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NNT antibody (N-Term)

NNT Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782785
  • Target See all NNT Antibodies
    NNT (Nicotinamide Nucleotide Transhydrogenase (NNT))
    Binding Specificity
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 35
    • 27
    • 15
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Horse
    Host
    • 32
    • 3
    Rabbit
    Clonality
    • 33
    • 2
    Polyclonal
    Conjugate
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NNT antibody is un-conjugated
    Application
    • 28
    • 13
    • 13
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    IVRGFDTRAA ALEQFKSLGA EPLEVDLKES GEGQGGYAKE MSKEFIEAEM
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against NNT. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human NNT
    Top Product
    Discover our top product NNT Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1086 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

  • Target
    NNT (Nicotinamide Nucleotide Transhydrogenase (NNT))
    Alternative Name
    NNT (NNT Products)
    Synonyms
    Afu5g02780 antibody, GCCD4 antibody, 4930423F13Rik antibody, AI323702 antibody, BB168308 antibody, wu:fa20d10 antibody, wu:fc86a04 antibody, zgc:76979 antibody, Nicotinamide Nucleotide Transhydrogenase antibody, nicotinamide nucleotide transhydrogenase antibody, nicotinamide nucleotide transhydrogenase L homeolog antibody, nnt-1 antibody, AFUA_5G02780 antibody, nnt antibody, NNT antibody, Nnt antibody, nnt.L antibody
    Background
    NNT is an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.
    Alias Symbols: MGC126502, MGC126503
    Protein Interaction Partner: MVP, UBC, TIMM10, PTCD1, FKBP8, POFUT1, UQCR11, ATP6V1F, PRPF3, LAMTOR3, SF1, THY1, ABCD3, NDUFS6, NDUFA9, SLC26A2, ATP5B, SLC25A6, SIRT7, MME, HNRNPA1,
    Protein Size: 1086
    Molecular Weight
    114 kDa
    Gene ID
    23530
    NCBI Accession
    NM_012343, NP_036475
    UniProt
    Q13423
    Pathways
    Proton Transport
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