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NONO encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. Additionally we are shipping NONO Proteins (8) and NONO Kits (4) and many more products for this protein.
Showing 10 out of 115 products:
Human Polyclonal NONO Primary Antibody for IHC (p), WB - ABIN657703
Marko, Leichter, Patrinou-Georgoula, Guialis: hnRNP M interacts with PSF and p54(nrb) and co-localizes within defined nuclear structures. in Experimental cell research 2010
Show all 4 references for ABIN657703
Dog (Canine) Monoclonal NONO Primary Antibody for BI, WB - ABIN968450
Basu, Dong, Krainer, Howe: The intracisternal A-particle proximal enhancer-binding protein activates transcription and is identical to the RNA- and DNA-binding protein p54nrb/NonO. in Molecular and cellular biology 1997
Show all 3 references for ABIN968450
Chicken Polyclonal NONO Primary Antibody for IF, WB - ABIN2779027
Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006
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Human Polyclonal NONO Primary Antibody for IHC, IHC (p) - ABIN151100
Zhang, Zhang, Shen, Burks, Zhang, Wang, LeMaire, Yoshimura, Aoki, Coselli, Wang: TNF-alpha suppresses prolyl-4-hydroxylase alpha1 expression via the ASK1-JNK-NonO pathway. in Arteriosclerosis, thrombosis, and vascular biology 2007
Show all 3 references for ABIN151100
Cow (Bovine) Polyclonal NONO Primary Antibody for IF, IHC - ABIN2779028
Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ... in Genome research 2006
Show all 2 references for ABIN2779028
Human Polyclonal NONO Primary Antibody for IHC (p), IHC - ABIN251463
Brown, Ripperger, Kadener, Fleury-Olela, Vilbois, Rosbash, Schibler: PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator. in Science (New York, N.Y.) 2005
p54(nrb) is a novel regulator of SREBP-1a in the nucleus, and the data suggest that p54(nrb) regulation of SREBP-1a supports the increased cellular demand of lipids for breast cancer growth.
Data uncover a new role for NONO in mediating the cellular response to UV-induced DNA damage.
p54nrb and hnRNPM knockdown silences the FGF1 promoter-dependent accumulation of mRNA during myoblast differentiation.
Subnuclear re-localization of SOX10 (show SOX10 Antibodies) and p54NRB correlates with a unique neurological phenotype associated with SOX10 (show SOX10 Antibodies) missense mutations
These data suggest that NonO negatively regulates HIV-1 infection in CD4 (show CD4 Antibodies)(+) T cells, highlighting the importance of host proteins associated with HIV-1 preintegration complexes in regulating viral replication.
Mutations in NONO led to defects at inhibitory synapses in intellectual disability syndrome.
Patients with aortic dissection (AD)exhibited significantly decreased expression of P54(nrb) /NonO. The significant correlation between P54(nrb) /NonO and collagen may point to novel thinking about collagen metabolism research in AD aorta.
silencing p54(nrb)/NONO expression in H295R human adrenocortical cells decreases the ability of the cells to increase intracellular cAMP production and subsequent cortisol biosynthesis in response to adrenocorticotropin hormone (ACTH (show POMC Antibodies)) stimulation.
The ability of the SFPQ (show SFPQ Antibodies)/NONO complex to form varying protein assemblies, in conjunction with the effect of post-translational modifications of SFPQ (show SFPQ Antibodies) modulating mRNA binding, suggests key roles affecting mRNP dynamics within the cell.
p54 (show DDX6 Antibodies) is essential for GC-mediated expression of occludin (show OCLN Antibodies), claudin-5 (show CLDN5 Antibodies), and barrier induction, and the p54 (show DDX6 Antibodies)/PSF (show IGFBP7 Antibodies) heterodimer may contribute to normal blood-retinal barrier (BRB (show PTBP1 Antibodies)) induction in vivo.
mechanisms have therapeutic implications for reducing beta-cell proliferation in insulinomas by inhibiting phospho-HLXB9 or its interaction with Nono and modulating the expression of its direct (Cblb) or indirect (c-Met) targets
Cytoplasmic granule containing HERMES (show CD44 Antibodies), NonO, PSF (show Il3 Antibodies), and G3BP1 (show G3BP1 Antibodies) is a neuronal RNA-protein granule that is transported in neurites during retinal differentiation.
Quantitative proteomics reveals dynamic interaction of JNK (show MAPK8 Antibodies) with RNA transport granule proteins Sfpq (show SFPQ Antibodies) and Nono during neuronal differentiation
We analyzed the expression of sperm-specific Akap3 (show AKAP3 Antibodies) and the potential regulatory factors of its protein synthesis during mouse spermiogenesis.
NONO genetic insufficiency led to upregulation of PSPC1 (show PSPC1 Antibodies), which replaced NONO in a stable complex with SFPQ (show SFPQ Antibodies).
Dsta indicate that NONO bound to p16-Ink4A (show CDKN2A Antibodies) cell cycle checkpoint gene and potentiated its circadian activation in a PER protein-dependent fashion.
Basal and cyclic AMP (show TMPRSS5 Antibodies)-induced Rbp4 (show RBP4 Antibodies) transcription is regulated by a multiprotein complex that is similar to ones that modulate expression of genes of steroid hormone biosynthesis.
p54nrb is a target of the peptidylprolyl isomerase Pin1 (show PIN1 Antibodies), suggesting that it may be regulated by phosphorylation-dependent conformational changes as many other nuclear proteins upon entry into mitosis
identified two proteins, NONO and WDR5 (show WDR5 Antibodies), that can associate with the mammalian PER1 (show PER1 Antibodies) protein; data suggest that NONO probably operates antagonistically to PER proteins in mammalian cells, and that it is essential to normal circadian rhythmicity
PSPC1 (show PSPC1 Antibodies), NONO, and SFPQ (show SFPQ Antibodies) form complexes with each other in Sertoli cells and may regulate androgen receptor (show AR Antibodies)-mediated transcriptional activity
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.
54 kDa nuclear RNA- and DNA-binding protein
, 55 kDa nuclear protein
, DNA-binding p52/p100 complex, 52 kDa subunit
, non-POU domain-containing octamer (ATGCAAAT) binding protein
, non-POU domain-containing octamer-binding protein
, non-POU-domain-containing, octamer-binding protein
, 54 kD nuclear RNA-binding protein