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anti-Nodal Homolog (Mouse) (NODAL) Antibodies

The protein encoded by NODAL is a member of the TGF-beta superfamily. Additionally we are shipping Nodal Kits (4) and Nodal Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NODAL 294503  
NODAL 18119 P43021
NODAL 4838 Q96S42
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Top anti-Nodal Antibodies at antibodies-online.com

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Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, WB 50 μL Log in to see 5 to 6 Days
$590.80
Details

NODAL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus) , ,

Mouse (Murine) , ,

Human , ,

More Antibodies against Nodal Interaction Partners

Cow (Bovine) Nodal Homolog (Mouse) (NODAL) interaction partners

Mouse (Murine) Nodal Homolog (Mouse) (NODAL) interaction partners

  1. The finding that Foxh1 (show FOXH1 Antibodies)-Grg (show AES Antibodies)-mediated repression is not essential for Nodal expression during mouse embryogenesis suggests that other regulators compensate for the loss of repressive regulatory input that is mediated by Grg (show AES Antibodies) interactions.

  2. The Nodal morphogen (show SHH Antibodies) gradient induces distinct gene expression patterns during zebrafish embryogenesis.

  3. HEB (show FREM1 Antibodies) is a fundamental link between Nodal signalling, the derepression of a specific class of poised promoters during differentiation, and lineage specification in mouse embryonic stem cells

  4. Studies indicate that the pair of Nodal and Lefty (Lefty1 and Lefty2 (show LEFTY2 Antibodies)) has a conserved role in left-right asymmetry.

  5. Studies indicate that Nodal/Smad2 (show SMAD2 Antibodies)-dependent signals govern initial proximal-distal polarity and formation of the anterior visceral endoderm (AVE).

  6. Meteorin (show METRN Antibodies) is a novel regulator of Nodal transcription

  7. This implies that Gdf1 (show GDF1 Antibodies) potentiates Nodal activity by stabilizing a low molecular weight fraction that is susceptible to neutralization by soluble Acvr2 (show ACVR2A Antibodies).

  8. The consequent prolonged Nodal activity in the node by the absence of Cerl2 (show DAND5 Antibodies) affects local Nodal expression and prolongs its expression in the lateral plate mesoderm.

  9. The combined inhibition of Nodal and BMP signaling resulted in the accumulation of Nanog-negative cells, even in the presence of LIF, uncovering a shared role for BMP and Nodal signaling in maintaining Nanog expression and repression of differentiation.

  10. Snail (show SNAI1 Antibodies) knockdown abolished the Nodal-induced epithelial-mesenchymal transition in B16 cells

Human Nodal Homolog (Mouse) (NODAL) interaction partners

  1. The MSX2 controls mesendoderm lineage commitment by simultaneous suppression of SOX2 (show SOX2 Antibodies) and induction of NODAL expression through direct binding and activation of the Nodal promoter.

  2. During a maturation phase, a fast acting NODAL loop stimulates its own activity and temporarily inhibits BMP signaling. During the stabilization phase, a slow acting NODAL loop, involving WNTs re-establishes BMP signaling and the pluripotency circuitry.

  3. Nodal signaling pathway has subtle changes in the endometrium of women with endometriosis, but this imbalance may not cause functional damage as it seems not to affect the nuclear expression of SMAD4 (show SMAD4 Antibodies).

  4. The expression of lefty (show LEFTY2 Antibodies) in RCC (show XRCC1 Antibodies) cells was lower than that in adjacent non-tumor cells, which may result in the overexpression of nodal, thereby promoting the growth of RCC (show XRCC1 Antibodies).

  5. Nodal induces signal transduction through the Smad2 (show SMAD2 Antibodies)/3-dependent pathway in vitro. Results that Nodal promotes pancreatic cancer cell migration and invasion and induces epithelial-mesenchymal transition.

  6. we found that Kl treatment impairs Nodal mRNA expression and Fgf9-mediated Nanos2 (show NANOS2 Antibodies) induction, reinforcing the antagonistic effect of these two growth factors on the meiotic fate of male germ cells

  7. our studies provide mechanistic insights into Nodal signaling and Nodal inhibition with Cerberus (show CER1 Antibodies) and highlight the potential value of Cerberus (show CER1 Antibodies) as anti-Nodal therapeutic.

