegicus
406619 Danio rerio
447528 Xenopus laevis
427196 Gallus gallus
280878 Bos taurus
479342 Canis lupus familiaris
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