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anti-Nipped-B Homolog (Drosophila) (NIPBL) Antibodies

NIPBL encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. Additionally we are shipping NIPBL Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NIPBL 25836 Q6KC79
NIPBL 71175 Q6KCD5
NIPBL 294787  
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Top anti-NIPBL Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated ELISA, WB Western blot using antibodies-online's 1 2 Affinity Purified anti-IDN3 antibody shows detection of bands at ~315 kDa and ~125 kDa corresponding to isoforms of IDN3 (arrowheads) in mouse heart whole cell tissue extract. Approximately 35 ug of lysate was separated on a 4-8% gel by SDS-PAGE and transferred onto nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 1:1,500. Reaction occurred overnight at 4 100 μg Log in to see 2 to 3 Days
$369.00
Details
Human Rat Un-conjugated IF, IHC (p), IP, WB Anti-NIPBL antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1103259 concentration 10 ug/ml. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Dog Goat Un-conjugated EIA, IHC (fro), IHC (p)   0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rat Un-conjugated IF, IHC (p), IP, WB   0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Rat Un-conjugated IF, IHC (p), IP, WB   0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Mouse Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Mouse Rat Un-conjugated ICC, IP, WB   100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IP   100 μL Log in to see 8 to 10 Days
$815.83
Details

NIPBL Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-NIPBL Antibodies

  1. Cow (Bovine) Polyclonal NIPBL Primary Antibody for EIA, WB - ABIN401167 : Gillis, McCallum, Kaur, DeScipio, Yaeger, Mariani, Kline, Li, Devoto, Jackson, Krantz: NIPBL mutational analysis in 120 individuals with Cornelia de Lange syndrome and evaluation of genotype-phenotype correlations. in American journal of human genetics 2004 (PubMed)
    Show all 3 references for ABIN401167

More Antibodies against NIPBL Interaction Partners

Zebrafish Nipped-B Homolog (Drosophila) (NIPBL) interaction partners

  1. Nipbl and mediator cooperatively regulate gene expression to control limb development.

  2. The present s (show WNT2 Antibodies)tudy focuses on th (show CCND1 Antibodies)e role of the zebrafish nipblb paralog during neural development.

  3. Nipbl-deficient embryos showed changes in the expression of genes involved in the specification of endoderm, which gives rise to gut (show GUSB Antibodies) and provides a substrate for cardiac precursor migration, as well as genes that regulate left-right asymmetry

Human Nipped-B Homolog (Drosophila) (NIPBL) interaction partners

  1. NIPBL gene mutation is associated with Thrombocytopenia in Cornelia de Lange syndrome.

  2. This study provides insight into the molecular pathology of Cornelia de Lange syndrome by establishing a relationship between NIPBL and HDAC8 (show HDAC8 Antibodies) mutations and PKR (show PKLR Antibodies) activation.

  3. NIPBL expression conferred poor prognosis and resistance to chemotherapy in non-small cell lung cancer

  4. Scc2 normally promotes a gene expression program that supports translational fidelity. . translational dysfunction may contribute to the human disorder Cornelia de Lange syndrome, which is caused by mutations in NIPBL, the human ortholog of SCC2.

  5. There was an increased frequncy of NIPBL mutations in a cohort of prenatal ultrasound detected phenotypes of Cornelia de Lange syndrome.

  6. A new Sanger sequencing reveals new hidden mutations in NIPBL gene not detected with conventional approach.

  7. analysis of the mutation spectrum of NIPBL in in Chinese patients with Cornelia de Lange syndrome

  8. Nine mutations affecting splice-sites in the NIPBL gene and four new splicing isoforms DeltaE10, DeltaE12, DeltaE33,34, and B' was identified in twelve CdLS patients.

  9. defects of NIPBL might lead to cohesin-loading defects and thereby alter gene expression and second, NIPBL deficiency might affect genes directly via its role at the respective promoters.

  10. Results show that NIPBL has a function in modulating chromatin architecture that is not dependent on SMC3 (show SMC3 Antibodies)/cohesin or CTCF (show CTCF Antibodies) in classical Cornelia de Lange syndrome.

Mouse (Murine) Nipped-B Homolog (Drosophila) (NIPBL) interaction partners

  1. This study provides insight into the molecular pathology of Cornelia de Lange syndrome by establishing a relationship between NIPBL and HDAC8 (show HDAC8 Antibodies) mutations and PKR (show EIF2AK2 Antibodies) activation.

  2. expression analysis of Smc1a (show SMC1A Antibodies) and Nipbl in developing mouse embryos reveals a specific pattern in the hindbrain

  3. Nipbl and mediator cooperatively regulate gene expression to control limb development.

  4. Nipbl+/- mutants are growth-retarded and exhibit various skeletal and craniofacial malformations.

  5. In spermatocytes, Nipbl/Mau2 (show KIAA0892 Antibodies) then relocalises to chromocenters, whereas in oocytes it remains bound to chromosomal axes throughout prophase to dictyate arrest.

  6. Reduction of Nipbl is associated with Cornelia de Lange Syndrome.

  7. Mice heterozygous for a gene-trap mutation in Nipbl were produced and exhibited defects characteristic of Cornelia de Lange Syndrome.

NIPBL Antigen Profile

Protein Summary

This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NIPBL

  • Nipped-B homolog (NIPBL) antibody
  • Nipped-B homolog (nipbl-b) antibody
  • nipped-B homolog (NIPBL) antibody
  • Nipped-B homolog (Drosophila) (NIPBL) antibody
  • nipped-b homolog b (Drosophila) (nipblb) antibody
  • Nipped-B homolog (Drosophila) (nipbl) antibody
  • Nipped-B homolog (Drosophila) (Nipbl) antibody
  • 4921518A06Rik antibody
  • 4933421G18Rik antibody
  • C79399 antibody
  • CDLS antibody
  • CDLS1 antibody
  • Idn3 antibody
  • IDN3-B antibody
  • NIPBL antibody
  • nipbla antibody
  • Scc2 antibody
  • scc2-2 antibody
  • SCC2W antibody
  • wu:fi33d08 antibody

Protein level used designations for NIPBL

Nipped-B homolog , Scc2-2A , Scc2-2B , delangin , sister chromatid cohesion establishment factor 2 , nipped-B homolog , Nipped-B homolog (Drosophila) , nipped-B like a , nipped-B-like protein B , nipped-B-like protein-like , SCC2 homolog , nipped-B-like protein , sister chromatid cohesion 2 homolog , delangin homolog

GENE ID SPECIES
427025 Gallus gallus
450215 Xenopus laevis
771363 Gallus gallus
427439 Gallus gallus
461917 Pan troglodytes
701209 Macaca mulatta
794108 Danio rerio
100014459 Monodelphis domestica
100053547 Equus caballus
100077677 Ornithorhynchus anatinus
100164947 Acyrthosiphon pisum
100403994 Callithrix jacchus
100479499 Ailuropoda melanoleuca
100561843 Anolis carolinensis
100603589 Nomascus leucogenys
100624231 Sus scrofa
25836 Homo sapiens
100172233 Pongo abelii
489226 Canis lupus familiaris
539566 Bos taurus
71175 Mus musculus
294787 Rattus norvegicus
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