  8. Lefty (show LEFTY2 Antibodies) reduced the levels of phosphorylated Smad2 (show SMAD2 Antibodies), Smad3 (show SMAD3 Antibodies), and ERK1/2 (show MAPK1/3 Antibodies), inhibited the proliferation and invasion of glioma cells, and increased their apoptosis.

  9. The data suggest that ERK (show EPHB2 Antibodies) activation by Nodal signaling regulates c-myc (show MYC Antibodies) and p27 (show PAK2 Antibodies) proteins post-translationally and that this cascade is essential for aggressive breast tumor behavior in vivo.

  10. Inhibition of activin (show Actbeta Antibodies)/nodal signaling leads to formation of extravillous trophoblast, whereas loss of activin (show Actbeta Antibodies)/nodal inhibition leads to the formation of syncytiotrophoblasts

Xenopus laevis Nodal Homolog (Mouse) (NODAL) interaction partners

  1. Data show taht combined Wnt (show WNT2 Antibodies) and Nodal signaling synergistically activates transcription of Spemann organizer genes.

  2. Data suggest that Coco (show DAND5 Antibodies) acts as a critical target of flow, suggesting that symmetry is broken by flow-mediated left-asymmetric release of Nodal repression at the midline.

  3. Data show that rapid differential transport of Nodal and Lefty (show LEFTY2 Antibodies) on sulfated (show SULF1 Antibodies) proteoglycan (show Vcan Antibodies)-rich extracellular matrix regulates left-right asymmetry in Xenopus.

  4. Unilateral expression of Xnr-1 in the left lateral plate mesoderm directs the orientation of the left-right axis by driving the left-specific gene cascade.

  5. asymmetric expression of Nodal-related 1 (Xnr1) begins in the posterior left lateral plate mesoderm shortly after the initiation of bilateral perinotochordal expression in the posterior tailbud

  6. Xnr1 and derriere (show GDF3 Antibodies) are coexpressed in the posterior paraxial mesoderm at neurula stage, and with Coco (show DAND5 Antibodies) define a posttranscriptionally regulated signaling center in the chain leading to an increased TGF-beta (show TGFB1 Antibodies) signal on the left side of the embryo.

Nodal (NODAL) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the TGF-beta superfamily. Studies of the mouse counterpart suggested that this gene may be essential for mesoderm formation and subsequent organization of axial structures in early embryonic development.

Gene names and symbols associated with NODAL

  • nodal growth differentiation factor (Nodal) antibody
  • nodal homolog (mouse) (NODAL) antibody
  • nodal (Nodal) antibody
  • nodal growth differentiation factor (NODAL) antibody
  • nodal growth differentiation factor (nodal) antibody
  • nodal homolog 1 (nodal1) antibody
  • HTX5 antibody
  • nodal antibody
  • nodal4 antibody
  • nodal4-A antibody
  • nr1 antibody
  • nr1-A antibody
  • nr4 antibody
  • Tg.413d antibody
  • Xnr-1 antibody
  • xnr4 antibody

Protein level used designations for NODAL

nodal-related protein 1 , nodal homolog (mouse) , nodal homolog , Nodal protein , nodal homolog-like , early embryo mesoderm formation , transgenic lethal 413.d , Nodal homolog 4 , Xnr-4 , nodal homolog 4-A , nodal-related protein 4-A , nodal-related 1, induction of axial mesoderm , nr-1 , xnr1

GENE ID SPECIES
294503 Rattus norvegicus
395205 Gallus gallus
466100 Pan troglodytes
489028 Canis lupus familiaris
530748 Bos taurus
710424 Macaca mulatta
780406 Sus scrofa
100406643 Callithrix jacchus
100453474 Pongo abelii
100588745 Nomascus leucogenys
18119 Mus musculus
4838 Homo sapiens
398068 Xenopus laevis
378543 Xenopus laevis
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